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Cited by 199

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

RAD51 -Dependent Break-Induced Replication in Yeast

Open access
Davis, Allison P., Symington, Lorraine S.·2004·Molecular and Cellular Biology

Abstract

A chromosome fragmentation assay was used to measure the efficiency and genetic control of break-induced replication (BIR) in Saccharomyces cerevisiae. Formation of a chromosome fragment by de novo telomere generation at one end of the linear vector and recombination-dependent replication of 100 kb of chromosomal sequences at the other end of the vector occurred at high frequency in wild-type strains. RAD51 was required for more than 95% of BIR events involving a single-end invasion and was essential when two BIR events were required for generation of a chromosome fragment. The similar genetic requirements for BIR and gene conversion suggest a common strand invasion intermediate in these two recombinational repair processes. Mutation of RAD50 or RAD59 conferred no significant defect in BIR in either RAD51 or rad51 strains. RAD52 was shown to be essential for BIR at unique chromosomal sequences, although rare recombination events were detected between the subtelomeric Y' repeats.

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Crossref · 10.1128/mcb.24.6.2344-2351.2004

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Metadata

Authors
Davis, A. P., & Symington, L. S.
Venue
Molecular and Cellular Biology
Published
2004-03
Volume
24
Issue
6
Pages
2344-2351
ISSN
  • 0270-7306 (ISSN-L)
  • 1098-5549
OpenAlex
W2157434667
Cited by
199
References
3
FWCI
4.70
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: RAD51 -Dependent Break-Induced Replication in Yeast. https://app.cochat.ai/papers/10.1128/mcb.24.6.2344-2351.2004
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Davis, A. P., & Symington, L. S. (2004). RAD51 -Dependent Break-Induced Replication in Yeast. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.24.6.2344-2351.2004

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