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Cited by 425

The DOI matches its Crossref record; 130 of the 130 references it cites were found in a registry or an index.

Messing with Bacterial Quorum Sensing

Open access
González, Juan E., Keshavan, Neela D.·2006·Microbiology and Molecular Biology Reviews

Abstract

SUMMARY: Quorum sensing is widely recognized as an efficient mechanism to regulate expression of specific genes responsible for communal behavior in bacteria. Several bacterial phenotypes essential for the successful establishment of symbiotic, pathogenic, or commensal relationships with eukaryotic hosts, including motility, exopolysaccharide production, biofilm formation, and toxin production, are often regulated by quorum sensing. Interestingly, eukaryotes produce quorum-sensing-interfering (QSI) compounds that have a positive or negative influence on the bacterial signaling network. This eukaryotic interference could result in further fine-tuning of bacterial quorum sensing. Furthermore, recent work involving the synthesis of structural homologs to the various quorum-sensing signal molecules has resulted in the development of additional QSI compounds that could be used to control pathogenic bacteria. The creation of transgenic plants that express bacterial quorum-sensing genes is yet another strategy to interfere with bacterial behavior. Further investigation on the manipulation of quorum-sensing systems could provide us with powerful tools against harmful bacteria.

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Metadata

Authors
González, J. E., & Keshavan, N. D.
Venue
Microbiology and Molecular Biology Reviews
Published
2006-12
Volume
70
Issue
4
Pages
859-875
ISSN
  • 1092-2172 (ISSN-L)
  • 1098-5557
OpenAlex
W2137724540
Cited by
425
References
130
FWCI
1.36
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Messing with Bacterial Quorum Sensing. https://app.cochat.ai/papers/10.1128/mmbr.00002-06
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González, J. E., & Keshavan, N. D. (2006). Messing with Bacterial Quorum Sensing. Microbiology and Molecular Biology Reviews. https://doi.org/10.1128/mmbr.00002-06

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