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Cited by 495

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Codon preferences in free-living microorganisms.

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Andersson, S G, Kurland, C G·1990·Microbiological Reviews

Abstract

A popular interpretation of the major codon preference is that it reflects the operation of a regulatory device that controls the expression of individual proteins. In this popular model, rapidly translated codons are thought to promote the accumulation of the highly expressed proteins and slowly translated codons are thought to retard the expression of poorly expressed proteins. However, this widely accepted model is not supported by kinetic theory or by experimental results. A less fashionable model in which the major codon preference has nothing to do with the expression level of the individual proteins is forwarded. In this model, the major codon preference is viewed as a global strategy to support the efficient function of the translation system and thereby to maximize the growth rates of cells under favorable conditions.

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Metadata

Authors
Andersson, S. G., & Kurland, C. G.
Venue
Microbiological Reviews
Published
1990
Volume
54
Issue
2
Pages
198-210
ISSN
0146-0749 (ISSN-L)
OpenAlex
W1777817130
Cited by
495
References
2
FWCI
10.81
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Codon preferences in free-living microorganisms. https://app.cochat.ai/papers/10.1128/mmbr.54.2.198-210.1990
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Andersson, S. G., & Kurland, C. G. (1990). Codon preferences in free-living microorganisms. Microbiological Reviews. https://doi.org/10.1128/mmbr.54.2.198-210.1990

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