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Tongue microbiota and oral health status in community-dwelling elderly adults.
Open accessAbstract
Aspiration of oral contents can lead to pneumonia, which is a major cause of death among elderly adults susceptible to swallowing impairments. Tongue microbiota are a dominant source of oral microbial populations that are ingested with saliva. This large-scale population-based study revealed variations in the tongue microbiota among community-dwelling elderly adults. The total bacterial density was independent of the conditions of teeth surrounding the tongue, whereas the microbiota composition, especially the relative abundances of predominant commensals, showed an association with tooth conditions. Our results demonstrate that the elderly with fewer teeth, poorer dental hygiene, and more dental caries experience constantly ingest more dysbiotic microbiota, which could be harmful for their respiratory health.
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“The tongue dorsum is one habitat niche of oral microbes, there the dominant microflora are Prevotella and Veillonella, which are associated with an increased risk of death due to pneumonia in older, frail patients (Asakawa et al., 2018; Kageyama et al., 2018).”
From Oral Microbiome and SARS-CoV-2: Beware of Lung Co-infection (2020) · cites this paper as Asakawa et al., 2018
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Metadata
- Authors
- Asakawa, M., Takeshita, T., Furuta, M., Kageyama, S., Takeuchi, K., Hata, J., Ninomiya, T., & Yamashita, Y.
- Affiliations
- Kyushu University (JP)
- Corresponding author
- Yamashita, Yoshihisa
- ORCID
- Venue
- mSphere
- Publisher
- American Society for Microbiology
- Published
- 2018-08-29
- Volume
- 3
- Issue
- 4
- ISSN
- 2379-5042 (ISSN-L)
- PMC
- PMC6094060
- OpenAlex
- W2885874599
- Cited by
- 113
- References
- 47
- Citations by year
- 2026: 8 · 2025: 12 · 2024: 14 · 2023: 8 · 2022: 13 · 2021: 22 · 2020: 24 · 2019: 12
- FWCI
- 16.63
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- mSphere (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Kyushu University Institutional Repository (QIR) (Kyushu University) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- MEXT | Japan Society for the Promotion of Science (16H05557, 16K15856, 16H02692, 16H05850)
- Topics
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Health Sciences › Dentistry › General Dentistry › Dental Health and Care Utilization
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- tongue microbiota, oral microbiota, community-dwelling older adults, oral health, aspiration, pneumonia, dysbiosis, tooth loss, dental caries, dental hygiene, commensal bacteria, respiratory health, swallowing impairment
- MeSH terms
- Aged, Bacteria, DNA, Bacterial, DNA, Ribosomal, Fungi, Humans, Japan, Oral Health, RNA, Ribosomal, 16S, Tongue, Cluster Analysis, Sequence Analysis, DNA, Independent Living, High-Throughput Nucleotide Sequencing, Real-Time Polymerase Chain Reaction, Microbiota
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