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Effect of continuous treatment with topical corticosteroid on episodic viral wheeze in preschool children.
Open accessAbstract
Acute episodic wheeze related to viral infections is a common and distressing condition and treatment remains unsatisfactory. Although some benefit from the continuous use of inhaled steroids has been demonstrated in young wheezy children, their effect primarily on acute episodes has not been considered. In this study the effect of budesonide (400 micrograms/day) was assessed in a four month double blind parallel trial, in 41 children (0.7-6.0 years) with predominantly episodic viral wheeze. Analysis of the last three months showed no difference between budesonide or placebo in mean daily total symptom score (median values 0.6 and 0.63), episode number (mean values 2.6 and 2.4), or score/episode (mean value 30 and 31). Four months of treatment with inhaled budesonide had no effect on acute episodes of wheeze in this group of children.
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Citations
Cited by
Preemptive Use of High-Dose Fluticasone for Virus-Induced Wheezing in Young Children
Ducharme, F. M., Lemire, C., Noya, F. J. D., Davis, G. M., Alos, N., Leblond, H., Savdie, C., Collet, J.-P., Khomenko, L., Rivard, G., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0808907 · Cited by 306
Bronchoalveolar lavage findings suggest two different forms of childhood asthma
STEVENSON, E. C., TURNER, G., HEANEY, L. G., SCHOCK, B. C., TAYLOR, R., GALLAGHER, T., ENNIS, M., & SHIELDS, M. D. (1997) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1997.tb01254.x · Cited by 272
Bacharier, L. B., Phillips, B. R., Zeiger, R. S., Szefler, S. J., Martinez, F. D., Lemanske, R. F., Sorkness, C. A., Bloomberg, G. R., Morgan, W. J., Paul, I. M., et al. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.09.029 · Cited by 270
New treatment regimes for virus-induced exacerbations of asthma
Edwards, M. R., Kebadze, T., Johnson, M. W., & Johnston, S. L. (2006) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2005.09.005 · Cited by 30
Metadata
- Authors
- Wilson, N., Sloper, K., & Silverman, M.
- Venue
- Archives of Disease in Childhood
- Publisher
- BMJ
- Published
- 1995-04-01
- Volume
- 72
- Issue
- 4
- Pages
- 317-320
- ISSN
- 0003-9888 (ISSN-L)
- 1468-2044
- OpenAlex
- W1974223115
- Cited by
- 162
- References
- 0
- FWCI
- 2.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Effect of continuous treatment with topical corticosteroid on episodic viral wheeze in preschool children. https://app.cochat.ai/papers/10.1136/adc.72.4.317
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- Wilson, N., Sloper, K., & Silverman, M. (1995). Effect of continuous treatment with topical corticosteroid on episodic viral wheeze in preschool children. Archives of Disease in Childhood. https://doi.org/10.1136/adc.72.4.317
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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