The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.
EULAR evidence-based recommendations for the management of fibromyalgia syndrome
Open accessAbstract
Objective To develop evidence-based recommendations for the management of fibromyalgia syndrome.Methods A multidisciplinary task force was formed representing 11 European countries. The design of the study, including search strategy, participants, interventions, outcome measures, data collection and analytical method, was defined at the outset. A systematic review was undertaken with the keywords "fibromyalgia", "treatment or management" and "trial". Studies were excluded if they did not utilise the American College of Rheumatology classification criteria, were not clinical trials, or included patients with chronic fatigue syndrome or myalgic encephalomyelitis. Primary outcome measures were change in pain assessed by visual analogue scale and fibromyalgia impact questionnaire. The quality of the studies was categorised based on randomisation, blinding and allocation concealment. Only the highest quality studies were used to base recommendations on. When there was insufficient evidence from the literature, a Delphi process was used to provide basis for recommendation.Results 146 studies were eligible for the review. 39 pharmacological intervention studies and 59 non-pharmacological were included in the final recommendation summary tables once those of a lower quality or with insufficient data were separated. The categories of treatment identified were antidepressants, analgesics, and "other pharmacological" and exercise, cognitive behavioural therapy, education, dietary interventions and "other non-pharmacological". In many studies sample size was small and the quality of the study was insufficient for strong recommendations to be made.Conclusions Nine recommendations for the management of fibromyalgia syndrome were developed using a systematic review and expert consensus.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Exercise interventions and psychological therapies, such as cognitive behavioural therapy (CBT), are examples of conservative treatments that are known to be effective for patients with chronic pain [5, 6, 9–12].”
From Exercise combined with Acceptance and Commitment Therapy (ExACT) compared to a supervised exercise programme for adults with chronic pain: study protocol for a randomised controlled trial. (2018) · cites this paper as [10]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Aerobic exercise, hydrotherapy, and multicomponent therapy have shown efficacy in alleviating fibromyalgic symptoms without harms, and can be offered to the patient either as alternative or used adjunctively with pharmacological therapy.7,8,30,33,41”
From Comparative Efficacy and Harms of Duloxetine, Milnacipran, and Pregabalin in Fibromyalgia Syndrome (2010) · cites this paper as [8]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The american college of rheumatology 1990 criteria for the classification of fibromyalgia
Wolfe, F., Smythe, H. A., Yunus, M. B., Bennett, R. M., Bombardier, C., Goldenberg, D. L., Tugwell, P., Campbell, S. M., Abeles, M., Clark, P., et al. (1990) · Arthritis & Rheumatism · doi:10.1002/art.1780330203 · Cited by 9,563
Downs, S. H., & Black, N. (1998) · Journal of Epidemiology and Community Health · doi:10.1136/jech.52.6.377 · Cited by 8,252
Clinical guidelines: Developing guidelines
Shekelle, P., Woolf, S. H., Eccles, M., & Grimshaw, J. (1999) · BMJ · doi:10.1136/bmj.318.7183.593 · Cited by 1,220
Management of fibromyalgia syndrome
Goldenberg, D. L. (2004) · JAMA · doi:10.1001/jama.292.19.2388 · Cited by 850
Rosnow, R. L., & Rosenthal, R. (1996) · Psychological Methods · doi:10.1037/1082-989x.1.4.331 · Cited by 761
Crofford, L. J., Rowbotham, M. C., Mease, P. J., Russell, I. J., Dworkin, R. H., Corbin, A. E., Young, J. P., LaMoreaux, L., Martin, S. A., Sharma, U., et al. (2005) · Arthritis & Rheumatism · doi:10.1002/art.20983 · Cited by 651
Arnold, L. M., Lu, Y., Crofford, L. J., Wohlreich, M., Detke, M. J., Iyengar, S., & Goldstein, D. J. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20485 · Cited by 624
Exercise for treating fibromyalgia syndrome
Busch, A. J., Barber, K. A. R., Overend, T. J., Peloso, P. M. J., & Schachter, C. L. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003786.pub2 · Cited by 619
Neurophysiologic evidence for a central sensitization in patients with fibromyalgia
Desmeules, J. A., Cedraschi, C., Rapiti, E., Baumgartner, E., Finckh, A., Cohen, P., Dayer, P., & VISCHER, T. L. (2003) · Arthritis & Rheumatism · doi:10.1002/art.10893 · Cited by 561
Mease, P. J. (2005) · PubMed · Cited by 528
Flagged first, then by citations
Research works printed but not linked: 1
- Heymann, 1998, A double-blinded, randomized, controlled study between amitrptyline and placebo in patients with fibromyalgia: analysis of the outcome measures, Rev Bras Reumatol, 38, 119
Cited by
Sorted by citations
Items 701–751 of 751
I.V. vitamin infusions for fibromyalgia provide little benefit
Golia, A., & Thornby, K. (2018) · Pharmacy Today · doi:10.1016/j.ptdy.2018.01.014
La fibromyalgie est-elle une maladie psychiatrique ? Is fibromyalgia a psychiatric illness?
Fond, G. B., Capdevielle, D., & Attal, J. (2011)
Effective Opioid Analgesic Alternatives and Approaches to Pain Management
Goesling, J., & Ilgen, M. A. (2019) · Current clinical psychiatry · doi:10.1007/978-3-030-16257-3_12
Pharmacological Interventions in Older Adults
Patel, J. J., Smith, D. W., Heafner, J., Christopher, N. G., & Grossberg, G. T. (2019) · Springer eBooks · doi:10.1007/978-3-030-10814-4_9
Effets d’un programme d’autogestion de la douleur chronique en contexte réel de pratique
Charland, A., Chevalier, L., Laroche, N., Véronneau, C., Duquette-Laplante, P., Naye, F., Tousignant‐Laflamme, Y., & Lagueux, É. (2019) · Kinésithérapie la Revue · doi:10.1016/j.kine.2019.08.011 · Cited by 2
Chronic Back Pain and Pain Science
Louw, A., & Butler, D. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-323-39370-6.00077-9
Pateron, D., Raphaël, M., & Trinh-Duc, A. (2016) · Méga-Guide Pratique des Urgences · doi:10.1016/b978-2-294-74748-9.00079-8
Kältetherapie bei Fibromyalgie
Kickmaier, S., & Hestmann, D. (2020) · rheuma plus · doi:10.1007/s12688-020-00382-y
El cuidado de la fibromialgia en la mujer y la importancia de la práctica deportiva
Falcón, J. H., & Alba‐Leonel, A. (2017) · Revista de Enfermería Neurológica · doi:10.37976/enfermeria.v16i1.235
Hansen, G. M. (2021) · UF Journal of Undergraduate Research · doi:10.32473/ufjur.v23i.128057
An RCT of a homeopathic package of care for fibromyalgia
(2009) · Focus on Alternative and Complementary Therapies · doi:10.1211/fact.14.3.0012
Chronic Fatigue and Postinfective Fatigue Syndromes
Lloyd, A. R. (2016) · ASM Press eBooks · doi:10.1128/9781555819439.ch18
FIBROMYALGIA: PRESENT AND FUTURE! WHERE WE STAND
Goswami, D., Sodhi, S. S., Vilochan, N., & Deswal, R. (2022) · INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH · doi:10.36106/ijsr/6201561
Puchner, R. J. (2012) · Springer eBooks · doi:10.1007/978-3-7091-1044-7_13
Mf, K. (2009) · EMC - AKOS - Trattato di Medicina · doi:10.1016/s1634-7358(09)70338-9
Vivian, D., & Bogduk, N. (2013) · Springer eBooks · doi:10.1007/978-3-642-28753-4_1500
Clinical Roundup: Selected Treatment Options for Chronic Musculoskeletal Pain
(2013) · Alternative and Complementary Therapies · doi:10.1089/act.2013.19104
Manske, R. C. (2011) · Elsevier eBooks · doi:10.1016/b978-0-323-05590-1.00016-4
Pateron, D., Raphaël, M., & Trinh-Duc, A. (2019) · Elsevier eBooks · doi:10.1016/b978-2-294-76093-8.00082-2
&NA; (2012) · Drugs & Therapy Perspectives · doi:10.2165/11608680-000000000-00000
Fibromyalgie : quel diagnostic, quel traitement ?
(2008) · Revue Francophone des Laboratoires · doi:10.1016/s1773-035x(08)74515-5
Häuser, W. (2010) · DoctorConsult - The Journal Wissen für Klinik und Praxis · doi:10.1016/j.dcjwkp.2010.06.006
&NA; (2010) · Drugs & Therapy Perspectives · doi:10.2165/11206190-000000000-00000
Puchner, R. J. (2010) · Springer eBooks · doi:10.1007/978-3-211-99713-0_14
Vallejo, M. Á., Rivera, J., & Vallejo-Slocker, L. (2021) · doi:10.2196/preprints.30207
Häuser, W., Thieme, K., Petzke, F. W., & Sommer, C. (2010) · doi:10.1002/9781444314380.ch11
(2012) · Drugs & Therapy Perspectives · doi:10.1007/bf03262135
Comorbidities and therapy for chronic non-specific low back pain and fibromyalgia
Nasonova, T. I., & Parfenova, E. V. (2022) · Neurology neuropsychiatry Psychosomatics · doi:10.14412/2074-2711-2022-3-26-31
Condiciones especiales en enfermedades reumáticas
Ortiz, B. O. A. (2021) · CID - Centro de Investigación y Desarrollo eBooks · doi:10.37811/cl_w798
Pateron, D., Raphaël, M., & Trinh-Duc, A. (2023) · Méga-Guide Pratique des Urgences · doi:10.1016/b978-2-294-78036-3.00087-7
Observational study of the effects of an osteopathic treatment for patients with fibromyalgia
Laroche, F., Bellan, E., Doléac, M., Meslé, R., Marty, M., & Rostaing, S. (2023) · Russian Osteopathic Journal · doi:10.32885/2220-0975-2023-3-124-138
Perfil epidemiológico de mulheres com Fibromialgia no extremo norte do Espírito Santo
Souza, H. R., Providello, M. S. L., Faustini, R. K., & da Silva, V. F. (2023) · Revista Cereus · doi:10.18605/2175-7275/cereus.v15n4p13-24
Pain makes me anxious, and anxiety gives me pain
Jackson, D., & Pal, S. (2024) · Cambridge University Press eBooks · doi:10.1017/9781108623872.017
A RELAÇÃO ENTRE A FIBROMIALGIA E A ESPIRITUALIDADE/RELIGIOSIDADE
Costa, L., Beatriz, J., Ferreira, J., & Carvalho, F. E. H. D. (2022) · Revista Educação e Saúde fundamentos e desafios · doi:10.29327/2192205.2.3-10
Evaluation of fibromyalgia in on-call healthcare workers
Özcan, F., Ünlü, Z., Aslantekin, Ş., & Erol, Ö. Ö. (2024) · Family practice and palliative care · doi:10.22391/fppc.1363910
Mazzucato‐Puchner, A., & Puchner, R. J. (2024) · Springer eBooks · doi:10.1007/978-3-662-69693-4_12
Hamdan, A., Sataloff, R. T., Hawkshaw, M. J., & Ghzayel, L. (2025) · Springer eBooks · doi:10.1007/978-3-031-97751-0_15
Tjeldnes, M. S., & Ekeland, A. (2013) · NORA - Norwegian Open Research Archives
Improving care for patients with rheumatic diseases
van Eijk‐Hustings, Y. (2014) · doi:10.26481/dis.20140313ye
Chronic Fatigue and Postinfective Fatigue Syndromes
Lloyd, A. R., Hickie, I. B., & Wakefield, D. (2009) · doi:10.1128/9781555815981.ch17
Effects of Pilates Exercises in Rheumatological Diseases
BEKAR, Z., & Oskay, D. (2026) · İzmir Katip Çelebi Üniversitesi Sağlık Bilimleri Fakültesi Dergisi · doi:10.61399/ikcusbfd.1695155
Downen, S. S., Farag, H., Davies, A., Okeke, C. M., Ben-Umeh, K. C., Yunusa, I. U., & Eguale, T. (2026) · JAMA Network Open · doi:10.1001/jamanetworkopen.2025.57536 · Cited by 1
Il dolore non legittimato : un’analisi della sindrome fibromialgica
Moretti, C. (2018) · theses.fr (ABES) · doi:10.70675/b4eaaa8cz395dz4a39zb037zfef2831ba835
Neuman, D. L., York, A., Gebre, M., Black, L. L., & Chadwick, A. L. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-45863-7.00099-8
Fitzcharles, M., & Ste‐Marie, P. A. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139152211.018
Utilizing Clinical Treatments with a Limited Evidence Base
Hsu, E., & Nedeljković, S. S. (2015) · Springer eBooks · doi:10.1007/978-3-319-15820-4_9
Bachasson, D. (2012) · theses.fr (ABES) · doi:10.70675/27c4344azf060z45f1za2a3z8fa3a86fee30
Metadata
- Authors
- Carville, S. F., Arendt-Nielsen, S., Bliddal, H., Blotman, F., Branco, J. C., Buskila, D., Da Silva, J. A. P., Danneskiold-Samsøe, B., Dincer, F., Henriksson, C., Henriksson, K. G., Kosek, E., Longley, K., McCarthy, G. M., Perrot, S., Puszczewicz, M., Sarzi-Puttini, P., Silman, A., Späth, M., & Choy, E. H.
- Affiliations
- King's College London (GB)
- Frederiksberg Hospital (DK)
- Hôpital Lapeyronie (FR)
- Hospital de Egas Moniz (PT)
- Soroka Medical Center (IL)
- Linköping University (SE)
- Linköping University Hospital (SE)
- Karolinska Institutet (SE)
- Mater Misericordiae University Hospital (IE)
- Hôpital Cochin (FR)
- Poznan University of Medical Sciences (PL)
- University of Manchester (GB)
- Corresponding author
- Carville, S F
- ORCID
- Venue
- Annals of the Rheumatic Diseases
- Publisher
- Elsevier BV
- Published
- 2008-04
- Volume
- 67
- Issue
- 4
- Pages
- 536-541
- ISSN
- 0003-4967 (ISSN-L)
- OpenAlex
- W2144915944
- Semantic Scholar
- 84b828205de2e816a68b107e5e03870f8d211480
- Cited by
- 752
- References
- 66
- Citations by year
- 2026: 3 · 2025: 8 · 2024: 9 · 2023: 17 · 2022: 18 · 2021: 10 · 2020: 21 · 2019: 17 · 2018: 22 · 2017: 28 · 2016: 48 · 2015: 45 · 2014: 52 · 2013: 70 · 2012: 83
- FWCI
- 44.21
- Type
- journal article
- Language
- en
- Update notices
- erratum (2015-02-01)
- Open access
- bronze
- doi.org
- Locations
- Annals of the Rheumatic Diseases (publishedVersion)
- PubMed (publishedVersion)
- Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (submittedVersion, other-oa)
- HighWire Press Open Archive (submittedVersion)
- Hacettepe University Institutional Repository (hacettepe.edu.tr) (submittedVersion, other-oa)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- VBN Forskningsportal (Aalborg Universitet) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Myofascial pain diagnosis and treatment
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Keywords
- fibromyalgia, fibromyalgia management, pharmacotherapy, antidepressants, analgesics, non-pharmacological treatment, exercise therapy, cognitive behavioral therapy, patient education, dietary intervention, pain intensity, Fibromyalgia Impact Questionnaire, chronic pain
- MeSH terms
- Analgesics, Opioid, Antidepressive Agents, Balneology, Fibromyalgia, Humans, Research Design, Tramadol, Evidence-Based Medicine
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
