Oral rehabilitation of children with ectodermal dysplasia
Open accessAbstract
The aim of this study was to describe the clinical treatment of young patients, affected by ectodermal dysplasia (ED), and to possibly establish clinical guidelines. The study design was case series. ED syndromes (EDs) are a heterogeneous group of inherited diseases characterised by abnormal development of tissues of ectodermal origin. The most common form of EDs is X linked hypohidrotic ED (HED). Characteristic triad of HED is oligo-anodontia, hypotricosis, hypo-anhydrosis. Oligo-anodontia is one of the most severe impairment, since it affects chewing, swallowing, speech, esthetics and social relation. Early prosthetic rehabilitation (at 2–3 years of age), with partial or complete dentures, is essential to improve oral function and reduce the social impairment.
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Four studies were identified from 1999 to 2023.
“N = 4 studies were identified from 1999 to 2023, two of which were conducted in the USA, and one study each in Australia and Italy, respectively.35,38”
From Dental Implants as a Treatment Option for Prosthetic Rehabilitation of Children with Ectodermal Dysplasia: A Systematic Review (2025) · cites this paper as [38]
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Prosthetic rehabilitation of patients with hypohidrotic ectodermal dysplasia: A systematic review
Schnabl, D., Grunert, I., Schmuth, M., & Kapferer‐Seebacher, I. (2018) · Journal of Oral Rehabilitation · doi:10.1111/joor.12638 · Cited by 63 · see citing works
“Early childhood - primary dentition Fifteen case reports (16, 22, 28, 30, 33-43) and six case series (21, 24, 44-47) reported on prosthetic rehabilitation of 38 individuals (37 males, one female) with HED in early childhood (Table 1).”
BackgroundSeremidi, K., Markouli, A., Agouropoulos, A., Polychronakis, N., & Gizani, S. (2022) · Case Reports in Dentistry · doi:10.1155/2022/9925475 · Cited by 6 · see citing works
“Patients and their parents should be included in the decision upon rehabilitation process, and they should be informed in advance about any possible risks, expected therapeutic outcomes, and financial requirements since the latter is a lifetime burden [3, 18, 19].”
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“38 All the studies were cohort observational studies, with two being prospective and two retrospective in nature.”
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- Authors
- Montanari, M., Callea, M., Battelli, F., & Piana, G.
- Affiliations
- University of Bologna (IT)
- IRCCS Materno Infantile Burlo Garofolo (IT)
- Corresponding author
- Callea, Michele
- Venue
- BMJ Case Reports
- Publisher
- BMJ
- Published
- 2012-06-22
- Volume
- 2012
- Pages
- bcr0120125652
- ISSN
- 1757-790X (ISSN-L)
- PMC
- PMC3387443
- OpenAlex
- W1974353759
- Cited by
- 26
- References
- 22
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 2 · 2022: 4 · 2021: 1 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 1 · 2015: 3 · 2014: 3 · 2013: 1
- FWCI
- 1.03
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- BMJ Case Reports (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › dental development and anomalies
- Health Sciences › Health Professions › Speech and Hearing › Oral and Craniofacial Lesions
- Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
- Keywords
- ectodermal dysplasia, hypohidrotic ectodermal dysplasia, oligodontia, tooth agenesis, children, oral rehabilitation, partial dentures, complete dentures, clinical guidelines, oral function
- MeSH terms
- Child, Child, Preschool, Denture, Complete, Denture, Partial, Esthetics, Dental, Humans, Male, Mastication, Speech, Ectodermal Dysplasia 1, Anhidrotic
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