Dental implants in patients with ectodermal dysplasia and tooth agenesis: A critical review of the literature
Abstract
Purpose The aims of this article are to critique the available literature on dental implants in patients with ectodermal dysplasia (ED) syndrome and tooth agenesis, review the outcomes of implant therapy in these patients, and provide recommendations on the timing of implant placement for these patients. Materials and methods Searches were performed using Medline, Embase, All EBM Reviews, and Pre-Medline for articles relating to implant patients suffering from ED. Articles unrelated to the topic of dental implants in patients with ED and tooth agenesis, without abstracts, or in languages other than English were excluded. Selected articles were graded according to levels of evidence based upon guidelines set forth by the Agency for Health Care Policy and Research. Articles found to have a level of evidence of IV were excluded from this study. Results The literature on dental implants in patients with ED and tooth agenesis was found to be scarce. No randomized controlled or case-controlled studies were found. Only 12 articles were found to satisfy all inclusion criteria. Conclusion Implant survival rates vary between 88.5% and 97.6% in patients with ED and between 90% and 100% in patients with tooth agenesis. Implants placed in adolescent ED patients do not have a significant effect on craniofacial growth, while implants placed in ED patients younger than 18 years have a higher risk of failure.
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Replacement of full or overdentures is typically required every 1 to 3 years, while partial dentures may need to be renewed within 1 to 6 years.
“Replacement of full or overdentures is typically required every 1 to 3 years, while partial dentures may need to be renewed within 1 to 6 years, emphasizing the importance of regular follow-up and long-term maintenance planning in pediatric patients [7,22].”
From Application of a Conservative Prosthodontic Approach in the Rehabilitation of a 10-Year-Old Child with Hypohidrotic Ectodermal Dysplasia (2025) · cites this paper as [22]
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- Authors
- Yap, A. K. W., & Klineberg, I. J.
- Affiliations
- The University of Sydney (AU)
- ORCID
- Iven J Klineberg
- Venue
- The Journal of Prosthetic Dentistry
- Publisher
- Elsevier BV
- Published
- 2010-08
- Volume
- 104
- Issue
- 2
- Pages
- 97
- ISSN
- 0022-3913 (ISSN-L)
- OpenAlex
- W1566262796
- Cited by
- 75
- References
- 16
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 6 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 6 · 2018: 5 · 2017: 5 · 2016: 5 · 2015: 6 · 2014: 9 · 2013: 3 · 2012: 9
- FWCI
- 6.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Prosthetic Dentistry (publishedVersion)
- PubMed (publishedVersion)
- The Sydney eScholarship Repository (The University of Sydney) (submittedVersion)
- Topics
- Health Sciences › Dentistry › Oral Surgery › Dental Implant Techniques and Outcomes
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › dental development and anomalies
- Health Sciences › Health Professions › Emergency Medical Services › Dental Trauma and Treatments
- Keywords
- dental implants, ectodermal dysplasia, tooth agenesis, implant survival, implant failure, implant placement timing, craniofacial growth, adolescents, implant outcomes
- MeSH terms
- Adolescent, Age Factors, Anodontia, Child, Ectodermal Dysplasia, Humans, Dental Implants, Survival Analysis, Case-Control Studies, Randomized Controlled Trials as Topic, Treatment Outcome, Evidence-Based Dentistry
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