The acute phase response and exercise: court and field sports
Open accessAbstract
Objective—To determine the presence or absence of an acute phase response after training for court and field sports. Participants—All members of the Australian women's soccer team (n = 18) and all members of the Australian Institute of Sport netball team (n = 14). Methods—Twelve acute phase reactants (white blood cell count, neutrophil count, platelet count, serum iron, ferritin, and transferrin, percentage transferrin saturation, α 1 antitrypsin, caeruloplasmin, α 2 acid glycoprotein, C reactive protein, and erythrocyte sedimentation rate) were measured during a rest period and after moderate and heavy training weeks in members of elite netball and women's soccer teams. Results—Responses consistent with an acute phase response were found in five of 24 tests in the soccer players, and in three of 24 tests in the netball players. Responses in the opposite direction were found in seven of 24 tests in the soccer players and two of 24 tests in the netballers. The most sensitive reactant measured, C reactive protein, did not respond in a manner typical of an acute phase response. Conclusion—An acute phase response does not seem to occur as a consequence of the levels of training typical of elite female netball and soccer teams. This has implications for the interpretation of biochemical variables in these groups.
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Cross-sectional studies demonstrate an association between physical inactivity and low-grade systemic inflammation in healthy subjects, elderly people, and patients with intermittent claudication.
“Cross-sectional studies demonstrate an association between physical inactivity and low-grade systemic inflammation in healthy subjects [71–75], in elderly people [76, 77], and in patients with intermittent claudication [78].”
From Exercise as a Mean to Control Low‐Grade Systemic Inflammation (2008) · cites this paper as [74]
Longitudinal studies show that regular training induces a reduction in CRP level, suggesting that physical activity as such may suppress systemic low-grade inflammation.
“Moreover, the finding in longitudinal studies that regular training induces a reduction in CRP level suggests that the physical activity as such may suppress systemic low-grade inflammation [74, 75, 79, 80].”
From Exercise as a Mean to Control Low‐Grade Systemic Inflammation (2008) · cites this paper as [74]
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- Authors
- Fallon, K. E., Fallon, S. K., & Boston, T.
- Affiliations
- Australian Sports Commission (AU)
- Corresponding author
- Fallon, K E
- Fallon, S K
- Venue
- British Journal of Sports Medicine
- Publisher
- BMJ
- Published
- 2001-06
- Volume
- 35
- Issue
- 3
- Pages
- 170-173
- ISSN
- 0306-3674 (ISSN-L)
- 1473-0480
- PMC
- PMC1724337
- OpenAlex
- W2067474989
- Cited by
- 122
- References
- 21
- Citations by year
- 2026: 3 · 2024: 3 · 2023: 3 · 2022: 2 · 2021: 2 · 2020: 2 · 2018: 4 · 2017: 6 · 2016: 3 · 2015: 6 · 2014: 7 · 2013: 9 · 2012: 14
- FWCI
- 2.80
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- British Journal of Sports Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports injuries and prevention
- Keywords
- acute phase response, acute phase proteins, C-reactive protein, netball, women's football, elite female athletes, field sports, serum iron, ferritin, transferrin, ceruloplasmin, alpha-1-antitrypsin, erythrocyte sedimentation rate, white blood cell count, neutrophil count, platelet count, training load
- MeSH terms
- Acute-Phase Reaction, Adolescent, Adult, Female, Humans, Prospective Studies, Surveys and Questionnaires, Soccer, Sports, Exercise
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