The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Long-term Treatment of Galactorrhoea and Hypogonadism with Bromocriptine
Open accessAbstract
Seventeen women and four men with galactorrhoea and associated hypogonadism have been treated with bromocriptine for 2 to 28 months. In 18 patients the gonadal status became normal as the galactorrhoea improved. The gonadally unresponsive patients had either pituitary tumours or premature menopause. Prolactin levels fell with treatment; withdrawal of the drug was associated with an increase in serum prolactin and a recurrence of the galactorrhoea and hypogonadism. Two patients tried to become pregnant on treatment and both succeeded. Raised prolactin levels appear to block the actions of the gonadotrophins at a gonadal level rather than prevent their synthesis or release; lowering prolactin secretion with bromocriptine allows resumption of normal gonadal function. Bromocriptine appears to be the treatment of choice for inappropriate lactation in association with hypogonadism on a long-term basis.
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Cites
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Self-citationLevodopa Suppression of Prolactin in Nonpuerperal Galactorrhea
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Cited by
REVIEW ARTICLE: THE POLYCYSTIC OVARY SYNDROME
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Adrenocortical function in hyperprolactinemic women
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Prolactin modulation of dehydroepiandrosterone sulfate secretion
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Bone Marker and Bone Density Responses to Dopamine Agonist Therapy in Hyperprolactinemic Males
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PLASMA ANDROGENS IN WOMEN WITH HYPERPROLACTINAEMIC AMENORRHOES
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Metadata
- Authors
- Thorner, M. O., McNeilly, A. S., Hagan, C., & Besser, G. M.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1974-05-25
- Volume
- 2
- Issue
- 5916
- Pages
- 419-422
- ISSN
- 0007-1447 (ISSN-L)
- 1468-5833
- OpenAlex
- W2034958855
- Cited by
- 406
- References
- 17
- FWCI
- 34.86
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Thorner, M. O., McNeilly, A. S., Hagan, C., & Besser, G. M. (1974). Long-term Treatment of Galactorrhoea and Hypogonadism with Bromocriptine. BMJ. https://doi.org/10.1136/bmj.2.5916.419
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.