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Cited by 406

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Long-term Treatment of Galactorrhoea and Hypogonadism with Bromocriptine

Open access
Thorner, M. O., McNeilly, A. S., Hagan, C., Besser, G. M.·1974·BMJ

Abstract

Seventeen women and four men with galactorrhoea and associated hypogonadism have been treated with bromocriptine for 2 to 28 months. In 18 patients the gonadal status became normal as the galactorrhoea improved. The gonadally unresponsive patients had either pituitary tumours or premature menopause. Prolactin levels fell with treatment; withdrawal of the drug was associated with an increase in serum prolactin and a recurrence of the galactorrhoea and hypogonadism. Two patients tried to become pregnant on treatment and both succeeded. Raised prolactin levels appear to block the actions of the gonadotrophins at a gonadal level rather than prevent their synthesis or release; lowering prolactin secretion with bromocriptine allows resumption of normal gonadal function. Bromocriptine appears to be the treatment of choice for inappropriate lactation in association with hypogonadism on a long-term basis.

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Crossref · 10.1136/bmj.2.5916.419

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Metadata

Authors
Thorner, M. O., McNeilly, A. S., Hagan, C., & Besser, G. M.
Venue
BMJ
Publisher
BMJ
Published
1974-05-25
Volume
2
Issue
5916
Pages
419-422
ISSN
  • 0007-1447 (ISSN-L)
  • 1468-5833
OpenAlex
W2034958855
Cited by
406
References
17
FWCI
34.86
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Long-term Treatment of Galactorrhoea and Hypogonadism with Bromocriptine. https://app.cochat.ai/papers/10.1136/bmj.2.5916.419
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Thorner, M. O., McNeilly, A. S., Hagan, C., & Besser, G. M. (1974). Long-term Treatment of Galactorrhoea and Hypogonadism with Bromocriptine. BMJ. https://doi.org/10.1136/bmj.2.5916.419

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