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Cited by 255

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Severity of coronary atherosclerosis related to lipoprotein concentration.

Open access
Jenkins, P J, Harper, R W, Nestel, P J·1978·BMJ

Abstract

The influence of individual lipoproteins on the severity of coronary atherosclerosis was studied in 41 patients undergoing coronary angiography. The extent of athero-sclerosis was quantified by a coronary atherosclerosis score (CAS) based on the number and severity of lesions in eight proximal segments of the coronary circulation. The concentration of high-density lipoprotein (HDL) showed a strong inverse association with CAS, which was independent of the effects of age and other lipoproteins. On multivariate analysis concentrations of other lipids--namely, total plasma cholesterol, low-density lipoprotein (LDL) cholesterol, and the combined effect of LDL cholesterol plus very-low-density lipoprotein triglyceride--showed direct, significant correlations with CAS, but these were weaker than that of HDL. This study shows that concentrations of several circulating lipoproteins are related to the severity of coronary atherosclerosis, HDL having an apparent retarding effect. These findings may partly explain the influence of lipoproteins on the development of clinical coronary heart disease.

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Metadata

Authors
Jenkins, P. J., Harper, R. W., & Nestel, P. J.
Venue
BMJ
Publisher
BMJ
Published
1978-08-05
Volume
2
Issue
6134
Pages
388-391
ISSN
  • 0007-1447 (ISSN-L)
  • 1468-5833
OpenAlex
W2065438730
Cited by
255
References
11
FWCI
30.01
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Severity of coronary atherosclerosis related to lipoprotein concentration. https://app.cochat.ai/papers/10.1136/bmj.2.6134.388
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Jenkins, P. J., Harper, R. W., & Nestel, P. J. (1978). Severity of coronary atherosclerosis related to lipoprotein concentration. BMJ. https://doi.org/10.1136/bmj.2.6134.388

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.