The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Converting enzyme inhibition and kidney function in normotensive diabetic patients with persistent microalbuminuria.
Open accessAbstract
The effects of a long term reduction in blood pressure on the kidney function of normotensive diabetic patients who had persistent microalbuminuria (30-300 mg albumin/24 hours) were studied in two groups of 10 such patients before and during six months of treatment with either 20 mg enalapril or placebo daily. Treatments were assigned randomly in a double blind fashion. Before treatment both groups had similar clinical characteristics, weight, diet, total glycosylated haemoglobin, median albumin excretion rate (enalapril group 124 mg/24 h, placebo group 81 mg/24 h), and mean arterial pressure (enalapril group 100 (SD 8) mm Hg, placebo group 99 (6) mm Hg). During treatment weight, urinary urea excretion, and total glycosylated haemoglobin remained unchanged. The mean arterial pressure decreased in the enalapril group but not in the placebo group (enalapril group 90 (10) mm Hg, placebo group 98 (8) mm Hg). The median albumin excretion rate also fell in the enalapril group but not in the placebo group (enalapril group 37 mg/24 h, placebo group 183 mg/24 h.) The glomerular filtration rate rose in the enalapril group from 130 (23) ml/min/1.73 m2 to 141 (24) ml/min/1.73 m2, and total renal resistances and fractional albumin clearance decreased while fractional albumin clearance increased in the placebo group. These results show that in patients who have diabetes but not hypertension a reduction in blood pressure by inhibition of converting enzyme for six months can reduce persistent microalbuminuria, perhaps by decreasing the intraglomerular pressure.
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Cites
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Microalbuminuria Predicts Clinical Proteinuria and Early Mortality in Maturity-Onset Diabetes
Mogensen, C. E. (1984) · New England Journal of Medicine · doi:10.1056/nejm198402093100605 · Cited by 1,908
MICROALBUMINURIA AS A PREDICTOR OF CLINICAL NEPHROPATHY IN INSULIN-DEPENDENT DIABETES MELLITUS
Viberti, G. C., Jarrett, R. J., Mahmud, U., Hill, R. D., Argyropoulos, A., & Keen, H. (1982) · The Lancet · doi:10.1016/s0140-6736(82)92450-3 · Cited by 1,663
Predicting Diabetic Nephropathy in Insulin-Dependent Patients
Mogensen, C. E., & Christensen, C. K. (1984) · New England Journal of Medicine · doi:10.1056/nejm198407123110204 · Cited by 1,569
Zatz, R., Dunn, B. R., Meyer, T. W., Anderson, S., Rennke, H. G., & Brenner, B. M. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112521 · Cited by 1,209
Diabetes and Glucose Tolerance as Risk Factors for Cardiovascular Disease: The Framingham Study
Kannel, W. B., & McGee, D. L. (1979) · Diabetes Care · doi:10.2337/diacare.2.2.120 · Cited by 1,203
Diabetic nephropathy in type 1 (insulin-dependent) diabetes: An epidemiological study
Andersen, A. R., Christiansen, J. S., Andersen, J. K., Kreiner, S., & Deckert, T. (1983) · Diabetologia · doi:10.1007/bf00284458 · Cited by 1,067
The Stages in Diabetic Renal Disease: With Emphasis on the Stage of Incipient Diabetic Nephropathy
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Parving, H.-H., Smidt, U., Andersen, A., & Svendsen, P. (1983) · The Lancet · doi:10.1016/s0140-6736(83)92462-5 · Cited by 867
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Cited by
Ahmed, A., Jorna, T., & Bhandari, S. (2016) · Nephron · doi:10.1159/000447068 · Cited by 11,717
KDIGO 2020 Clinical practice guideline for diabetes management in chronic kidney disease
de Boer, I. H., Caramori, M. L., Chan, J. C. N., Heerspink, H. J. L., Hurst, C., Khunti, K., Liew, A., Michos, E. D., Navaneethan, S. D., Olowu, W. A., et al. (2020) · Kidney International · doi:10.1016/j.kint.2020.06.019 · Cited by 1,399
KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease
Rossing, P., Caramori, M. L., Chan, J. C. N., Heerspink, H. J. L., Hurst, C., Khunti, K., Liew, A., Michos, E. D., Navaneethan, S. D., Olowu, W. A., et al. (2022) · Kidney International · doi:10.1016/j.kint.2022.06.008 · Cited by 1,373
MICROALBUMINURIA AS PREDICTOR OF VASCULAR DISEASE IN NON-DIABETIC SUBJECTS
Yudkin, J., Forrest, R., & Jackson, C. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92657-8 · Cited by 847
Strippoli, G. F., Bonifati, C., Craig, M. E., Navaneethan, S. D., & Craig, J. C. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006257 · Cited by 265
Metadata
- Authors
- Marre, M., Leblanc, H., Suarez, L., Guyenne, T. T., Menard, J., & Passa, P.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1987-06-06
- Volume
- 294
- Issue
- 6585
- Pages
- 1448-1452
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2069375794
- Cited by
- 261
- References
- 32
- FWCI
- 32.17
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Marre, M., Leblanc, H., Suarez, L., Guyenne, T. T., Menard, J., & Passa, P. (1987). Converting enzyme inhibition and kidney function in normotensive diabetic patients with persistent microalbuminuria. BMJ. https://doi.org/10.1136/bmj.294.6585.1448
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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