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When to stop a clinical trial.
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When to
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“However, these decisions are rarely straightforward, and there is a different threshold for stopping a trial in the case of potential harm than in the case of benefit [17].”
From The recording of adverse events from psychological treatments in clinical trials: evidence from a review of NIHR-funded trials (2014) · cites this paper as [17]
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Citations
Cites
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Metadata
- Authors
- Pocock, S. J.
- Affiliations
- London School of Hygiene & Tropical Medicine (GB)
- Corresponding author
- Pocock, S. J.
- ORCID
- Pocock, S. J.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1992-07-25
- Volume
- 305
- Issue
- 6847
- Pages
- 235-240
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- PMC
- PMC1882707
- OpenAlex
- W1968817382
- Cited by
- 255
- References
- 21
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 5 · 2022: 5 · 2021: 5 · 2020: 3 · 2019: 10 · 2018: 4 · 2017: 6 · 2016: 12 · 2015: 10 · 2014: 20 · 2013: 8 · 2012: 12
- FWCI
- 10.53
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- BMJ (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Keywords
- clinical trial termination, stopping rules, trial ethics
- MeSH terms
- Clinical Trials as Topic, Data Interpretation, Statistical, Decision Making, Ethics, Medical, Risk Assessment, Information Dissemination, Editorial Policies, Uncertainty, Therapeutic Human Experimentation
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