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Cited by 511

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Case-control study of migraine and risk of ischaemic stroke in young women

Open access
Tzourio, Christophe, Tehindrazanarivelo, Alain, Iglesias, Serge, Alperovitch, Annick, Chedru, Francois, d'Anglejan-Chatillon, Jacques, Bousser, Marie-Germaine·1995·BMJ

Abstract

Objective : To determine whether migraine is a risk factor for ischaemic stroke in young women. Design : A case-control study. Setting : Five hospitals in Paris and suburbs. Subjects : 72 women aged under 45 with ischaemic stroke and 173 controls randomly selected from women hospitalised in the same centres. Main outcome measures : Ischaemic stroke confirmed by cerebral computerised tomography or magnetic resonance imaging; history of headache recorded with structured interview, and diagnosis of migraine assessed by reproducibility study. Results : Ischaemic stroke was strongly associated with migraine, both migraine without aura (odds ratio 3.0 (95% confidence interval 1.5 to 5.8)) and migraine with aura (odds ratio 6.2 (2.1 to 18.0)). The risk of ischaemic stroke was substantially increased for migrainous women who were using oral contraceptives (odds ratio 13.9) or who were heavy smokers (>/=20 cigarettes/day) (odds ratio 10.2). Conclusions : These results indicate an independent association between migraine and the risk of ischaemic stroke in young women. Although the absolute risk of ischaemic stroke in young women with migraine is low, the reduction of known risk factors for stroke, in particular smoking and use of oral contraceptives, should be considered in this group.

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Crossref · 10.1136/bmj.310.6983.830

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Metadata

Authors
Tzourio, C., Tehindrazanarivelo, A., Iglesias, S., Alperovitch, A., Chedru, F., d'Anglejan-Chatillon, J., & Bousser, M.-G.
Venue
BMJ
Publisher
BMJ
Published
1995-04-01
Volume
310
Issue
6983
Pages
830-833
ISSN
  • 0007-1447 (ISSN-L)
  • 0959-8138
  • 1468-5833
OpenAlex
W2074538974
Cited by
511
References
1
FWCI
8.73
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Case-control study of migraine and risk of ischaemic stroke in young women. https://app.cochat.ai/papers/10.1136/bmj.310.6983.830
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Tzourio, C., Tehindrazanarivelo, A., Iglesias, S., Alperovitch, A., Chedru, F., d'Anglejan-Chatillon, J., & Bousser, M.-G. (1995). Case-control study of migraine and risk of ischaemic stroke in young women. BMJ. https://doi.org/10.1136/bmj.310.6983.830

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