Comparative efficacy of three mumps vaccines during disease outbreak in Eastern Switzerland: cohort study
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sonality, communication skills, and interest in medical topics are assessed and scored.Offers are made to the 260 interviewees with the top scores.In 1997, 2701 candidates from the United Kingdom and the rest of the European Union applied to Nottingham through the Universities Colleges and Admission Service.The decision for each applicant was noted along with ethnic group, sex, and stage of the process.Statistical comparison of frequencies was by 2 test with Yates's correction.Significantly more non-white and male applicants were rejected at the academic and questionnaire stages, whereas significantly more white and female applicants were rejected at the statement review and interview stages (table).The net effect was that significantly more white and female applicants were offered a place.
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In Schlegel 1999, the Rubini strain-containing MMR vaccine estimate against mumps was not statistically relevant (VE -4%; 95% CI 218 to 15).
“the estimate from the Schlegel 1999 study was not statistically relevant (VE -4%; 95% CI 218 to 15)”
From Vaccines for measles, mumps and rubella in children (2012) · cites this paper as Schlegel 1999
The vaccine-efficacy table (Additional information) reports a Rubini estimate of −4%, with P=1.00, supporting the statement that the estimate was not statistically significant. But the printed confidence interval omits the minus sign: the paper reports −218 to 15, not 218 to 15. (LLM, conf=0.90)
Experimental — accuracy not yet measuredIn a retrospective cohort in Switzerland, MMR vaccine containing Rubini mumps strain had a vaccine effectiveness of -4% (95% CI -218 to 15) for at least one dose.
“VE = -4% (-218 to 15) for at least 1 dose”
From Vaccines for measles, mumps and rubella in children (2012) · cites this paper as Schlegel 1999
For at least one dose of Jeryl Lynn strain-containing MMR vaccine, vaccine effectiveness against mumps was 80.7% (95% CI 57.8 to 90.8) in Ong 2005 and 78% (95% CI 64 to 82) in Schlegel 1999.
“VE 80.7%; 95% CI 57.8 to 90.8 (Ong 2005) and 78% (95% CI 64 to 82) (Schlegel 1999)”
From Vaccines for measles, mumps and rubella in children (2012) · cites this paper as Schlegel 1999
For at least one dose of MMR Urabe vaccine, vaccine effectiveness against mumps was 87% (95% CI 76 to 94) in Schlegel 1999.
“Effectiveness of MMR Urabe vaccine (at least one dose) has been estimated to be highly effective (VE 87%; 95% CI 76 to 94) in Schlegel 1999”
From Vaccines for measles, mumps and rubella in children (2012) · cites this paper as Schlegel 1999
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Cites
Expanded Programme on Immunization
Kassianos, G. C. (2001) · doi:10.1002/9780470693841.ch8 · Cited by 397 · see citing works
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Immunisation and herd immunity
Anderson, R. M., & May, R. M. (1990) · The Lancet · doi:10.1016/0140-6736(90)90420-a · Cited by 328 · see citing works
An Outbreak of Mumps in a Population Partially Vaccinated with the Rubini Strain
Germann, D., Ströhle, A., Eggenberger, K., et al. (1996) · Scandinavian Journal of Infectious Diseases · doi:10.3109/00365549609027163 · Cited by 62 · see citing works
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Vaccines for measles, mumps and rubella in children
Demicheli, V., Rivetti, A., Debalini, M. G., & Di Pietrantonj, C. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004407.pub3 · Cited by 372 · see citing works
Vaccine effectiveness estimates, 2004-2005 mumps outbreak, England
Cohen, C., White, J. M., Savage, E. J., Glynn, J. R., Choi, Y., Andrews, N., Brown, D., & Ramsay, M. E. (2007) · Emerging infectious diseases · doi:10.3201/eid1301.060649 · Cited by 241 · see citing works
The effectiveness of the mumps component of the MMR vaccine: a case control study
Harling, R., White, J. M., Ramsay, M. E., Macsween, K. F., & Bosch, C. V. D. (2005) · Vaccine · doi:10.1016/j.vaccine.2004.10.020 · Cited by 132 · see citing works
Comparative efficacy of Rubini, Jeryl-Lynn and Urabe mumps vaccine in an Asian population
Ong, G., Goh, K. T., Ma, S., & Chew, S. K. (2005) · Journal of Infection · doi:10.1016/j.jinf.2004.10.001 · Cited by 50 · see citing works
- Authors
- Schlegel, M., Osterwalder, J. J., Galeazzi, R. L., & Vernazza, P. L.
- Affiliations
- Kantonsspital St. Gallen (CH)
- Corresponding author
- Vernazza, P. L
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1999-08-07
- Volume
- 319
- Issue
- 7206
- Pages
- 352-352
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- PMC
- PMC32261
- OpenAlex
- W2022910857
- Cited by
- 56
- References
- 6
- Citations by year
- 2024: 1 · 2023: 1 · 2021: 2 · 2020: 4 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 2 · 2015: 2 · 2014: 1 · 2013: 2 · 2012: 1
- FWCI
- 2.73
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- BMJ (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Social Sciences › Health › Vaccine Coverage and Hesitancy
- Keywords
- mumps vaccine, vaccine efficacy, mumps outbreak, vaccine comparison, East Switzerland
- MeSH terms
- Adolescent, Child, Child, Preschool, Disease Outbreaks, Humans, Mumps, Mumps Vaccine, Risk Factors, Switzerland, Cohort Studies, Treatment Outcome
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