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Ronksley and colleagues asserted that the association between moderate alcohol consumption and reduced mortality risk was “beyond question.”1 We reviewed all 67 studies that generated the 84 articles in their meta-analysis. All but two had at least one of six serious methodological problems, and these two had mixed findings (figure⇓); see http://carbc.ca/Portals/0/News/FeatureSupplement201203.pdf for bibliography).
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Beneficial effects of non-heavy drinking on ischaemic diseases have been put into question for different reasons.
“While these beneficial effects have been put into question for different reasons (e.g. 174, 258, 259), and while they may be overestimated using standard epidemiological methodology because of biased comparison groups 260, biological pathways corroborate some protective effect.”
From The relationship between different dimensions of alcohol use and the burden of disease—an update (2017) · cites this paper as [258]
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Cites
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Research works printed but not linked: 2
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Authors' reply to Stockwell and colleagues
Ronksley, P. E., Brien, S., Turner, B. J., Mukamal, K. J., & Ghali, W. A. (2012) · BMJ · doi:10.1136/bmj.e2294
Alcohol and Cardiovascular Risk
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- Authors
- Stockwell, T., Greer, A., Fillmore, K., Chikritzhs, T., & Zeisser, C.
- Affiliations
- University of Victoria (CA)
- University of Toronto (CA)
- Institute for Scientific Analysis (US)
- Curtin University (AU)
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2012-03-27
- Volume
- 344
- Issue
- mar27 2
- Pages
- e2276-e2276
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2019716439
- Cited by
- 53
- References
- 3
- Citations by year
- 2024: 3 · 2023: 1 · 2022: 1 · 2021: 4 · 2020: 1 · 2019: 2 · 2018: 5 · 2017: 4 · 2016: 9 · 2015: 8 · 2014: 3 · 2013: 7 · 2012: 5
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- cc-by
- Locations
- BMJ (publishedVersion)
- PubMed (publishedVersion)
- eSpace (Curtin University) (submittedVersion, cc-by)
- eSpace (Curtin University) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Keywords
- moderate drinking, mortality risk, meta-analysis critique, methodological errors, health effects of alcohol
- MeSH terms
- Alcohol Drinking, Cardiovascular Diseases, Humans
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