The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Analysis of matched case-control studies
Open accessAbstract
There are two common misconceptions about case-control studies: that matching in itself eliminates (controls) confounding by the matching factors, and that if matching has been performed, then a “matched analysis” is required. However, matching in a case-control study does not control for confounding by the matching factors; in fact it can introduce confounding by the matching factors even when it did not exist in the source population. Thus, a matched design may require controlling for the matching factors in the analysis. However, it is not the case that a matched design requires a matched analysis. Provided that there are no problems of sparse data, control for the matching factors can be obtained, with no loss of validity and a possible increase in precision, using a “standard” (unconditional) analysis, and a “matched” (conditional) analysis may not be required or appropriate.
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Metadata
- Authors
- Pearce, N.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2016-02-25
- Volume
- 352
- Pages
- i969
- ISSN
- 1756-1833 (ISSN-L)
- OpenAlex
- W2281397941
- Cited by
- 771
- References
- 20
- FWCI
- 62.65
- Type
- journal article
- Language
- en
- Open access
- hybrid
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