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Alternative approaches for confounding adjustment in observational studies using weighting based on the propensity score: a primer for practitioners
Open accessAbstract
This report aims to provide methodological guidance to help practitioners select the most appropriate weighting method based on propensity scores for their analysis out of many available options (eg, inverse probability treatment weights, standardised mortality ratio weights, fine stratification weights, overlap weights, and matching weights), and outlines recommendations for transparent reporting of studies using weighting based on the propensity scores.
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“Within each cohort, we used propensity score fine stratification weighting to account for confounding.33”
From Glucagon-like peptide-1 receptor agonists and risk of suicidality among patients with type 2 diabetes: active comparator, new user cohort study (2025) · cites this paper as [33]
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“In addition, several authors have reported the development of depression and other comorbidities in prostate cancer patients treated with androgen deprivation therapy.48,49”
From Mindfulness-based interventions for psychological wellbeing and quality of life in men with prostate cancer: A systematic review and meta-analysis (2021) · cites this paper as [49]
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The central role of the propensity score in observational studies for causal effects
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- Desai, 2019, An empirical evaluation of a propensity score stratification based weighting approach in settings of more than two treatment groups, Pharmacoepidemiol Drug Saf, 28, 19
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Metadata
- Authors
- Desai, R. J., & Franklin, J. M.
- Affiliations
- Brigham and Women's Hospital (US)
- Corresponding author
- Desai, Rishi J
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2019-10-23
- Volume
- 367
- Pages
- l5657
- ISSN
- 1756-1833 (ISSN-L)
- 0959-8138
- OpenAlex
- W2982188023
- Cited by
- 657
- References
- 31
- Citations by year
- 2026: 76 · 2025: 142 · 2024: 117 · 2023: 108 · 2022: 108 · 2021: 78 · 2020: 26
- FWCI
- 41.26
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.bmj.com/company/legal-information/terms-conditions/legal-information/tdm-licencepolicy (tdm)
- Locations
- BMJ (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- Brigham and Women's Hospital
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Keywords
- propensity score weighting, confounding adjustment, observational studies, reporting transparency, causal inference
- MeSH terms
- Data Interpretation, Statistical, Humans, Research Design, Confounding Factors, Epidemiologic, Survival Rate, Logistic Models, Treatment Outcome, Practice Guidelines as Topic, Propensity Score, Observational Studies as Topic
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