The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Reporting guideline for the use of Generative Artificial intelligence tools in MEdical Research: the GAMER Statement
Abstract
Objectives: Generative artificial intelligence (GAI) tools can enhance the quality and efficiency of medical research, but their improper use may result in plagiarism, academic fraud and unreliable findings. Transparent reporting of GAI use is essential, yet existing guidelines from journals and institutions are inconsistent, with no standardised principles. Design and setting: International online Delphi study. Participants: International experts in medicine and artificial intelligence. Main outcome measures: The primary outcome measure is the consensus level of the Delphi expert panel on the items of inclusion criteria for GAMER (Rreporting guideline for the use of Generative Artificial intelligence tools in MEdical Research). Results: The development process included a scoping review, two Delphi rounds and virtual meetings. 51 experts from 26 countries participated in the process (44 in the Delphi survey). The final checklist comprises nine reporting items: general declaration, GAI tool specifications, prompting techniques, tool’s role in the study, declaration of new GAI model(s) developed, artificial intelligence-assisted sections in the manuscript, content verification, data privacy and impact on conclusions. Conclusion: GAMER provides universal and standardised guideline for GAI use in medical research, ensuring transparency, integrity and quality.
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“However, the GAMER statement is limited to reporting conventions without normative guidance on which uses of LLMs are acceptable or unacceptable [14].”
From A call for clarity: a unified checklist for reporting use of large language models in writing scientific manuscripts (2026) · cites this paper as [14]
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“A meaningful limitation of any voluntary checklist is social desirability bias: authors may be reluctant to acknowledge 'generally not acceptable' uses, potentially resulting in incomplete disclosures, a concern raised by Hosseini et al. [14].”
From A call for clarity: a unified checklist for reporting use of large language models in writing scientific manuscripts (2026) · cites this paper as [14]
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“However, what remains missing is both a cross-journal consensus and guidance for authors on what constitutes acceptable versus unacceptable use of Gen AI.”
From A call for clarity: a unified checklist for reporting use of large language models in writing scientific manuscripts (2026) · cites this paper as [14]
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Collins, G. S., Moons, K. G. M., Dhiman, P., Riley, R. D., Beam, A. L., Van Calster, B., Ghassemi, M., Liu, X., Reitsma, J. B., van Smeden, M., et al. (2024) · BMJ · doi:10.1136/bmj-2023-078378 · Cited by 4,718
Ayers, J. W., Poliak, A., Dredze, M., Leas, E. C., Zhu, Z., Kelley, J. B., Faix, D. J., Goodman, A. M., Longhurst, C. A., Hogarth, M., et al. (2023) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2023.1838 · Cited by 2,613
Liu, X., Cruz Rivera, S., Moher, D., Calvert, M. J., Denniston, A. K., The SPIRIT-AI and CONSORT-AI Working Group, SPIRIT-AI and CONSORT-AI Steering Group, Chan, A.-W., Darzi, A., Holmes, C., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-1034-x · Cited by 1,421
Vasey, B., Nagendran, M., Campbell, B., Clifton, D. A., Collins, G. S., Denaxas, S., Denniston, A. K., Faes, L., Geerts, B., Ibrahim, M., et al. (2022) · Nature Medicine · doi:10.1038/s41591-022-01772-9 · Cited by 1,039
Cruz Rivera, S., Liu, X., Chan, A.-W., Denniston, A. K., Calvert, M. J., The SPIRIT-AI and CONSORT-AI Working Group, SPIRIT-AI and CONSORT-AI Steering Group, Darzi, A., Holmes, C., Yau, C., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-1037-7 · Cited by 933
The role of AI in drug discovery: challenges, opportunities, and strategies
Blanco-González, A., Cabezón, A., Seco-González, A., Conde-Torres, D., Antelo-Riveiro, P., Piñeiro, Á., & Garcia-Fandino, R. (2023) · Pharmaceuticals · doi:10.3390/ph16060891 · Cited by 690
Tools such as ChatGPT threaten transparent science; here are our ground rules for their use
(2023) · Nature · doi:10.1038/d41586-023-00191-1 · Cited by 605
Checklist for Artificial Intelligence in Medical Imaging (CLAIM): 2024 Update
Tejani, A. S., Klontzas, M. E., Gatti, A. A., Mongan, J. T., Moy, L., Park, S. H., Kahn, C. E., Panel, F. T. C. 2. U., Abbara, S., Afat, S., et al. (2024) · Radiology: Artificial Intelligence · doi:10.1148/ryai.240300 · Cited by 570 · cited 1×
“22 However, these guidelines refer either to the use of AI in general or to specific tools.”
The application of large language models in medicine: A scoping review
Meng, X., Yan, X., Zhang, K., Liu, D., Cui, X., Yang, Y., Zhang, M., Cao, C., Wang, J., Wang, X., et al. (2024) · iScience · doi:10.1016/j.isci.2024.109713 · Cited by 414
When large language models meet personalization: perspectives of challenges and opportunities
Chen, J., Liu, Z., Huang, X., Wu, C., Liu, Q., Jiang, G., Pu, Y., Lei, Y., Chen, X., Wang, X., et al. (2024) · World Wide Web · doi:10.1007/s11280-024-01276-1 · Cited by 367
Research works printed but not linked: 47
- 10.1038/s41568-024-00694-7 · DOI
- 10.1136/jme-2023-109347 · DOI
- Lin, 2024, Techniques for supercharging academic writing with generative AI, Nat Biomed Eng, 9, 426, 10.1038/s41551-024-01185-8 · DOI · Paper page
- Ordak, 2024, Using ChatGPT in Statistical Analysis: Recommendations for JACC Journals, JACC Adv, 3, 10.1016/j.jacadv.2023.100776 · DOI
- 10.1038/d41586-023-03635-w · DOI
- Anderson, 2023, AI did not write this manuscript, or did it? Can we trick the AI text detector into generated texts? The potential future of ChatGPT and AI in Sports & Exercise Medicine manuscript generation, BMJ Open Sport Exerc Med, 9, 10.1136/bmjsem-2023-001568 · DOI · Paper page
- Wu, 2024, Unveiling security, privacy, and ethical concerns of ChatGPT, Journal of Information and Intelligence, 2, 102, 10.1016/j.jiixd.2023.10.007 · DOI
- Zhou, 2024, Ethical ChatGPT: Concerns, Challenges, and Commandments, Electronics (Basel), 13, 3417
- Heyman, 2024, The impact of ChatGPT on human data collection: A case study involving typicality norming data, Behav Res Methods, 56, 4974, 10.3758/s13428-023-02235-w · DOI
- Moher, 2024, Reporting on data sharing: executive position of the EQUATOR Network, BMJ, 386, 10.1136/bmj-2024-079694 · DOI
- 10.1038/s41591-020-0941-1 · DOI · Paper page
- 10.1038/s41591-024-03425-5 · DOI · Paper page
- 10.1136/bmj.p1923 · DOI
- Moy, 2023, Guidelines for Use of Large Language Models by Authors, Reviewers, and Editors: Considerations for Imaging Journals, Radiology, 309, 10.1148/radiol.239024 · DOI
- Luo, 2023, The use of ChatGPT in medical research: do we need a reporting guideline?, Int J Surg, 109, 3750, 10.1097/JS9.0000000000000737 · DOI
- International Committee of Medical Journal Editors (ICMJE) . Recommendations for the conduct, reporting, editing and publication of scholarly work in medical journals. 2024. Available: https://www.icmje.org/recommendations
- SAGE . The distinction between Assistive AI tools and Generative AI tools, Available: https://group.sagepub.com/assistive-and-generative-ai-guidelines-for-authors
- Islam, 2024, Use of generative artificial intelligence in medical research, BMJ, 384, 10.1136/bmj.q119 · DOI
- Moher, 2010, Guidance for developers of health research reporting guidelines, PLoS Med, 7, 10.1371/journal.pmed.1000217 · DOI · Paper page
- Luo X , Tham YC , Daher M , et al . Protocol for developing the reporting guideline for the use of chatbots and other Generative Artificial intelligence tools in MEdical Research (GAMER). medRxiv [Preprint]. doi:10.1101/2024.10.15.24315506 · DOI
- 2024, Assessment of the efficacy of alkaline water in conjunction with conventional medication for the treatment of chronic gouty arthritis: A randomized controlled study: Retraction, Medicine (Baltimore), 103, 10.1097/MD.0000000000039085 · DOI
- Zhang, 2024, RETRACTED: The three-dimensional porous mesh structure of Cu-based metal-organic-framework - Aramid cellulose separator enhances the electrochemical performance of lithium metal anode batteries, Surfaces and Interfaces, 46, 104081, 10.1016/j.surfin.2024.104081 · DOI
- 10.1016/j.ijbiomac.2024.130322 · DOI
- Luo, 2024, Potential Roles of Large Language Models in the Production of Systematic Reviews and Meta-Analyses, J Med Internet Res, 26, 10.2196/56780 · DOI
- 10.1007/s11695-023-06903-w · DOI
- Kim, 2024, Assessing the Reproducibility of the Structured Abstracts Generated by ChatGPT and Bard Compared to Human-Written Abstracts in the Field of Spine Surgery: Comparative Analysis, J Med Internet Res, 26, 10.2196/52001 · DOI
- 10.1001/jamaophthalmol.2023.6917 · DOI
- 10.1038/s41386-024-01841-2 · DOI
- Lim, 2023, Benchmarking large language models’ performances for myopia care: a comparative analysis of ChatGPT-3.5, ChatGPT-4.0, and Google Bard, EBioMedicine, 95, 10.1016/j.ebiom.2023.104770 · DOI
- 10.1007/s10439-023-03272-4 · DOI · Paper page
- Meskó, 2023, Prompt Engineering as an Important Emerging Skill for Medical Professionals: Tutorial, J Med Internet Res, 25, 10.2196/50638 · DOI · Paper page
- Peng, 2024, Large-language models facilitate discovery of the molecular signatures regulating sleep and activity, Nat Commun, 15, 10.1038/s41467-024-48005-w · DOI
- 10.1093/jamia/ocae052 · DOI
- 10.1044/2023_JSLHR-23-00121 · DOI
- 10.1089/tmj.2023.0715 · DOI
- 10.1016/j.compbiomed.2023.107329 · DOI
- Pu, 2024, ChatGPT and generative AI are revolutionizing the scientific community: A Janus-faced conundrum, Imeta, 3, 10.1002/imt2.178 · DOI
- 10.1007/s11914-023-00852-0 · DOI · Paper page
- Suwała, 2024, ChatGPT-3.5 passes Poland’s medical final examination-Is it possible for ChatGPT to become a doctor in Poland?, SAGE Open Med, 12, 10.1177/20503121241257777 · DOI
- Hoppe, 2024, ChatGPT With GPT-4 Outperforms Emergency Department Physicians in Diagnostic Accuracy: Retrospective Analysis, J Med Internet Res, 26, 10.2196/56110 · DOI
- Au, 2023, Auxiliary use of ChatGPT in surgical diagnosis and treatment, Int J Surg, 109, 3940, 10.1097/JS9.0000000000000686 · DOI
- Masanneck, 2024, Triage Performance Across Large Language Models, ChatGPT, and Untrained Doctors in Emergency Medicine: Comparative Study, J Med Internet Res, 26, 10.2196/53297 · DOI
- Elsevier . The use of generative AI and AI-assisted technologies in the review process for Elsevier: Policy for book and commissioned content reviewers, 2024. Available: https://www.elsevier.com/about/policies-and-standards/the-use-of-generative-ai-and-ai-assisted-technologies-in-the-review-process [Accessed 20 Aug 2024].
- Ueda D , Walston SL , Matsumoto T , et al . Evaluating GPT-4-based ChatGPT’s clinical potential on the NEJM quiz. BMC Digit Health 2024;2. doi:10.1186/s44247-023-00058-5 · DOI
- 10.1016/j.media.2024.103230 · DOI
- 10.1038/s41591-024-03033-3 · DOI
- Collaborative, 2024, Protocol for the development of the Chatbot Assessment Reporting Tool (CHART) for clinical advice, BMJ Open, 14, 10.1136/bmjopen-2023-081155 · DOI
Cited by
Mehta, N., Felder, R. M., Kodish, E., Imrey, P. B., & Frankel, R. M. (2026) · Research Integrity and Peer Review · doi:10.1186/s41073-026-00212-3 · Cited by 9
Metadata
- Authors
- Luo, X., Tham, Y. C., Giuffrè, M., Ranisch, R., Daher, M., Lam, K., Eriksen, A. V., Hsu, C.-W., Ozaki, A., Moraes, F. Y. D., Khanna, S., Su, K.-P., Begagić, E., Bian, Z., Chen, Y., & Estill, J.
- Venue
- BMJ Evidence-Based Medicine
- Publisher
- BMJ
- Published
- 2025-05-13
- Volume
- 30
- Issue
- 6
- Pages
- 390-400
- ISSN
- 2515-446X
- 2515-4478
- PMC
- PMC12703294
- Cited by
- 97
- References
- 27
- Language
- en
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- Luo, X., Tham, Y. C., Giuffrè, M., Ranisch, R., Daher, M., Lam, K., Eriksen, A. V., Hsu, C.-W., Ozaki, A., Moraes, F. Y. D., Khanna, S., Su, K.-P., Begagić, E., Bian, Z., Chen, Y., & Estill, J. (2025). Reporting guideline for the use of Generative Artificial intelligence tools in MEdical Research: the GAMER Statement. BMJ Evidence-Based Medicine. https://doi.org/10.1136/bmjebm-2025-113825
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