Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary care in England
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Objectives: Our aims were to investigate discrepancies between depressed patients’ GlobalRating of Change (GRC) and scores on the Patient Health Questionnaire depression module (PHQ-9). Our objectives were to ascertain patients’ views on the source and meaning of mismatches and assess their clinical significance. Design: Qualitative study nested within a cohort, in a programme investigating the indications for prescribing antidepressants that will lead to a clinical benefit. Setting: Primary care practices in north-west England. Participants: We invited 32 adults with a recent diagnosis of depression and evidence of mismatch between GRC and PHQ-9 Scores to participate. Of these, 29 completed our interviews; most were women, identified as white British, had high school education or higher, were employed or retired and had been depressed for a long time. Main measures: We conducted semistructured interviews with a topic guide, focusing on experiences of depression; treatment experiences and expectations; effectiveness of the questionnaires; reasons for the mismatch; and social factors. Interviews were transcribed and subjected to interpretative phenomenological analysis. Results: We identified four themes as explanations for mismatch between GRC and PHQ-9: perceptions that GRC provided a more accurate assessment of current mental state than PHQ-9; impact of recent negative or positive life events on either measure; personal understanding of depression as normally fluctuating, and tendency to underscore on PHQ-9 as a means of self-motivation; and lack of recall. Conclusions: The combined used of the PHQ-9 and a more open question better captures the patient’s unique experiences of mental health. This approach ascertains the relevance of symptoms to the individual’s experience and influences treatment decisions. Study registration: This study was an element of NIHR Programme Grant RP-PG 0610 10048.
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The degrees of agreement and calculations of sensitivity to change in one-item analogical scales are influenced both by the interventions and by events in the patient's life between evaluations.
“Although therapist-patient agreement is also assumed to be acceptable in this measure, the degrees of agreement and the calculations of sensitivity to change are influenced both by the interventions and by events in the patient's life between evaluations (Hobbs et al., 2021; Price et al., 2022; Robinson et al., 2017).”
From Patients´ and Therapists´ Reports of Psychotherapy Outcomes: Similarities and Differences (2023) · cites this paper as Robinson et al., 2017
The Results (Negative and positive life events; page not provided) and Discussion (Summary; page not provided) link patients’ life events to mismatches between their Global Rating of Change and PHQ-9 scores. The paper does not establish that interventions affect agreement or calculations of sensitivity to change, and it compares two patient-reported measures rather than therapist and patient ratings. (LLM, conf=0.86)
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- Authors
- Robinson, J., Khan, N., Fusco, L., Malpass, A., Lewis, G., & Dowrick, C.
- Affiliations
- University of Liverpool (GB)
- University of Bristol (GB)
- University College London (GB)
- Corresponding author
- Dowrick, Christopher
- Venue
- BMJ Open
- Publisher
- BMJ
- Published
- 2017-04
- Volume
- 7
- Issue
- 4
- Pages
- e014519
- ISSN
- 2044-6055 (ISSN-L)
- PMC
- PMC5566896
- OpenAlex
- W2610232737
- Cited by
- 39
- References
- 29
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 1 · 2023: 7 · 2022: 6 · 2021: 3 · 2020: 7 · 2019: 3 · 2018: 1
- FWCI
- 3.92
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- BMJ Open (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (acceptedVersion)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- Bristol Research (University of Bristol) (submittedVersion, cc-by)
- Funders
- Programme Grants for Applied Research
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Health Professions › General Health Professions › Patient-Provider Communication in Healthcare
- Keywords
- depression, global rating of change, PHQ-9, patient-reported outcomes, patient perspectives, primary care, antidepressant prescribing, treatment expectations, life events, symptom fluctuation, self-motivation
- MeSH terms
- Patient Health Questionnaire, Adult, Antidepressive Agents, Data Interpretation, Statistical, Depression, England, Female, Humans, Male, Middle Aged, Practice Patterns, Physicians', Primary Health Care, Surveys and Questionnaires, Reproducibility of Results, Patient Satisfaction, Health Care Surveys, Qualitative Research
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