Incidence of Crohn's disease in Cardiff between 1934-1977.
Open accessAbstract
The incidence of Crohn's disease in Cardiff between 1934 and 1977 has been examined using hospital diagnostic indices and supplemented in recent years by personal records from clinicians. A total of 232 cases of Crohn's disease were confirmed after all the notes had been reviewed. There has been a large increase from 0.18/cases/10(5) of the population per year in the 1930s to 4.8 cases/10(5)/year in the 1970s. The major change in incidence is thought to be real rather than apparent and involves all forms of the disease in each age group. The recognition of Crohn's disease of the colon in recent years appears to have played a minor part in the rise in incidence.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In Cardiff, Wales, Crohn's disease incidence was low and flat in the 1930s and 1940s, spiked to 9.1 per 100,000 in 1983, and then stabilized at 6.0 per 100,000 in 1993 and 7.0 per 100,000 in 2003.
“Initially, the incidence was low and flat (0.27 and 0.09 per 100,000 in 1933 and 1943, respectively), but showed a spike towards the 1980s (0.98 per 100,000 in 1953, 2.4 per 100,000 in 1963, 5.2 per 100,000 in 1973 and 9.1 per 100,000 in 1983). Thereafter, the incidence stabilized (6.0 per 100,000 in 1993 and 7.0 per 100,000 in 2003)29–31.”
From The four epidemiological stages in the global evolution of inflammatory bowel disease (2021) · cites this paper as [30]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Crohn, B. B. (1932) · JAMA · doi:10.1001/jama.1932.02740680019005 · Cited by 1,516 · see citing works
CONTROLLED TRIAL OF SOYA-BEAN OIL IN MYOCARDIAL INFARCTION
(1968) · The Lancet · doi:10.1016/s0140-6736(68)90746-0 · Cited by 476 · see citing works
An epidemiological study of ulcerative colitis and regional enteritis in the Oxford area.
Evans, J., & Acheson, E. D. (1965) · Gut · doi:10.1136/gut.6.4.311 · Cited by 301 · see citing works
Crohn's Disease in a Defined Population
Brahme, F. J., Lindström, C., & Wenckert, A. (1975) · Gastroenterology · doi:10.1016/s0016-5085(19)32575-2 · Cited by 213 · see citing works
MYCOBACTERIA AS A POSSIBLE CAUSE OF INFLAMMATORY BOWEL DISEASE
Burnham, W. R., Lennard‐Jones, J. E., Stanford, J. L., & Bird, R. G. (1978) · The Lancet · doi:10.1016/s0140-6736(78)92699-5 · Cited by 210 · see citing works
Day, G. (1952) · The Lancet · doi:10.1016/s0140-6736(52)91316-0 · Cited by 202 · see citing works
Increased consumption of refined carbohydrates in patients with crohn's disease
Martini, G. A., & Brandes, J. W. (1976) · Journal of Molecular Medicine · doi:10.1007/bf01469792 · Cited by 200 · see citing works
AGENT TRANSMISSIBLE FROM CROHN'S DISEASE TISSUE
Mitchell, D. N., & Rees, R. J. W. (1970) · The Lancet · doi:10.1016/s0140-6736(70)92532-8 · Cited by 192 · see citing works
DISODIUM CROMOGLYCATE IN BRONCHIAL ASTHMA
Minette, A., & Eastham, R. D. (1968) · The Lancet · doi:10.1016/s0140-6736(68)90444-3 · Cited by 181 · see citing works
An Epidemiological Study of Ulcerative Colitis and Regional Enteritis Among Adults in Baltimore
Monk, M., Mendeloff, A. I., Siegel, C. I., & Lilienfeld, A. M. (1967) · Gastroenterology · doi:10.1016/s0016-5085(19)34227-1 · Cited by 160 · see citing works
An Epidemiological Study of Crohn’s Disease in Northeast Scotland
Kyle, J. (1971) · Gastroenterology · doi:10.1016/s0016-5085(19)33394-3 · Cited by 130 · see citing works
CHANGING PATTERNS IN EPIDEMIOLOGY OF CROHN'S DISEASE
Miller, D. S., Keighley, A., & Langman, M. J. S. (1974) · The Lancet · doi:10.1016/s0140-6736(74)93265-6 · Cited by 118 · see citing works
The Registrar-General's Statistical Review of England and Wales for the Year 1945
(1946) · Public Health · doi:10.1016/s0033-3506(46)80291-9 · Cited by 105 · see citing works
An Epidemiological Study of Crohn’s Disease
Norlén, B. J., Krause, U., & Bergman, L. (1970) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.1970.12096608 · Cited by 83 · see citing works
ISOLATION OF REOVIRUS-LIKE AGENTS FROM PATIENTS WITH CROHN'S DISEASE
Whorwell, P. J., Beeken, W. L., Phillips, C. A., et al. (1977) · The Lancet · doi:10.1016/s0140-6736(77)92714-3 · Cited by 81 · see citing works
Epidemiology of Ulcerative Colitis and Regional Enterocolitis (Crohn's Disease) in Norway
Myren, J., Gjone., E., Hertzberg, J., et al. (1971) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365527109181666 · Cited by 71 · see citing works
Lindquist, J. M., Plotkin, S. A., Shaw, L., et al. (1965) · BMJ · doi:10.1136/bmj.2.5475.1401 · Cited by 65 · see citing works
Breakfast and Crohn's disease.
James, A. H. (1977) · BMJ · doi:10.1136/bmj.1.6066.943 · Cited by 61 · see citing works
Clinical Features and Epidemiological Data on Crohn's Disease in the Basle Area
Fahrländer, H., & Baerlocher, C. (1971) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365527109181149 · Cited by 51 · see citing works
Epidemiological aspects of Crohn's disease in Clydesdale 1961-1970.
Smith, I., Young, S., Gillespie, G., et al. (1975) · Gut · doi:10.1136/gut.16.1.62 · Cited by 51 · see citing works
Seasonal Variations in the Clinical Presentation of Crohn's Disease and Ulcerative Colitis
Cave, D. R., & Freedman, L. S. (1975) · International Journal of Epidemiology · doi:10.1093/ije/4.4.317 · Cited by 45 · see citing works
Crohn's disease in Norway 1956-63.
Gjone., E., Orning, O. M., & Myren, J. (1966) · Gut · doi:10.1136/gut.7.4.372 · Cited by 43 · see citing works
Breakfast and dietary aspects of Crohn's disease.
Mayberry, J. F., Rhodes, J., & Newcombe, R. G. (1978) · BMJ · doi:10.1136/bmj.2.6149.1401 · Cited by 42 · see citing works
Self-citationAn Epidemiological Study of Regional Enteritis and Acute Ileitis in Copenhagen County
Høj, L., Jensen, P. B., Bonnevie, O., et al. (1973) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.1973.12096723 · Cited by 33 · see citing works
Crohn’s disease in northern Ireland — A retrospective survey of 159 cases
Humphreys, W. G., & Parks, T. G. (1975) · Irish Journal of Medical Science (1971 -) · doi:10.1007/bf02939051 · Cited by 19 · see citing works
THE MEDICAL PROFESSION AND THE MERCANTILE MARINE
Jones, H. J. R. (1903) · BMJ · doi:10.1136/bmj.1.2207.943-b · Cited by 19 · see citing works
An epidemiological study of regional enteritis in the gloucester area
Tresadern, J. C., Gear, M. W. L., & Nicol, A. (1973) · British journal of surgery · doi:10.1002/bjs.1800600513 · Cited by 18 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Registrar-General's Statistical Review of England and Wales 1950-1975. Her Majesty's Stationery Office, London.
Cited by
Sorted by citations
Molodecky, N. A., Soon, I. S., Rabi, D. M., Ghali, W. A., Ferris, M., Chernoff, G., Benchimol, E. I., Panaccione, R., Ghosh, S., Barkema, H. W., et al. (2012) · Gastroenterology · doi:10.1053/j.gastro.2011.10.001 · Cited by 4,833 · see citing works
The four epidemiological stages in the global evolution of inflammatory bowel disease
Kaplan, G. G., & Windsor, J. W. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-00360-x · Cited by 1,351 · see citing works
Kaplan, G. G., & Ng, S. C. (2016) · The Lancet Gastroenterology & Hepatology · doi:10.1016/s2468-1253(16)30077-2 · Cited by 240 · see citing works
Cardiff Crohn's disease jubilee: the incidence over 50 years.
Rose, J. D., Roberts, G. M., Williams, G., Mayberry, J. F., & Rhodes, J. (1988) · Gut · doi:10.1136/gut.29.3.346 · Cited by 136 · see citing works
Self-citationRoberts, S. E., Thorne, K., Thapar, N., Broekaert, I., Benninga, M. A., Dolinsek, J., Mas, E., Miele, E., Orel, R., Pienar, C., et al. (2020) · Journal of Crohn's and Colitis · doi:10.1093/ecco-jcc/jjaa037 · Cited by 116 · see citing works
The incidence of Crohn’s disease in Cardiff over the last 75 years: an update for 1996–2005
GUNESH, S., THOMAS, G. A. O., WILLIAMS, G. T., ROBERTS, A., & HAWTHORNE, A. B. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2007.03576.x · Cited by 89 · see citing works
- Authors
- Mayberry, J., Rhodes, J., & Hughes, L. E.
- ORCID
- Mayberry, J
- Venue
- Gut
- Publisher
- BMJ
- Published
- 1979-07-01
- Volume
- 20
- Issue
- 7
- Pages
- 602-608
- ISSN
- 0017-5749 (ISSN-L)
- PMC
- PMC1412523
- OpenAlex
- W2085558339
- Cited by
- 95
- References
- 27
- Citations by year
- 2026: 1 · 2022: 1 · 2020: 2 · 2017: 1 · 2016: 2 · 2014: 1 · 2012: 3
- FWCI
- 7.58
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gut (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
- Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
- Health Sciences › Medicine › Surgery › Gastrointestinal disorders and treatments
- Keywords
- Crohn's disease, incidence trends, Cardiff, case ascertainment, Crohn's colitis, age groups, temporal trends
- MeSH terms
- Adolescent, Adult, Age Factors, Aged, Child, Crohn Disease, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Time Factors, Wales
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
