The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Increase in gamma/delta T cell receptor bearing lymphocytes in normal small bowel mucosa in latent coeliac disease.
Open accessAbstract
A jejunal biopsy specimen from an asymptomatic 35 year old man was studied because of a low serum titre of reticulin antibody and the finding of coeliac disease in his son. In this specimen villous structure was quite normal as was the total number of intraepithelial lymphocytes, but the number of gamma/delta T cell receptor bearing lymphocytes was 10 times higher than the mean in control subjects. Two years later a further biopsy specimen was obtained because of clinical symptoms and an increased titre of reticulin antibody. This specimen showed villous atrophy with crypt hyperplasia and increased infiltration of intraepithelial lymphocytes compatible with coeliac disease. A control biopsy specimen taken during gluten free diet showed normalisation of the villous architecture. Latent coeliac disease may be characterised by an increase in gamma/delta positive cells similar to that seen in established coeliac disease.
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Citations
Cites
Intraepithelial T Cells of the TcRγ/δ+CD8− and Vδ1/Jδ1+ Phenotypes are Increased in Coeliac Disease
HALSTENSEN, T. S., SCOTT, H., & BRANDTZAEG, P. (1989) · Scandinavian Journal of Immunology · doi:10.1111/j.1365-3083.1989.tb02474.x · Cited by 311
Cited by
The Oslo definitions for coeliac disease and related terms
Ludvigsson, J. F., Leffler, D. A., Bai, J. C., Biagi, F., Fasano, A., Green, P. H. R., Hadjivassiliou, M., Kaukinen, K., Kelly, C. P., Leonard, J. N., et al. (2013) · Gut · doi:10.1136/gutjnl-2011-301346 · Cited by 1,721
Clinical and pathological spectrum of coeliac disease--active, silent, latent, potential.
Ferguson, A., Arranz, E., & O'Mahony, S. (1993) · Gut · doi:10.1136/gut.34.2.150 · Cited by 395
The widening spectrum of celiac disease
Murray, J. A. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.3.354 · Cited by 313
Histopathology of celiac disease
Oberhuber, G. (2000) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(01)80003-2 · Cited by 288
Celiac disease–like abnormalities in a subgroup of patients with irritable bowel syndrome
Wahnschaffe, U., Ullrich, R., Riecken, E. O., & Schulzke, J. D. (2001) · Gastroenterology · doi:10.1053/gast.2001.29572 · Cited by 280
Metadata
- Authors
- Mäki, M., Holm, K., Collin, P., & Savilahti, E.
- Venue
- Gut
- Publisher
- BMJ
- Published
- 1991-11
- Volume
- 32
- Issue
- 11
- Pages
- 1412-1414
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- OpenAlex
- W2110155360
- Cited by
- 177
- References
- 1
- FWCI
- 7.87
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Mäki, M., Holm, K., Collin, P., & Savilahti, E. (1991). Increase in gamma/delta T cell receptor bearing lymphocytes in normal small bowel mucosa in latent coeliac disease. Gut. https://doi.org/10.1136/gut.32.11.1412
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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