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Role of myocardial perfusion imaging for risk stratification in suspected or known coronary artery disease
Open accessAbstract
Nuclear cardiology is an evolving specialty that has recently benefited from technological and radiopharmaceutical advances. As a result there has been an increase in the accuracy of myocardial perfusion imaging (MPI) with gated single photon emission computed tomography (SPECT) for assessing the diagnosis and prognosis of coronary artery disease. Moreover, ECG gated SPECT allows the simultaneous assessment of both myocardial perfusion and left ventricular function, which provides additional prognostic value. With increasing concern over early detection of coronary artery disease and its effective treatment, myocardial perfusion imaging is ideally placed to provide a full “one stop” functional assessment for any patient, irrespective of their exercise capacity. This applies not only to patients with chest pain but also to those with myocardial infarction, revascularisation, and heart failure, and those being assessed for non-cardiac surgery. The focus of this review is the use of myocardial perfusion imaging in risk stratification for coronary artery disease.
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“In cardiology, it enables the assessment of myocardial perfusion and viability, aiding in the management of coronary artery disease [49].”
From Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation (2024) · cites this paper as [49]
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Metadata
- Authors
- Sabharwal, N. K., & Lahiri, A.
- Affiliations
- Northwick Park Hospital (GB)
- Corresponding author
- Lahiri, A
- ORCID
- Sabharwal, N K
- Venue
- Heart
- Publisher
- BMJ
- Published
- 2003-10-31
- Volume
- 89
- Issue
- 11
- Pages
- 1291-1297
- ISSN
- 1355-6037 (ISSN-L)
- 1468-201X
- PMC
- PMC1767933
- OpenAlex
- W2115529930
- Cited by
- 72
- References
- 62
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 1 · 2022: 4 · 2021: 7 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 3 · 2016: 4 · 2015: 1 · 2014: 3 · 2013: 2 · 2012: 4
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Heart (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Medical Imaging Techniques and Applications
- Keywords
- myocardial perfusion imaging, risk stratification, coronary artery disease, gated SPECT, left ventricular function, prognosis, myocardial infarction, heart failure, non-cardiac surgery, chest pain
- MeSH terms
- Coronary Artery Disease, Electrocardiography, Female, Humans, Middle Aged, Tomography, Emission-Computed, Single-Photon, Technetium Tc 99m Sestamibi, Risk Assessment, Radiopharmaceuticals, Echocardiography, Stress
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