The DOI matches its Crossref record; 61 of the 62 references it cites were found in a registry or an index.
Role of myocardial perfusion imaging for risk stratification in suspected or known coronary artery disease
Open accessAbstract
Nuclear cardiology is an evolving specialty that has recently benefited from technological and radiopharmaceutical advances. As a result there has been an increase in the accuracy of myocardial perfusion imaging (MPI) with gated single photon emission computed tomography (SPECT) for assessing the diagnosis and prognosis of coronary artery disease. Moreover, ECG gated SPECT allows the simultaneous assessment of both myocardial perfusion and left ventricular function, which provides additional prognostic value. With increasing concern over early detection of coronary artery disease and its effective treatment, myocardial perfusion imaging is ideally placed to provide a full “one stop” functional assessment for any patient, irrespective of their exercise capacity. This applies not only to patients with chest pain but also to those with myocardial infarction, revascularisation, and heart failure, and those being assessed for non-cardiac surgery. The focus of this review is the use of myocardial perfusion imaging in risk stratification for coronary artery disease.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In cardiology, it enables the assessment of myocardial perfusion and viability, aiding in the management of coronary artery disease [49].”
From Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation (2024) · cites this paper as [49]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
American Heart Association Writing Group on Myocardial Segmentation and Registration for Cardiac Imaging:, Cerqueira, M. D., Weissman, N. J., Dilsizian, V., Jacobs, A. K., Kaul, S., Laskey, W. K., Pennell, D. J., Rumberger, J. A., Ryan, T., et al. (2002) · Circulation · doi:10.1161/hc0402.102975 · Cited by 6,990
Analysis of probability as an aid in the clinical diagnosis of coronary artery disease.
Diamond, G. A., & Forrester, J. S. (1979) · New England Journal of Medicine · doi:10.1056/nejm197906143002402 · Cited by 2,664
Automatic quantification of ejection fraction from gated myocardial perfusion SPECT.
Germano, G., Kiat, H., Kavanagh, P., Moriel, M., Mazzanti, M., Su, H.-T., Train, K. F. V., & Berman, D. S. (1995) · PubMed · Cited by 1,239
Hachamovitch, R., Berman, D. S., Shaw, L. J., Kiat, H., Cohen, I., Cabico, J. A., Friedman, J., & Diamond, G. A. (1998) · Circulation · doi:10.1161/01.cir.97.6.535 · Cited by 1,221
Prognostic Value of a Treadmill Exercise Score in Outpatients with Suspected Coronary Artery Disease
Mark, D. B., Shaw, L., Harrell, F. E., Hlatky, M. A., Lee, K. L., Bengtson, J. R., McCants, C. B., Califf, R. M., & Pryor, D. B. (1991) · New England Journal of Medicine · doi:10.1056/nejm199109193251204 · Cited by 837
Hachamovitch, R., Berman, D. S., Kiat, H., Cohen, I., Cabico, J. A., Friedman, J., & Diamond, G. A. (1996) · Circulation · doi:10.1161/01.cir.93.5.905 · Cited by 836
Results of coronary artery surgery in patients with poor left ventricular function (CASS).
Alderman, E. L., Fisher, L. D., Litwin, P., Kaiser, G. C., Myers, W. O., Maynard, C., Levine, F., & Schloss, M. (1983) · Circulation · doi:10.1161/01.cir.68.4.785 · Cited by 804
Cerqueira, M. D., Weissman, N. J., Dilsizian, V., Jacobs, A. K., Kaul, S., Laskey, W. K., Pennell, D. J., Rumberger, J. A., Ryan, T., & Verani, M. S. (2002) · Journal of Nuclear Cardiology · doi:10.1067/mnc.2002.123122 · Cited by 770
Sharir, T., Germano, G., Kavanagh, P. B., Lai, S., Cohen, I., Lewin, H. C., Friedman, J. D., Zellweger, M. J., & Berman, D. S. (1999) · Circulation · doi:10.1161/01.cir.100.10.1035 · Cited by 582
Risk assessment using single-photon emission computed tomographic technetium-99m sestamibi imaging
Iskander, S., & Iskandrian, A. E. (1998) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(98)00177-6 · Cited by 475
Taillefer, R., DePuey, E. G., Udelson, J. E., Beller, G. A., Latour, Y., & Reeves, F. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(96)00435-4 · Cited by 425
Pagley, P. R., Beller, G. A., Watson, D. D., Gimple, L. W., & Ragosta, M. (1997) · Circulation · doi:10.1161/01.cir.96.3.793 · Cited by 392
Cerqueira, M. D., Weissman, N. J., Dilsizian, V., Jacobs, A. K., Kaul, S., Laskey, W. K., Pennell, D. J., Rumberger, J. A., Ryan, T., & Verani, M. S. (2002) · Journal of the American Society of Echocardiography · doi:10.1067/mje.2002.123374 · Cited by 392
Prognostic value of thallium-201 myocardial perfusion imaging. A diagnostic tool comes of age.
Brown, K. A. (1991) · Circulation · doi:10.1161/01.cir.83.2.363 · Cited by 390
Estimating the likelihood of significant coronary artery disease
Pryor, D. B., Harrell, F. E., Lee, K. L., Califf, R. M., & Rosati, R. A. (1983) · The American Journal of Medicine · doi:10.1016/0002-9343(83)90406-0 · Cited by 353
Shaw, L. J., Hachamovitch, R., Berman, D. S., Marwick, T. H., Lauer, M. S., Heller, G. V., Iskandrian, A. E., Kesler, K. L., Travin, M. I., Lewin, H. C., et al. (1999) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(98)00606-8 · Cited by 353
Johnson, L. L., Verdesca, S. A., Aude, W. Y., Xavier, R. C., Nott, L. T., Campanella, M. W., & Germano, G. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00388-4 · Cited by 313
Left ventricular function and perfusion from gated SPECT perfusion images: an integrated method.
Faber, T. L., Cooke, C. D., Folks, R. D., Vansant, J., Nichols, K. J., DePuey, E. G., Pettigrew, R. I., & Garcia, E. V. (1999) · PubMed · Cited by 256
Value of Gating of Technetium-99m Sestamibi Single-Photon Emission Computed Tomographic Imaging
Smanio, P. E. P., Watson, D. D., Segalla, D. L., Vinson, E. L., Smith, W. H., & Beller, G. A. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00363-x · Cited by 252
Marzullo, P., Parodi, O., Reisenhofer, B., Sambuceti, G., Picano, E., Distante, A., Gimelli, A., & L’Abbate, A. (1993) · The American Journal of Cardiology · doi:10.1016/0002-9149(93)90733-s · Cited by 233
Marwick, T. H., Case, C. C., Vasey, C. G., Allen, S., Short, L., & Thomas, J. D. (2001) · Circulation · doi:10.1161/01.cir.103.21.2566 · Cited by 215
Senior, R., Kaul, S., & Lahiri, A. (1999) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(99)00102-3 · Cited by 213
Self-citationPrediction of mortality using dobutamine echocardiography
Marwick, T. H., Case, C. C., Sawada, S. G., Rimmerman, C. M., Brenneman, P., Kovacs, R., Short, L., & Lauer, M. S. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)01191-8 · Cited by 194
The diagnostic accuracy of the exercise electrocardiogram: A meta-analysis of 22 years of research
Detrano, R., Gianrossi, R., & Froelicher, V. F. (1989) · Progress in Cardiovascular Diseases · doi:10.1016/0033-0620(89)90025-x · Cited by 193
Vanzetto, G., Ormezzano, O., Fagret, D., Comet, M., Denis, B., & Machecourt, J. (1999) · Circulation · doi:10.1161/01.cir.100.14.1521 · Cited by 187
Economics of Myocardial Perfusion Imaging in Europe—the EMPIRE study
Underwood, S. R. (1999) · European Heart Journal · doi:10.1053/euhj.1998.1196 · Cited by 180
Myocardial Perfusion Imaging With 99m Tc Tetrofosmin
Zaret, B. L., Rigo, P., Wackers, F. J. T., Hendel, R. C., Braat, S. H. J. G., Iskandrian, A. S., Sridhara, B. S., Jain, D., Itti, R., Serafini, A. N., et al. (1995) · Circulation · doi:10.1161/01.cir.91.2.313 · Cited by 175
Self-citationGibbons, R. J., Hodge, D. O., Berman, D. S., Akinboboye, O. O., Heo, J., Hachamovitch, R., Bailey, K. R., & Iskandrian, A. E. (1999) · Circulation · doi:10.1161/01.cir.100.21.2140 · Cited by 161
Stratmann, H. G., Williams, G. A., Wittry, M. D., CHAITMAN, B. R., & Miller, D. D. (1994) · Circulation · doi:10.1161/01.cir.89.2.615 · Cited by 148
Positron emission tomography detects evidence of viability in rest technetium-99m sestamibi defects
Sawada, S. G., Allman, K. C., Muzik, O., Beanlands, R. S., Wolfe, E. R., Gross, M. D., Fig, L. M., & Schwaiger, M. (1994) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)90506-1 · Cited by 141
Hachamovitch, R., Berman, D. S., Kiat, H., Cohen, I., Lewin, H. C., Amanullah, A. M., Kang, X., Friedman, J. D., & Diamond, G. A. (1997) · The American Journal of Cardiology · doi:10.1016/s0002-9149(97)00390-1 · Cited by 135
Wackers, F. J. T., Russo, D. J., Russo, D., & Clements, J. P. (1985) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(85)80247-3 · Cited by 132
Adenosine combined with dynamic exercise for myocardial perfusion imaging
Pennell, D. J., Mavrogeni, S. I., Forbat, S. M., Karwatowski, S. P., & Underwood, S. R. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(95)00011-r · Cited by 125
Stress-Induced Reversible and Mild-to-Moderate Irreversible Thallium Defects
Kitsiou, A. N., Srinivasan, G., Quyyumi, A. A., Summers, R. M., Bacharach, S. L., & Dilsizian, V. (1998) · Circulation · doi:10.1161/01.cir.98.6.501 · Cited by 123
Chouraqui, P., Rodrigues, E. A., Berman, D. S., & Maddahi, J. (1990) · The American Journal of Cardiology · doi:10.1016/0002-9149(90)91131-o · Cited by 107
Siebelink, H. J., Blanksma, P. K., Crijns, H. J. G. M., Bax, J. J., Boven, A. J. V., Kingma, T., Piers, D. A., Pruim, J., Jager, P. L., Vaalburg, W., et al. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)01087-1 · Cited by 106
Heller, G. V., Herman, S. D., Travin, M. I., Baron, J. I., Santos-Ocampo, C. D., & McClellan, J. R. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(95)00329-0 · Cited by 105
Sridhara, B. S., Braat, S. H. J. G., Rigo, P., Itti, R., Cload, P., Lahiri, A., Raval, T. A. O. U., & Foulon, J. (1993) · The American Journal of Cardiology · doi:10.1016/0002-9149(93)90855-7 · Cited by 101
Self-citationPrognostic value of normal technetium-99m-sestamibi cardiac imaging.
Brown, K. A., Altland, E., & Rowen, M. (1994) · PubMed · Cited by 91
Stratmann, H. G., Tamesis, B. R., Younis, L. T., Wittry, M. D., & Miller, D. D. (1994) · The American Journal of Cardiology · doi:10.1016/0002-9149(94)90927-x · Cited by 86
Prognostic Implications of Normal Exercise Thallium 201 Images
Wahl, J. M. (1985) · Archives of Internal Medicine · doi:10.1001/archinte.1985.00360020073014 · Cited by 78
Senior, R., Kaul, S., Raval, U., & Lahiri, A. (2002) · Journal of Nuclear Cardiology · doi:10.1067/mnc.2002.123913 · Cited by 78
Self-citationSoman, P., Taillefer, R., DePuey, E. G., Udelson, J. E., & Lahiri, A. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)01148-7 · Cited by 65
Self-citationThe prognostic value of a normal Tc-99m sestamibi SPECT study in suspected coronary artery disease
Soman, P., Parsons, A., Lahiri, N., & Lahiri, A. (1999) · Journal of Nuclear Cardiology · doi:10.1016/s1071-3581(99)90036-3 · Cited by 55
Self-citationGlover, D. K., Ruiz, M., Yang, J. Y., Koplan, B. A., Allen, T. R., Smith, W. H., Watson, D. D., Barrett, R. J., & Beller, G. (1996) · Circulation · doi:10.1161/01.cir.94.7.1726 · Cited by 54
Raiker, K., Sinusas, A. J., Wackers, F. J. T., & Zaret, B. L. (1994) · Journal of Nuclear Cardiology · doi:10.1007/bf02961599 · Cited by 52
Sansoy, V., Glover, D. K., Watson, D. D., Ruiz, M., Smith, W. H., Simanis, J. P., & Beller, G. (1995) · Circulation · doi:10.1161/01.cir.92.4.994 · Cited by 50
Nichols, K. J., Santana, C. A., Folks, R. D., Krawczynska, E. G., Cooke, C. D., Faber, T. L., Bergmann, S. R., & Garcia, E. V. (2002) · Journal of Nuclear Cardiology · doi:10.1067/mnc.2002.121449 · Cited by 49
Berman, D. S., Kiat, H., Train, K. F. V., Friedman, J. D., Garcia, E. V., & Maddahi, J. (1990) · The American Journal of Cardiology · doi:10.1016/0002-9149(90)90616-9 · Cited by 47
Groutars, R. G. E. J., Verzijlbergen, J. F., Muller, A. J., Ascoop, C. A. P. L., Buul, M. M. C. T.-V., Zwinderman, A. H., van Hemel, N. M., & van der Wall, E. E. (2000) · Journal of Nuclear Cardiology · doi:10.1067/mnc.2000.105634 · Cited by 47
Risk Stratification in Coronary Artery Disease: Implications for Stabilization and Prevention
Berman, D. S., Hachamovitch, R., Lewin, H. C., Friedman, J. D., Shaw, L. J., & Germano, G. (1997) · The American Journal of Cardiology · doi:10.1016/s0002-9149(97)00380-9 · Cited by 47
Steinberg, E. H., Koss, J. H., Lee, M. S., Grunwald, A. M., & Bodenheimer, M. (1993) · The American Journal of Cardiology · doi:10.1016/0002-9149(93)90538-n · Cited by 43
Borges‐Neto, S., Javaid, A., Shaw, L. K., Kong, D. F., Hanson, M. W., Pagnanelli, R., RAVIZZINI, G. C., & Coleman, R. E. (2000) · Radiology · doi:10.1148/radiology.215.2.r00ma13529 · Cited by 40
Assessment of myocardial viability.
Beller, G. (1997) · PubMed · Cited by 26
Assessment of myocardial viability
Beller, G. (1997) · Current Opinion in Cardiology · doi:10.1097/00001573-199712050-00005 · Cited by 19
Swinburn, J., Stubbs, P. J., Soman, P., Collinson, P. O., Raval, U., Senior, R., & Lahiri, A. (2002) · Journal of Nuclear Cardiology · doi:10.1067/mnc.2002.125216 · Cited by 16
Self-citationPrediction of mortality using dobutamine echocardiography
Marwick, T. H., Case, C., & Sawada, S. (2001) · ACC Current Journal Review · doi:10.1016/s1062-1458(01)00306-3 · Cited by 16
Evaluation of exercise-induced stunning using myocardial perfusion imaging.
Otto, A. C., van Staden, J., van Aardt, A., van Aswegen, E., Joubert, G., & Englebrecht, H. (2001) · PubMed · Cited by 9
Khattar, R. S., Senior, R., Joseph, D., & Lahiri, A. (1997) · Journal of Nuclear Cardiology · doi:10.1016/s1071-3581(97)90081-7 · Cited by 6
Self-citationThe role of cardiac imaging in optimizing therapy in heart failure
Lahiri, A. (2000) · Journal of Nuclear Cardiology · doi:10.1067/mnc.2000.104276 · Cited by 2
Self-citation8. Evaluation of exercise induced stunning using myocardial perfusion imaging
Otto, A., Staden, J. V., Aardt, P. A. V., van Aswegen, E., Joubert, G., Engelbrecht, G., & Snyman, U. (2002) · Nuclear Medicine Communications · doi:10.1097/00006231-200212000-00019 · Cited by 2
Research works printed but not linked: 6
- 1995, J Nucl Med, 36, 2138
- 1999, J Nucl Med, 40, 650
- 1997, Am J Cardiol, 79, 10
- 2001, Cardiovasc J Southern Africa, 12, 259
- 2002, J Am Coll Cardiol, 39, 172A
- 1994, J Nucl Med, 35, 554
Cited by
Gerber, B. L., Raman, S. V., Nayak, K. S., Epstein, F. H., Ferreira, P., Axel, L., & Kraitchman, D. L. (2008) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/1532-429x-10-18 · Cited by 217
Giannakoulas, G. A., Dimopoulos, K., Engel, R., Göktekín, Ö., Küçükdurmaz, Z., Vatankulu, M. A., Bédard, É., Diller, G., Papaphylactou, M., Francis, D. P., et al. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.01.353 · Cited by 178
Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation
Dhoundiyal, S., Srivastava, S., Kumar, S., Singh, G., Ashique, S., Pal, R., Mishra, N., & Taghizadeh-Hesary, F. (2024) · European Journal of Medical Research · doi:10.1186/s40001-023-01627-0 · Cited by 144
“In cardiology, it enables the assessment of myocardial perfusion and viability, aiding in the management of coronary artery disease [49].”
BackgroundNikolaou, K., Sanz, J., Poon, M., Wintersperger, B. J., Ohnesorge, B. M., Rius, T., Fayad, Z. A., Reiser, M. F., & Becker, C. R. (2005) · European Radiology · doi:10.1007/s00330-005-2672-6 · Cited by 141
Ramon, A. J., Yang, Y., Pretorius, P. H., Johnson, K. L., King, M. A., & Wernick, M. N. (2020) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2020.2979940 · Cited by 98
Metadata
- Authors
- Sabharwal, N. K., & Lahiri, A.
- Affiliations
- Northwick Park Hospital (GB)
- Corresponding author
- Lahiri, A
- ORCID
- Sabharwal, N K
- Venue
- Heart
- Publisher
- BMJ
- Published
- 2003-10-31
- Volume
- 89
- Issue
- 11
- Pages
- 1291-1297
- ISSN
- 1355-6037 (ISSN-L)
- 1468-201X
- PMC
- PMC1767933
- OpenAlex
- W2115529930
- Cited by
- 72
- References
- 62
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 1 · 2022: 4 · 2021: 7 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 3 · 2016: 4 · 2015: 1 · 2014: 3 · 2013: 2 · 2012: 4
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Heart (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Medical Imaging Techniques and Applications
- Keywords
- myocardial perfusion imaging, risk stratification, coronary artery disease, gated SPECT, left ventricular function, prognosis, myocardial infarction, heart failure, non-cardiac surgery, chest pain
- MeSH terms
- Coronary Artery Disease, Electrocardiography, Female, Humans, Middle Aged, Tomography, Emission-Computed, Single-Photon, Technetium Tc 99m Sestamibi, Risk Assessment, Radiopharmaceuticals, Echocardiography, Stress
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.