CoChat
Sign Up
Cited by 72Pituitary Gland Disorders and TreatmentsTraumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Analysis of abnormalities in pituitary gland in non-missile head injury: study of 100 consecutive cases

Open access
Harper, C G, Doyle, D, Adams, J H, Graham, D I·1986·Journal of Clinical Pathology
DOI 10.1136/jcp.39.7.769PMC PMC500044
Open this paper in CoChat — free accountOpen PDF

Abstract

Pituitary glands, obtained at necropsy from a consecutive series of 100 patients who had died as a result of non-missile head injuries, were examined to define the incidence and pathogenesis of abnormality.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1136/jcp.39.7.769

Cites

29 of 29 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Autopsy results have revealed damage to the pituitary capsule (most common form, 23-59% of cases), pituitary stalk, and anterior and posterior lobes in forms of hemorrhage, necrosis, and fibrosis.

    “Autopsy results have revealed different types of lesions including damage to the pituitary capsule (most common form of pituitary injury after TBI, observed in 23-59% of cases), to the pituitary stalk, and to the anterior and posterior lobes in the forms of hemorrhage, necrosis, and fibrosis (139 -144).”

    From Pituitary Dysfunction After Traumatic Brain Injury: A Clinical and Pathophysiological Approach (2015) · cites this paper as [141]

    The Haemorrhage and Infarction sections report lesions of the pituitary stalk and both lobes; the Anterior Lobe section describes necrosis followed by a fibrous scar. But the paper does not report capsule damage in 23–59% of cases. Its Discussion instead identifies anterior-lobe infarction as the most common important abnormality. Page numbers were not available in our copy. (LLM, conf=0.88)

    Experimental — accuracy not yet measured

  • In Harper et al.'s investigation, all patients with large- or medium-sized pituitary infarctions had increased ICP at some point.

    “In this investigation, all patients with large-or medium-sized pituitary infarctions had increased ICP at some point.”

    From Pituitary Dysfunction After Traumatic Brain Injury: A Clinical and Pathophysiological Approach (2015) · cites this paper as [141]

  • Interruption of the hypothalamo-hypophyseal portal blood supply was assumed to be one of the possible mechanisms of anterior lobe infarction.

    “Interruption of the hypothalamo-hypophyseal portal blood supply (ie, due to ICP or direct vascular insult) was assumed to be one of the possible mechanisms of anterior lobe infarction (18, 132, 135, 141, 142).”

    From Pituitary Dysfunction After Traumatic Brain Injury: A Clinical and Pathophysiological Approach (2015) · cites this paper as [141]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

2 of the 31 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

  1. [11]11. "Adams JH, Daniel PM, Pritchard MML, Venables PH. A method for measuring the volume of the pituitary gland. J Physiol 1963;166:37-9.
  2. [18]18. Adams H, Graham DI. In: Brock M, Dietz H, eds. Intracranial pressure. Berlin: Springer 1972:250-3.
  3. [23]23. 23Taylor WH. Hypernatremia in cerebral disorders. J Clin Pathol 1962;15:21 1-9.
  4. [28]28. Kramer W. Extensive necrosis of the brain developing during reanimation. Proceedings of the fifth international congress of neuropathology. Excerpta Medica 1966;100:33.

Cited by

Sorted by citations

Related

Authors
Harper, C. G., Doyle, D., Adams, J. H., & Graham, D. I.
Affiliations
  • The University of Sydney (AU)
  • Southern General Hospital (GB)
ORCID
Graham, D I
Venue
Journal of Clinical Pathology
Publisher
BMJ
Published
1986-07
Volume
39
Issue
7
Pages
769-773
ISSN
  • 0021-9746 (ISSN-L)
  • 1472-4146
DOI
10.1136/jcp.39.7.769
PMC
PMC500044
OpenAlex
W2143468403
Cited by
72
References
31
Citations by year
2026: 3 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 8 · 2018: 3 · 2017: 1 · 2016: 4 · 2015: 4 · 2014: 1 · 2013: 4 · 2012: 6
FWCI
0.65
Type
journal article
Language
en
Open access
Locations
  • Journal of Clinical Pathology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
  • Health Sciences › Medicine › Neurology › Traumatic Brain Injury and Neurovascular Disturbances
  • Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
Keywords
traumatic brain injury, pituitary pathology, incidence, pathogenesis, autopsy findings
MeSH terms
Adolescent, Adult, Aged, Child, Child, Preschool, Female, Craniocerebral Trauma, Hemorrhage, Humans, Infant, Infarction, Male, Middle Aged, Pituitary Gland, Pituitary Gland, Anterior, Pituitary Gland, Posterior

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review