The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Using natural experiments to evaluate population health interventions: new Medical Research Council guidance
Open accessAbstract
Natural experimental studies are often recommended as a way of understanding the health impact of policies and other large scale interventions. Although they have certain advantages over planned experiments, and may be the only option when it is impossible to manipulate exposure to the intervention, natural experimental studies are more susceptible to bias. This paper introduces new guidance from the Medical Research Council to help researchers and users, funders and publishers of research evidence make the best use of natural experimental approaches to evaluating population health interventions. The guidance emphasises that natural experiments can provide convincing evidence of impact even when effects are small or take time to appear. However, a good understanding is needed of the process determining exposure to the intervention, and careful choice and combination of methods, testing of assumptions and transparent reporting is vital. More could be learnt from natural experiments in future as experience of promising but lesser used methods accumulates.
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“health if an intervention has other known benefits, if it has been shown to be effective in other settings, or if its main purpose is to achieve non-health outcomes.(14) Even if such ethical and practical restrictions are absent, an RCT may still be politically unwelcome.”
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Process evaluation of complex interventions: Medical Research Council guidance
Moore, G. F., Audrey, S., Barker, M., Bond, L., Bonell, C., Hardeman, W., Moore, L., O'Cathain, A., Tinati, T., Wight, D., et al. (2015) · BMJ · doi:10.1136/bmj.h1258 · Cited by 6,204
Skivington, K., Matthews, L., Simpson, S. A., Craig, P., Baird, J., Blazeby, J. M., Boyd, K. A., Craig, N., French, D. P., McIntosh, E., et al. (2021) · BMJ · doi:10.1136/bmj.n2061 · Cited by 5,808
Self-citationThe need for a complex systems model of evidence for public health
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Self-citationNature Contact and Human Health: A Research Agenda
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“The more thorny challenge is conceptual: natural experiments are highly susceptible to bias, that is to say, to the tendency for exposure to vary across a study population by factors that are also associated with outcomes (Craig et al. 2012; Rutter 2007).”
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Metadata
- Authors
- Craig, P., Cooper, C., Gunnell, D., Haw, S., Lawson, K., Macintyre, S., Ogilvie, D., Petticrew, M., Reeves, B., Sutton, M., & Thompson, S.
- Venue
- Journal of Epidemiology and Community Health
- Publisher
- BMJ
- Published
- 2012-05-10
- Volume
- 66
- Issue
- 12
- Pages
- 1182-1186
- ISSN
- 0141-7681 (ISSN-L)
- 0143-005X
- 1470-2738
- OpenAlex
- W2110904269
- Cited by
- 912
- References
- 11
- FWCI
- 41.65
- Type
- journal article
- Language
- en
- Open access
- bronze
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