Neurolinguistic analysis of the language abilities of a patient with a "double disconnection syndrome": a case of subangular alexia in the presence of mixed transcortical aphasia.
Open accessAbstract
In contrast to the classic form of alexia without agraphia, subangular alexia results from a single lesion located deep in the white matter of the left parietal lobe. In the present report, a patient with subangular alexia and features of mixed transcortical aphasia is described. Neurolinguistic findings include: alexia without agraphia, paucity of spontaneous speech, moderate auditory comprehension difficulty, excellent repetition, echopraxia, colour agnosia, and naming disorder. Neurolinguistic tests revealed intact phonological organisation and grammatical filter." Our studies revealed a "double disconnection syndrome," the co-existence of two relatively rare neurobehavioural disorders. Furthermore, the studies reported here clearly show dissociations of language functions in both the visual and auditory modality, which demonstrates that the stages of language processing are separable.
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Output projections from the VWFA to lateral language areas may be interrupted in parietal white matter, providing a plausible account for subangular alexia.
“Conversely, output projections from the VWFA to lateral language areas may be interrupted during their course in the parietal white matter, providing a plausible account for the so-called subangular alexia (Greenblatt, 1976; Iragui and Kritchevsky, 1991; Pirozzolo et al., 1981).”
From Specialization within the ventral stream: the case for the visual word form area (2004) · cites this paper as Pirozzolo et al., 1981
Cites
DISCONNEXION SYNDROMES IN ANIMALS AND MAN
Geschwind, N. (1965) · Brain · doi:10.1093/brain/88.2.237 · Cited by 3,419 · see citing works
(1977) · Elsevier eBooks · doi:10.1016/c2013-0-11696-0 · Cited by 418 · see citing works
Contribution à l’étude anatomopathologique et clinique des différents variétés de cécité verbale
Dejerine, J. (1892) · Max Planck Digital Library · Cited by 255 · see citing works
Alexia without agraphia or hemianopsia. Anatomical analysis of an autopsied case
GREENBLATT, S. H. (1973) · Brain · doi:10.1093/brain/96.2.307 · Cited by 149 · see citing works
A Case of the Isolation of the Language Function
Whitaker, H. (1976) · Elsevier eBooks · doi:10.1016/b978-0-12-746302-5.50008-6 · Cited by 136 · see citing works
Subangular alexia without agraphia or hemianopsia
Greenblatt, S. H. (1976) · Brain and Language · doi:10.1016/0093-934x(76)90019-5 · Cited by 102 · see citing works
Repetition in the transcortical aphasias
Davis, L., Foldi, N. S., Gardner, H., & Zurif, E. (1978) · Brain and Language · doi:10.1016/0093-934x(78)90060-3 · Cited by 46 · see citing works
(2012) · SpringerReference · doi:10.1007/springerreference_183697 · Cited by 46 · see citing works
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Specialization within the ventral stream: the case for the visual word form area
Cohen, L., & Dehaene, S. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2003.12.049 · Cited by 776 · see citing works
Cohen, L. (2003) · Cerebral Cortex · doi:10.1093/cercor/bhg079 · Cited by 400 · see citing works
The physiology of coloured hearing A PET activation study of colour-word synaesthesia
Paulesu, E., Harrison, J., Baron‐Cohen, S., Watson, J. D. G., Goldstein, L. H., Heather, J. D., Frackowiak, R. S. J., & Frith, C. (1995) · Brain · doi:10.1093/brain/118.3.661 · Cited by 215 · see citing works
The functional anatomy of single-word reading in patients with hemianopic and pure alexia
Leff, A. P., Crewes, H., Plant, G. T., Scott, S. K., Christopher Kennard, C., & Wise, R. J. S. (2001) · Brain · doi:10.1093/brain/124.3.510 · Cited by 179 · see citing works
Berthier, M. L. (2001) · Aphasiology · doi:10.1080/02687040042000179 · Cited by 62 · see citing works
The word-length effect in acquired alexia, and real and virtual hemianopia
Sheldon, C. A., Abegg, M. H., Sekunova, A., & Barton, J. J. S. (2012) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2012.01.020 · Cited by 47 · see citing works
Alexia without agraphia or hemianopia in parietal infarction.
Iragui, V. J., & Kritchevsky, M. (1991) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.54.9.841 · Cited by 28 · see citing works
Davous, P., & Boller, F. (1994) · Neuropsychologia · doi:10.1016/0028-3932(94)90108-2 · Cited by 21 · see citing works
Left occipital lobectomy and the preangular anatomy of reading*1
Greenblatt, S. H. (1990) · Brain and Language · doi:10.1016/0093-934x(90)90138-7 · Cited by 18 · see citing works
Creutzfeldt-Jakob Disease with Mixed Transcortical Aphasia: Insights into Echolalia
McPherson, S. E., Kuratani, J. D., Cummings, J. L., Shih, J. J., Mischel, P. S., & Vinters, H. V. (1994) · Behavioural Neurology · doi:10.1155/1994/601201 · Cited by 11 · see citing works
Transcortical mixed aphasia due the subcortical hemorrhage in the left parietooccipital lobe.
Maeshima, S., Komai, N., Nakai, M., Hyotani, G., & ITAKURA, T. (1990) · Shitsugoshō kenkyū/Shitsugoshou kenkyuu · doi:10.2496/apr.10.205 · Cited by 2 · see citing works
Color anomia: Clinical, developmental, and neuropathological issues
Mattocks, L. F., & Hynd, G. W. (1986) · Developmental Neuropsychology · doi:10.1080/87565648609540333
Kerr, K. (1986) · doi:10.31390/gradschool_disstheses.4306
Self-citation
- Authors
- Pirozzolo, F. J., Kerr, K. L., Obrzut, J. E., Morley, G. K., Haxby, J. V., & Lundgren, S.
- Venue
- Journal of Neurology, Neurosurgery & Psychiatry
- Publisher
- BMJ
- Published
- 1981-02-01
- Volume
- 44
- Issue
- 2
- Pages
- 152-155
- ISSN
- 0022-3050 (ISSN-L)
- PMC
- PMC490848
- OpenAlex
- W1969358302
- Cited by
- 13
- References
- 8
- Citations by year
- 2012: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Neurology Neurosurgery & Psychiatry (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Social Sciences › Psychology › Developmental and Educational Psychology › Reading and Literacy Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hemispheric Asymmetry in Neuroscience
- Keywords
- alexia without agraphia, naming disorders, echopraxia, auditory comprehension, neurolinguistic assessment
- MeSH terms
- Aphasia, Cerebral Hemorrhage, Dyslexia, Acquired, Humans, Male, Middle Aged, Neuropsychological Tests, Parietal Lobe, Psycholinguistics, Syndrome
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