Cited by 103Electrolyte and hormonal disordersCerebrospinal fluid and hydrocephalusNeuroendocrine regulation and behavior

Cerebrospinal-fluid vasopressin in neurological and psychiatric-disorders

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Sorensen, P S, Gjerris, A, Hammer, M·1985·Journal of Neurology, Neurosurgery & Psychiatry

Abstract

Vasopressin was determined in CSF and plasma of 243 patients with different neurological and psychiatric disorders, including control patients. CSF vasopressin was significantly higher in patients with high pressure hydrocephalus, intracranial tumour, benign intracranial hypertension, intracranial haemorrhage, ischaemic stroke, and craniocerebral trauma. In patients with primary degenerative dementia, CSF vasopressin was lower than in control patients. Among patients with psychiatric disorders, CSF vasopressin was increased in manic patients, while in patients with depression CSF concentration of this hormone did not differ from that found in controls. However, an increase in CSF vasopressin level was found in patients recovering from a depression. The clinical significance of changes in CSF vasopressin concentrations in groups of patients with neurological and psychiatric disorders is still unknown.

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Research works printed but not linked: 5

  1. Brownfield MS, Kozlowski GP. The hyothalamochoroi- dal tract. I. Immunohistochemical demonstration of neurophysin pathways to telencephalic choroid plex- uses and cerebrospinal fluid. Cell Tissue Res 1977; 178:111-27.
  2. De Wied D, van Wimersma Greidanus TB, Bohus B, Urban I, Gispen WH. Vasopressin and memory con- solidation. In: Corner MA, Swaab DF, eds. Perspec- tives in Brain Research. Progress in Brain Research. Amsterdam Elsevier. 1976:181-94.
  3. "Gold PW, Goodwin FK, Reus VI. Vasopressin in affec- tive illness. Lancet 1978;1: 1233-6.
  4. 41Sorensen PS, Vilhardt H, Gjerris F, Warberg J. Imper- meability of the blood-cerebrospinal fluid barrier to l-deamino-8-D-arginine-vasopressin (DDAVP) in man. Eur J Clin Invest (In press).
  5. Gold PW, Goodwin FK, Post R, Robertson GL. Vasop- ressin function in depression and mania. Psychophar- macol Bull 198 1; 17:7-9.

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Authors
Sorensen, P. S., Gjerris, A., & Hammer, M.
Venue
Journal of Neurology, Neurosurgery & Psychiatry
Publisher
BMJ
Published
1985-01-01
Volume
48
Issue
1
Pages
50-57
ISSN
0022-3050 (ISSN-L)
OpenAlex
W2048921697
Cited by
103
References
46
Citations by year
2026: 2 · 2024: 2 · 2021: 2 · 2019: 1 · 2018: 4 · 2017: 4 · 2016: 1 · 2014: 5 · 2013: 2 · 2012: 2
FWCI
8.55
Type
journal article
Language
en
Open access
Locations
  • Journal of Neurology Neurosurgery & Psychiatry (publishedVersion)
  • PubMed Central (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed (publishedVersion)
  • HighWire Press Open Archive (submittedVersion)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Electrolyte and hormonal disorders
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Cerebrospinal fluid and hydrocephalus
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
Keywords
vasopressin, cerebrospinal fluid, plasma vasopressin, intracranial tumors, idiopathic intracranial hypertension, intracranial hemorrhage, ischemic stroke, traumatic brain injury, degenerative dementia, mania, depression, recovery from depression
MeSH terms
Adult, Aged, Arginine Vasopressin, Basal Ganglia Diseases, Mental Disorders, Bipolar Disorder, Brain Diseases, Brain Neoplasms, Cerebral Hemorrhage, Cerebral Infarction, Dementia, Depressive Disorder, Female, Humans, Hydrocephalus, Hydrocephalus, Normal Pressure, Intracranial Pressure, Male, Middle Aged, Multiple Sclerosis, Pseudotumor Cerebri, Schizophrenia

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