Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 316

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study

Open access
Shields, Adrian, Faustini, Sian E, Perez-Toledo, Marisol, Jossi, Sian, Aldera, Erin, Allen, Joel D, Al-Taei, Saly, Backhouse, Claire, Bosworth, Andrew, Dunbar, Lyndsey A, Ebanks, Daniel, Emmanuel, Beena, Garvey, Mark, Gray, Joanna, Kidd, I Michael, McGinnell, Golaleh, McLoughlin, Dee E, Morley, Gabriella, O'Neill, Joanna, Papakonstantinou, Danai, Pickles, Oliver, Poxon, Charlotte, Richter, Megan, Walker, Eloise M, Wanigasooriya, Kasun, Watanabe, Yasunori, Whalley, Celina, Zielinska, Agnieszka E, Crispin, Max, Wraith, David C, Beggs, Andrew D, Cunningham, Adam F, Drayson, Mark T, Richter, Alex G·2020·Thorax

Abstract

Objective: To determine the rates of asymptomatic viral carriage and seroprevalence of SARS-CoV-2 antibodies in healthcare workers. Design: A cross-sectional study of asymptomatic healthcare workers undertaken on 24/25 April 2020. Setting: University Hospitals Birmingham NHS Foundation Trust (UHBFT), UK. Participants: 545 asymptomatic healthcare workers were recruited while at work. Participants were invited to participate via the UHBFT social media. Exclusion criteria included current symptoms consistent with COVID-19. No potential participants were excluded. Intervention: Participants volunteered a nasopharyngeal swab and a venous blood sample that were tested for SARS-CoV-2 RNA and anti-SARS-CoV-2 spike glycoprotein antibodies, respectively. Results were interpreted in the context of prior illnesses and the hospital departments in which participants worked. Main outcome measure: Proportion of participants demonstrating infection and positive SARS-CoV-2 serology. Results: The point prevalence of SARS-CoV-2 viral carriage was 2.4% (n=13/545). The overall seroprevalence of SARS-CoV-2 antibodies was 24.4% (n=126/516). Participants who reported prior symptomatic illness had higher seroprevalence (37.5% vs 17.1%, χ 2 =21.1034, p<0.0001) and quantitatively greater antibody responses than those who had remained asymptomatic. Seroprevalence was greatest among those working in housekeeping (34.5%), acute medicine (33.3%) and general internal medicine (30.3%), with lower rates observed in participants working in intensive care (14.8%). BAME (Black, Asian and minority ethnic) ethnicity was associated with a significantly increased risk of seropositivity (OR: 1.92, 95% CI 1.14 to 3.23, p=0.01). Working on the intensive care unit was associated with a significantly lower risk of seropositivity compared with working in other areas of the hospital (OR: 0.28, 95% CI 0.09 to 0.78, p=0.02). Conclusions and relevance: We identify differences in the occupational risk of exposure to SARS-CoV-2 between hospital departments and confirm asymptomatic seroconversion occurs in healthcare workers. Further investigation of these observations is required to inform future infection control and occupational health practices.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1136/thoraxjnl-2020-215414

Cites

18 of 18 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 18 references

Cited by

See all 316

Metadata

Authors
Shields, A., Faustini, S. E., Perez-Toledo, M., Jossi, S., Aldera, E., Allen, J. D., Al-Taei, S., Backhouse, C., Bosworth, A., Dunbar, L. A., Ebanks, D., Emmanuel, B., Garvey, M., Gray, J., Kidd, I. M., McGinnell, G., McLoughlin, D. E., Morley, G., O'Neill, J., Papakonstantinou, D., Pickles, O., Poxon, C., Richter, M., Walker, E. M., Wanigasooriya, K., Watanabe, Y., Whalley, C., Zielinska, A. E., Crispin, M., Wraith, D. C., Beggs, A. D., Cunningham, A. F., Drayson, M. T., & Richter, A. G.
Venue
Thorax
Publisher
BMJ
Published
2020-09-11
Volume
75
Issue
12
Pages
1089-1094
ISSN
  • 0040-6376 (ISSN-L)
  • 1468-3296
OpenAlex
W3084708572
Cited by
316
References
18
FWCI
9.02
Type
journal article
Language
en
Open access
hybrid

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study. https://app.cochat.ai/papers/10.1136/thoraxjnl-2020-215414
The paper
Shields, A., Faustini, S. E., Perez-Toledo, M., Jossi, S., Aldera, E., Allen, J. D., Al-Taei, S., Backhouse, C., Bosworth, A., Dunbar, L. A., Ebanks, D., Emmanuel, B., Garvey, M., Gray, J., Kidd, I. M., McGinnell, G., McLoughlin, D. E., Morley, G., O'Neill, J., . . . Richter, A. G. (2020). SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study. Thorax. https://doi.org/10.1136/thoraxjnl-2020-215414

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.