Implication of the hypothalamic-pituitary-adrenal axis in the physiopathology of depression

Two receptor systems for corticosterone in rat brain: Microdistribution and differential occupation

REUL, J. M. H. M., & KLOET, E. R. D. (1985) · Endocrinology · doi:10.1210/endo-117-6-2505 · Cited by 2,580

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

Tronche, F., Kellendonk, C., Kretz, O., Gass, P., Anlag, K., Orban, P. C., Bock, R., Klein, R., & Schütz, G. (1999) · Nature Genetics · doi:10.1038/12703 · Cited by 1,841

The Role of the Hippocampus in Feedback Regulation of the Hypothalamic-Pituitary-Adrenocortical Axis*

JACOBSON, L., & SAPOLSKY, R. (1991) · Endocrine Reviews · doi:10.1210/edrv-12-2-118 · Cited by 1,739

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

Nemeroff, C. B., Widerlöv, E., Bissette, G., Walléus, H., Karlsson, I., Eklund, K., Kilts, C. D., Loosen, P. T., & Vale, W. (1984) · Science · doi:10.1126/science.6334362 · Cited by 1,485

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

Dunn, A. J., & Berridge, C. W. (1990) · Brain Research Reviews · doi:10.1016/0165-0173(90)90012-d · Cited by 1,352

Physiology and pharmacology of corticotropin-releasing factor.

Owens, M. J., & Nemeroff, C. B. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06673-6 · Cited by 1,147

Antidepressants and Hypothalamic-Pituitary-Adrenocortical Regulation

HOLSBOER, F., & Barden, N. (1996) · Endocrine Reviews · doi:10.1210/edrv-17-2-187 · Cited by 860

Brain corticosteroid receptor balance and homeostatic control

de Kloet, E. R. (1991) · Frontiers in Neuroendocrinology · Cited by 842

Psychopharmacology: The Fourth Generation of Progress

Kramlinger, K. G. (1995) · Mayo Clinic Proceedings · doi:10.4065/70.10.1021-a · Cited by 779

Responses to Corticotropin-Releasing Hormone in the Hypercortisolism of Depression and Cushing's Disease

Gold, P. W., Loriaux, D. L., Roy, A., Kling, M. A., Calabrese, J. R., Kellner, C. H., Nieman, L. K., Post, R. M., Pickar, D., Gallucci, W. T., et al. (1986) · New England Journal of Medicine · doi:10.1056/nejm198605223142101 · Cited by 766

Activation of glucocorticoid receptors increases 5-HT2A receptor levels

Trajkovska, V., Kirkegaard, L., Krey, G., Marcussen, A. B., Thomsen, M. S., Chourbaji, S., Brandwein, C., Ridder, S., Halldin, C., Gass, P., et al. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.04.008 · Cited by 28

Mangiferin prevents corticosterone-induced behavioural deficits via alleviation of oxido-nitrosative stress and down-regulation of indoleamine 2,3-dioxygenase (IDO) activity

Luo, G.-Q., Liu, L., Gao, Q., Wu, X., Xiang, W., & Deng, W. (2017) · Neurological Research · doi:10.1080/01616412.2017.1310705 · Cited by 31

Aspects of Pain, Its Assessment and Evaluation from An Acupuncture Perspective

Lund, I., & Lundeberg, T. (2006) · Acupuncture in Medicine · doi:10.1136/aim.24.3.109 · Cited by 28

The influence of personality on the effect of iTBS after being stressed on cortisol secretion

Pulopulos, M. M., Witte, S. D., Vanderhasselt, M., Raedt, R. D., Schiettecatte, J., Anckaert, E., Salvador, A., & Baeken, C. (2019) · PLoS ONE · doi:10.1371/journal.pone.0223927 · Cited by 26

A bioactive compound from Polygala tenuifolia regulates efficiency of chronic stress on hypothalamic-pituitary-adrenal axis

Hu, Y., Liao, H., Liao, H.-B., Liu, P., Guo, D.-H., & Rahman, K. (2009) · Die Pharmazie · doi:10.31083/ph.2009.9580 · Cited by 26

Sensitivity of depression-like behavior to glucocorticoids and antidepressants is independent of forebrain glucocorticoid receptors

Vincent, M. Y., Hussain, R. J., Zampi, M. E., Sheeran, K., Solomon, M. B., Herman, J. P., Khan, A. A., & Jacobson, L. (2013) · Brain Research · doi:10.1016/j.brainres.2013.05.031 · Cited by 26

The Antidepressant and Cognitive Improvement Activities of the Traditional Chinese Herb Cistanche

Wang, D., Wang, H., & Gu, L. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/3925903 · Cited by 26

Could a blood test for PTSD and depression be on the horizon?

Aspesi, D., & Pinna, G. (2018) · Expert Review of Proteomics · doi:10.1080/14789450.2018.1544894 · Cited by 26

Migraine and depression: common pathogenetic and therapeutic ground?

Moschiano, F., D’Amico, D., Canavero, I., Pan, I., Micieli, G., & Bussone, G. (2011) · Neurological Sciences · doi:10.1007/s10072-011-0545-0 · Cited by 27

Microbiota-Gut-Brain Axis in Major Depression: A New Therapeutic Approach

Kim, I. B., Park, S., & Kim, Y. (2023) · Advances in experimental medicine and biology · doi:10.1007/978-981-19-7376-5_10 · Cited by 27

Psychological Factors Associated with Response to Treatment in Rheumatoid Arthritis

Santiago, T., Geenen, R., Jacobs, J. W. G., & Da, J. A. P. (2014) · Current Pharmaceutical Design · doi:10.2174/1381612820666140825124755 · Cited by 24

A Microbiome-Driven Approach to Combating Depression During the COVID-19 Pandemic

Ghannoum, M. A., Ford, M., Bonomo, R. A., Gamal, A., & McCormick, T. S. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.672390 · Cited by 24

Interaction with stressed mothers affects corticosterone levels in pups after reunion and impairs the response to dexamethasone in adult mice

Moles, A., Sarli, C., Bartolomucci, A., & D'Amato, F. R. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.01.003 · Cited by 27

Effects of escitalopram/quetiapine combination therapy versus escitalopram monotherapy on hypothalamic–pituitary–adrenal-axis activity in relation to antidepressant effectiveness

Nothdurfter, C., Schmotz, C., Sarubin, N., Baghai, T. C., Laenger, A., Lieb, M., Bondy, B., Rupprecht, R., & Schüle, C. (2014) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2014.01.013 · Cited by 23

Antidepressant-like effects of mineralocorticoid but not glucocorticoid antagonists in the lateral septum: Interactions with the serotonergic system

Mostalac-Preciado, C. R., de Gortari, P., & López‐Rubalcava, C. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.04.008 · Cited by 23

Behavioral and Biochemical Evidences for Antidepressant-Like Activity of Celastrus Paniculatus Seed Oil in Mice.

Valecha, R., & Dhingra, D. (2016) · Europe PMC (PubMed Central) · Cited by 23

Social determinants of perinatal mental health

Pardo, C., Watson, B., Pinkhasov, O., & Afable, A. (2024) · Seminars in Perinatology · doi:10.1016/j.semperi.2024.151946 · Cited by 23

The early postpartum period – Differences between women with and without a history of depression

Schnakenberg, P., Jo, H., Stickel, S., Habel, U., Eickhoff, S. B., Brodkin, E. S., Goecke, T. W., Votinov, M., & Chechko, N. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.01.056 · Cited by 22

Mouse Models of Depression

Dedic, N., Sandra, M., & Jan, M. (2011) · InTech eBooks · doi:10.5772/27498 · Cited by 27

Safety of Glucocorticoids in Rheumatoid Arthritis: Evidence from Recent Clinical Trials

Santiago, T., & da Silva, J. A. P. (2014) · NeuroImmunoModulation · doi:10.1159/000362726 · Cited by 22

Antidepressant-Like Effects of Shuyusan in Rats Exposed to Chronic Stress: Effects on Hypothalamic-Pituitary-Adrenal Function

Chen, L., Chen, M., Wang, F., Sun, Z., Quanzhi, H., Geng, M., Chen, H., & Duan, D. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/940846 · Cited by 22

Reduced vasopressin receptors activation mediates the anti-depressant effects of fluoxetine and venlafaxine in bulbectomy model of depression

Poretti, M. B., Sawant, R. S., Rask‐Andersen, M., de Cúneo, M. F., Schiöth, H. B., Pérez, M. F., & Carlini, V. P. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4187-4 · Cited by 22

Purpurin exerted antidepressant-like effects on behavior and stress axis reactivity: evidence of serotonergic engagement

Ma, L., Hu, P. L., Zhang, J., Cui, W., & Zhao, X. (2020) · Psychopharmacology · doi:10.1007/s00213-019-05422-w · Cited by 21

Neuroendocrine predictors of the evolution of depression

Duval, F., Mokrani, M., Monreal, J. A., Schulz, P., Champeval, C., & Macher, J. P. (2005) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2005.7.3/fduval · Cited by 22

The effect of exercise on depression and gut microbiota: Possible mechanisms

Yao, M., Qu, Y., Zheng, Y., & Guo, H. (2024) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2024.111130 · Cited by 26

Impact of sex and depressed mood on the central regulation of cardiac autonomic function

Garcia, R. G., Marečková, K., Holsen, L. M., Cohen, J. E., Whitfield, S., Napadow, V., Barbieri, R., & Goldstein, J. M. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0651-x · Cited by 21

Role and Function of Endocannabinoid System in Major Depressive Disease

Yarar, E. (2020) · Medical Cannabis and Cannabinoids · doi:10.1159/000511979 · Cited by 21

Gut feelings: bacteria and the brain.

Foster, J. A. (2013) · Europe PMC (PubMed Central) · Cited by 21

Extracellular Matrix and Oxidative Phosphorylation: Important Role in the Regulation of Hypothalamic Function by Gut Microbiota

Qi, X., Zhong, X., Xu, S., Zeng, B., Chen, J., Zang, G., Zeng, L., Bai, S., Zhou, C., Wei, H., et al. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00520 · Cited by 21

Pubertal maturation and cortisol level in response to a novel social environment among female adolescents

Blumenthal, H., Leen‐Feldner, E. W., Badour, C. L., Trainor, C. D., & Babson, K. A. (2014) · Journal of Adolescence · doi:10.1016/j.adolescence.2014.06.005 · Cited by 21

Translating depression biomarkers for improved targeted therapies

Bredt, D. S., Furey, M. L., Chen, G., Lovenberg, T., Drevets, W. C., & Manji, H. K. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.09.013 · Cited by 21

Application of Complementary and Alternative Medicine on Neurodegenerative Disorders: Current Status and Future Prospects

Ip, S., Tsim, K. W. K., Chan, K., & Bauer, R. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/930908 · Cited by 21

The Effects of Gender Differences in Patients with Depression on Their Emotional Working Memory and Emotional Experience

Li, M., Lu, S., Wang, G., & Zhong, N. (2015) · Behavioural Neurology · doi:10.1155/2015/807343 · Cited by 20

Higher Concentration of Adrenocorticotropic Hormone Predicts Post-Stroke Depression

Wang, Y., Wang, H., Sun, W., Miao, J., Liang, W., Qiu, X., Lan, Y., Pan, C., Li, G., Zhao, X., et al. (2022) · Clinical Interventions in Aging · doi:10.2147/cia.s356361 · Cited by 19

Structure-activity relationships of serotonin 5-HT7 receptors ligands: A review

Thirumaran, S.-L., Lepailleur, A., & Rochais, C. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.111705 · Cited by 19

Psychiatric Problems in Pulmonary Tuberculosis: Depression and Anxiety

Lara-Espinosa, J. V., & Hernández‐Pando, R. (2021) · Journal of Tuberculosis Research · doi:10.4236/jtr.2021.91003 · Cited by 19

Deficits in KCC2 and activation of the HPA axis lead to depressionlike behavior following social defeat

Miller, S., & Maguire, J. L. (2014) · Hormonal Studies · doi:10.7243/2052-8000-2-2 · Cited by 20

Psychosocial and Biological Indicators of Depression in the Caregiving Population

Clark, M. C., Nicholas, J., Wassira, L. N., & Gutierrez, A. P. (2011) · Biological Research For Nursing · doi:10.1177/1099800411414872 · Cited by 20

Effects of different probiotic strains B. lactis, L. rhamnosus and L. reuteri on brain-intestinal axis immunomodulation in an endotoxin-induced inflammation

Michels, M., Jesus, G. F. A., Abatti, M. R., Córneo, E. D. S., Cucker, L., Borges, H. D. M., Matos, N. D. S., Rocha, L. B., Dias, R., Simon, C. S., et al. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-02906-3 · Cited by 21

Evolutionarily conserved gene expression patterns for affective disorders revealed using cross-species brain transcriptomic analyses in humans, rats and zebrafish

Demin, K. A., Krotova, N. A., Ilyin, N. P., Galstyan, D. S., Kolesnikova, T. O., Strekalova, T. V., de Abreu, M. S., Petersen, E. V., Zabegalov, K. N., & Kalueff, A. V. (2022) · Scientific Reports · doi:10.1038/s41598-022-22688-x · Cited by 19

Baicalin improves the energy levels in the prefrontal cortex of mice exposed to chronic unpredictable mild stress

Lu, S., Li, C., Jin, X., Zhu, L., Shen, J.-D., Bai, M., Li, Y., & Xu, E. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e12083 · Cited by 17

Fluvoxamine increased glutamate release by activating both 5-HT(3) and sigma-1 receptors in prelimbic cortex of chronic restraint stress C57BL/6 mice.

Fu, Y.-M., Yu, S.-Y., Guo, X.-Y., Li, X., Li, T.-Y., Li, H.-F., & Dong, Y. (2012) · Biochimica et Biophysica Acta · doi:10.1016/j.bbamcr.2012.01.008 · Cited by 18

Effects of some new antidepressant drugs on the glucocorticoid receptor-mediated gene transcription in fibroblast cells.

Augustyn, M., Otczyk, M., Budziszewska, B., Jagła, G., Nowak, W., Basta‐Kaim, A., Jaworska-Feil, L., Kubera, M., Tetich, M., Leśkiewicz, M., et al. (2005) · PubMed · Cited by 17

Incidence of adverse psychiatric events during treatment of inflammatory bowel disease with biologic therapies: A systematic review

Jain, A., Marrie, R. A., Shafer, L. A., Graff, L. A., Patten, S. B., El-Gabalawy, R., Sareen, J., Bolton, J. M., Fisk, J. D., & Bernstein, C. N. (2020) · Crohn's & Colitis 360 · doi:10.1093/crocol/otz053 · Cited by 16

Adaptations in Mitochondrial Function Induced by Exercise: A Therapeutic Route for Treatment-Resistant Depression

Ramos‐Jiménez, A., Rubio-Valles, M., Ramos-Hernández, J. A., González-Rodríguez, E., & Moreno-Brito, V. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26178697 · Cited by 20

Biomarkers for Deep Brain Stimulation in Animal Models of Depression

Yuen, J., Rusheen, A. E., Price, J. B., Barath, A. S., Shin, H., Kouzani, A. Z., Berk, M., Blaha, C. D., Lee, K. H., & Oh, Y. (2021) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.13483 · Cited by 16

Bridging the Mind and Gut: Uncovering the Intricacies of Neurotransmitters, Neuropeptides, and their Influence on Neuropsychiatric Disorders

Gupta, S., Dinesh, S., & Sharma, S. (2024) · Central Nervous System Agents in Medicinal Chemistry · doi:10.2174/0118715249271548231115071021 · Cited by 18

Potential role of gut microbiota in major depressive disorder: A review

Khaledi, M., Sameni, F., Gholipour, A., Shahrjerdi, S., Golmohammadi, R., Ghaleh, H. E. G., Poureslamfar, B., Hemmati, J., Mobarezpour, N., Milasi, Y. E., et al. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e33157 · Cited by 18

Effects of PB190 and PB212, new σ receptor ligands, on glucocorticoid receptor-mediated gene transcription in LMCAT cells

Skuza, G., Szymańska, M., Budziszewska, B., Abate, C., & Berardi, F. (2011) · Pharmacological Reports · doi:10.1016/s1734-1140(11)70722-8 · Cited by 15

Chronic itch impairs mood and HPA axis function in mice: modulation by CRFR1 antagonist

Zhao, X., Yu, C., Ye, F., Wang, Y., Mei, Q., Ma, Q., Cui, W., & Zhou, W. (2018) · Pain · doi:10.1097/j.pain.0000000000001319 · Cited by 17

Developing More Efficacious Antidepressant Medications: Improving and Aligning Preclinical and Clinical Assessment Tools

Cryan, J. F., Sánchez, C., Dinan, T. G., & Borsini, F. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-373861-5.00007-2 · Cited by 17

Depression and generalized anxiety symptoms in idiopathic intracranial hypertension: Prevalence, under-reporting and effect on visual outcome

Donaldson, L., Dezard, V. A., Chen, M., & Margolin, E. (2021) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2021.120120 · Cited by 15

NASCIDOS PARA CORRER: A IMPORTÂNCIA DO EXERCÍCIO PARA A SAÚDE DO CÉREBRO

Vorkapic, C. F., Góis, R. S., Gomes, L. P. D. S., Britto, A., Afrânio, B., & Dantas, E. H. M. (2017) · Revista Brasileira de Medicina do Esporte · doi:10.1590/1517-869220172306175209 · Cited by 22

Health Disparities, Social Class, and Aging

Whitfield, K. E., Thorpe, R. J., & Szanton, S. L. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-380882-0.00013-9 · Cited by 15

Research trends in the field of the gut-brain interaction: Functional dyspepsia in the spotlight – An integrated bibliometric and science mapping approach

Zhang, T., Zhang, B., Ma, X., Zhang, J., Wei, Y., Wang, F., & Tang, X. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1109510 · Cited by 15

Hearing loss is associated with hippocampal atrophy and high cortisol/dehydroepiandrosterone sulphate ratio in older adults

Aoki, M., Okuda, H., Ishihara, H., Hayashi, H., Ohashi, T., Nishihori, T., & Kuze, B. (2020) · International Journal of Audiology · doi:10.1080/14992027.2020.1831703 · Cited by 13

Behavioural Consequences of P‐Glycoprotein Deficiency in Mice, with Special Focus on Stress‐Related Mechanisms

Schoenfelder, Y., Hiemke, C., & Schmitt, U. (2012) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2012.02278.x · Cited by 14

Sex-dependent consequences of pre-pubertal gonadectomy: Social behavior, stress and ethanol responsivity

Kim, E. U., & SPEAR, L. P. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.09.022 · Cited by 13

Impaired hypothalamo-pituitary-adrenal axis in patients with ankylosing spondylitis

Kebapçılar, L., Bilgir, O., Alacacıoğlu, A., Yıldız, Y., Taylan, A., Günaydın, R., Yüksel, A., Karaca, B., & Sarı, İ. (2009) · Journal of Endocrinological Investigation · doi:10.1007/bf03346548 · Cited by 13

Morbidity and Mortality in People with Serious Mental

Parks, J., Svendsen, D. P., Singer, P., & Foti, M. E. (2006) · Cited by 13

Hormonal response to buspirone is not impaired in major depression

Navinés, R., Gómez‐Gil, E., Martín‐Santos, R., de Osaba, M. J. M., Escolar, G., & Gastó, C. (2007) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.862 · Cited by 13

Evaluation of pituitary function in the fatigued patient: a review of 59 cases

Greenfield, J. R., & Samaras, K. (2005) · European Journal of Endocrinology · doi:10.1530/eje.1.02010 · Cited by 12

Sleep disturbances and excessive daytime sleepiness in migraine: A comparison between comorbidities and disability

Şengül, Y., Sengul, H., Bakım, B., Yucekaya, S. K., Yücel, S., & Akgün, M. (2014) · Sleep and Biological Rhythms · doi:10.1111/sbr.12087 · Cited by 11

Effect of some antidepressants on the low corticosterone concentration-induced gene transcription in LMCAT fibroblast cells.

Otczyk, M., Mulyk, K., Budziszewska, B., Jaworska-Feil, L., Basta‐Kaim, A., Kubera, M., Jagła, G., Nowak, W., & Lasoń, W. (2008) · PubMed · Cited by 11

Mothering matters: Towards a better understanding of disrupted infant-caregiver relationships in both mother and offspring

Rincón‐Cortés, M. (2024) · Neurobiology of Stress · doi:10.1016/j.ynstr.2024.100701 · Cited by 11

Paroxetine ameliorates changes in hippocampal energy metabolism in chronic mild stress-exposed rats

Abdel-Tawab, A. M., Khedr, L. H., Nassar, N. N., & Eldenshary, E. E.-D. S. (2015) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s87089 · Cited by 11

Cortisol response to individualised graded insulin infusions: a reproducible biomarker for CNS compounds inhibiting HPA activation

Chen, C., Willis, B. A., Mooney, L., Ong, G. K., Lim, C. N., Lowe, S. L., Tauscher‐Wisniewski, S., Cutler, G. B., & Wiss, S. D. (2010) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2010.03781.x · Cited by 10

Resilient and depressive-like rats show distinct cognitive impairments in the touchscreen paired-associates learning (PAL) task

Martis, L., Brision, C., Holmes, M. C., & Wiborg, O. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.08.014 · Cited by 13

The Role of Gut Microbiota in the Antidepressant Effects of Ketamine

Wang, Y., Xu, X., Luo, A., & Yang, C. (2020) · Springer eBooks · doi:10.1007/978-981-15-2902-3_8 · Cited by 10

Mutation screen and association analysis of the glucocorticoid receptor gene (NR3C1) in childhood‐onset mood disorders (COMD)

Mill, J. S., Wigg, K., Burcescu, I., Vetró, Á., Kiss, E., Kapornai, K., Tamás, Z., Baji, I., Gádoros, J., Kennedy, J. L., et al. (2008) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30909 · Cited by 10

Dorsal hypothalamic dopaminergic neurons play an inhibitory role in the hypothalamic‐pituitary‐adrenal axis via activation of D2R in mice

Di, T., Chen, P., Yuan, Z., Wang, Y., Sha, S., & Chen, L. (2018) · Acta Physiologica · doi:10.1111/apha.13187 · Cited by 10

Evidence for the contribution of vasopressin V1B receptors in the pathophysiology of depression

Guan, W., Wang, Q., & Sheng, X.-M. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116672 · Cited by 10

Gut microbiota in anxiety and depression: mechanisms, drug interactions, and therapeutic implications

Fatimi, H. E., El‐Mansoury, B., Tinakoua, A., Ndayambaje, M., Zaid, Y., Khalki, H., & Khalki, L. (2025) · Pharmacological Reports · doi:10.1007/s43440-025-00759-w · Cited by 10

The development and tendency of depression researches: Viewed from the microbiota-gut-brain axis

Liang, S., Wu, X., Xu, H., Niu, Y., & Jin, F. (2018) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/n972017-01182 · Cited by 8

Chronic corticosterone treatment impairs trace conditioning in rats with a neonatal medial prefrontal cortex lesion

Enkel, T., & Koch, M. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.04.033 · Cited by 9

Depression and the hypothalamic-pituitary-adrenal axis: increasing the scope

Andreatini, R. (2012) · Acta Neuropsychiatrica · doi:10.1111/j.1601-5215.2011.00645.x · Cited by 9

Age-Related Changes in Gut Health and Behavioral Biomarkers in a Beagle Dog Population

Fernández-Pinteño, A., Pilla, R., Suchodolski, J. S., Apper, E., Torre, C., Salas, A., & Manteca, X. (2025) · Animals · doi:10.3390/ani15020234 · Cited by 10

Comparative evaluation of natural neuroprotectives and their combinations on chronic immobilization stress-induced depression in experimental mice

Ibrahim, I. M., Alsieni, M., Almalki, S. G., Alqurashi, Y. E., & Kumar, V. (2022) · 3 Biotech · doi:10.1007/s13205-022-03438-2 · Cited by 8

Sildenafil, alone and in combination with imipramine or escitalopram, display antidepressant-like effects in an adrenocorticotropic hormone-induced (ACTH) rodent model of treatment-resistant depression

Saayman, J. L. B., Harvey, B. H., Wegener, G., & Brink, C. B. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176434 · Cited by 7

Expression of glucocorticoid and mineralocorticoid receptor genes co-varies with a stress-related colour signal in barn owls

Béziers, P., Ducrest, A., San‐Jose, L. M., Simon, C., & Roulin, A. (2019) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2019.113224 · Cited by 8

Construction of antibiotic-induced depression mice model and the function of intestinal microbiota

Deng, H., Yu, Y., Sha, Q., Sun, W., Liang, L., Ren, F., Ji, H., Shen, X., & Fan, X. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1093486 · Cited by 11

Noradrenergic activity regulated dexamethasone-induced increase of 5-HT3 receptor-mediated glutamate release in the rat's prelimbic cortex

Zhang, X., Kan, Q., Fu, Y., Liu, S., Dai, Z.-P., & Dong, Y. W. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2012.08.006 · Cited by 8

Roles of monoaminergic, antioxidant defense and neuroendocrine systems in antidepressant-like effect of Cnestis ferruginea Vahl ex DC (Connaraceae) in rats

Ishola, I. O., Akinleye, M. O., Oduola-Akande, M. D., & Adeyemi, O. O. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.06.054 · Cited by 8

Shuyusan-containing serum protects SH-SY5Y cells against corticosterone-induced impairment.

Chen, L., Sun, Z., Wang, F., Cheng-yong, X., Geng, M., Chen, H., & Duan, D. (2013) · PubMed Central · doi:10.3969/j.issn.1673-5374.2013.22.005 · Cited by 8

Effects of social stress and clomipramine on emotional memory in mice

Duque, A., Vinader‐Caerols, C., & Monleón, S. (2016) · Acta Neurobiologiae Experimentalis · doi:10.21307/ane-2017-022 · Cited by 8

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Şair, A., Şair, Y. B., Akyol, A., & Sevinçok, L. (2020) · Women & Health · doi:10.1080/03630242.2020.1815930 · Cited by 7

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Reyes, A. A., & Chandler, D. J. (2023) · Neuroglia · doi:10.3390/neuroglia4020007 · Cited by 9

N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls

Krogh, J., Ströhle, A., Westrin, Å., Klausen, T. W., Jørgensen, M. B., & Nordentoft, M. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.09.009 · Cited by 7

Psychoneurointracrinology: The Embodied Self

Gordon, S. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7239-1_5 · Cited by 6

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Goldstein, J. M., Holsen, L. M., Handa, R. J., & Tobet, S. A. (2012) · Research and perspectives in endocrine interactions · doi:10.1007/978-3-642-33721-5_10 · Cited by 7

Cortisol Responses to Psychosocial Stress: The Role of Childhood Maltreatment and Depression.

Rao, U., & Morris, M. C. (2015) · PubMed · Cited by 6

Type, Topography, and Sequelae of Neuropathological Changes Shaping Clinical Phenotype of Autism

Węgiel, J., Wısnıewskı, T., Chauhan, A., Chauhan, V. P. S., Kuchna, I., Nowicki, K., Imaki, H., Wegiel, J., Ma, S., Wierzba‐Bobrowicz, T., et al. (2009) · CRC Press eBooks · doi:10.1201/9781420068870-c1 · Cited by 6

Depression, family and immunity: influence of humoral immunity on family relationships and on the severity of depression.

Tomasović, S., Sremec, J., Košćak, J., Klepac, N., Draganić, P., & Bielen, I. (2016) · PubMed · Cited by 6

Universidade Federal do Rio Grande do Sul Faculdade de Medicina Programa de Pós-graduação em Ciências Médicas: Endocrinologia, Metabolismo e Nutrição

Doutorado, T. D. (2008) · Cited by 6

Sleep, Cognitive and Mood Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Wallis, A., Jackson, M. L., Ball, M., Lewis, D. P., & Bruck, D. (2017) · Wiley eBooks · doi:10.1002/9781118993811.ch31 · Cited by 7

Design and validation of novel brain-penetrant HCN channel inhibitors to ameliorate social stress-induced susceptible phenotype

Teichman, E. M., Hu, J., Lin, H.-Y., Fisher-Foye, R. L., Blando, A., Hu, X., Kaniskan, H. Ü., Montgomery, S. E., Cai, M., Parise, L. F., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-02972-8 · Cited by 5

Allopregnanolone and intrusive memories: A potential therapeutic target for PTSD treatment?

Hamzah, K. A., Lipp, O. V., & Ney, L. J. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111168 · Cited by 6

Relationships among endocrine and signaling-related responses to antidepressants in human monocytic U-937 blood cells: Analysis of factors and response patterns

Gebhardt, S., Heiser, P., Fischer, S., Schneyer, T., Krieg, J.-C., & Vedder, H. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.07.002 · Cited by 5

Correlations of Aggressiveness with the Levels of Sex Hormones in Young Men; Validity of a Proposed Anthropometric Marker

Popova, L. D., Vasilyeva, I., & Наконечна, О. А. (2018) · Neurophysiology · doi:10.1007/s11062-018-9734-2 · Cited by 5

The Neuroendocrinology of Anhedonia

Taylor, G. T., Cabrera, O. H., & Hoffman, J. L. (2014) · Springer eBooks · doi:10.1007/978-94-017-8591-4_10 · Cited by 5

The hypothalamic pituitary adrenal axis, glucocorticoid receptor function and relevance to depression. [Portuguese]

Juruena, M. F., Cleare, A. J., & Pariante, C. M. (2004) · Research Portal (King's College London)

Antidepressant Actions on Glucocorticoid Receptors

Yau, J. L. W., & Seckl, J. R. (2007) · Elsevier eBooks · doi:10.1016/b978-012373947-6.00037-4 · Cited by 1

Involvement and role of antidepressant drugs of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor function.

Nikisch, G. (2009) · PubMed · Cited by 41

Regulation of corticosteroid receptor gene expression in depression and antidepressant action.

Barden, N. (1999) · PubMed Central · Cited by 66

The glucocorticoid receptor: Pivot of depression and of antidepressant treatment?

Anacker, C., Zunszain, P. A., Carvalho, L. A., & Pariante, C. M. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.03.007 · Cited by 592