Cited by 54,751Lipid metabolism and biosynthesisEdible Oils Quality and AnalysisFood Nutrient Composition and Product Development

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Bligh, E. G., Dyer, W. J.·1959·Canadian Journal of Biochemistry and Physiology

DOI 10.1139/o59-099

Open this paper in CoChat — free account

Abstract

Lipid decomposition studies in frozen fish have led to the development of a simple and rapid method for the extraction and purification of lipids from biological materials. The entire procedure can be carried out in approximately 10 minutes; it is efficient, reproducible, and free from deleterious manipulations. The wet tissue is homogenized with a mixture of chloroform and methanol in such proportions that a miscible system is formed with the water in the tissue. Dilution with chloroform and water separates the homogenate into two layers, the chloroform layer containing all the lipids and the methanolic layer containing all the non-lipids. A purified lipid extract is obtained merely by isolating the chloroform layer. The method has been applied to fish muscle and may easily be adapted to use with other tissues.

Integrity signals

Registry

Crossref · 10.1139/o59-099

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES
Folch, J., Lees, M., & Stanley, G. H. S. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64849-5 · Cited by 65,189
PREPARATION OF LIPIDE EXTRACTS FROM BRAIN TISSUE
Folch, J., Ascoli, I., Lees, M. B., Meath, J. A., & Lebaron, F. N. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55987-1 · Cited by 1,341
Storage of Frozen Plaice Fillets
Dyer, W. J., & Morton, M. L. (1956) · Journal of the Fisheries Research Board of Canada · doi:10.1139/f56-007 · Cited by 69
Self-citation
Experimental Determination of Binodal Curves, Plait Points, and Tie Lines, in 50 Systems, each consisting of Water and Two Organic Liquids
Bonner, W. D. (1910) · The Journal of Physical Chemistry · doi:10.1021/j150116a004 · Cited by 46
Acetone–Water Mixtures for the Extraction and Rapid Estimation of Fats of Biological Materials, Particularly Fish Products
Dambergs, N. (1956) · Journal of the Fisheries Research Board of Canada · doi:10.1139/f56-045 · Cited by 18

Show all 5 references

Research works printed but not linked: 1

BANCROFT W., 1895, Phys. Iiev., 3, 1

Sorted by citations

Items 12,401–12,500 of 48,846

Quantitative microanalysis of capsaicin, dihydrocapsaicin and nordihydrocapsaicin using mass fragmentography
Lee, K.-R., Suzuki, T., Kobashi, M., et al. (1976) · Journal of Chromatography A · doi:10.1016/s0021-9673(00)81108-5 · Cited by 52
Production of emulcyan byPhormidiumJ-1: its activity and function
Fattom, A., & Shilo, M. (1985) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1985.tb01125.x · Cited by 52
Extracellular lipid droplets promote hemozoin crystallization in the gut of the blood fluke Schistosoma mansoni
Soares, J. B. R. C., Maya‐Monteiro, C. M., Bittencourt-Cunha, P. R., Atella, G. C., Lara, F. A., d’Avila, J. C., Menezes, D., Vannier-Santos, M. A., de Oliveira, P. L., Egan, T. J., et al. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.03.054 · Cited by 52
Monocyte to Macrophage Differentiation Goes along with Modulation of the Plasmalogen Pattern through Transcriptional Regulation
Wallner, S., Grandl, M., Konovalova, T., Sigrüener, A., Kopf, T., Peer, M., Orsó, E., Liebisch, G., & Schmitz, G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094102 · Cited by 53
PROTEOLYSIS IN SALMON (SALMO SALAR) DURING COLD STORAGE; EFFECTS OF STORAGE TIME AND SMOKING PROCESS
LUND, K. E., & Nielsen, H. H. (2001) · Journal of Food Biochemistry · doi:10.1111/j.1745-4514.2001.tb00747.x · Cited by 52
Lipid production by Phaeodactylum tricornutum
Veloso, V., dos Reis, A. J. D., Gouveia, L., Fernandes, H. L., Empis, J., & Novais, J. M. (1991) · Bioresource Technology · doi:10.1016/0960-8524(91)90141-6 · Cited by 52
Temporal and spatial variability of sedimentary organic matter in sandy beaches on the northwest coast of the Iberian Peninsula
Incera, M., Cividanes, S. P., Lastra, M., et al. (2003) · Estuarine Coastal and Shelf Science · doi:10.1016/s0272-7714(03)00040-4 · Cited by 52
Polyunsaturated fatty acids in the psychrophilic bacterium Shewanella gelidimarina ACAM 456T: molecular species analysis of major phospholipids and biosynthesis of eicosapentaenoic acid
Nichols, D. S., Nichols, P. D., Russell, N. J., et al. (1997) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/s0005-2760(97)00068-4 · Cited by 52
Coulometric detection in high-performance liquid chromatographic analysis of cholesteryl ester hydroperoxides
Arai, H., Terao, J., Abdalla, D. S. P., et al. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(96)02062-x · Cited by 52
Developmental profile, isolation, and biochemical characterization of a novel lipoglycoheme-carrier protein from the American dog tick, Dermacentor variabilis (Acari: Ixodidae) and observations on a similar protein in the soft tick, Ornithodoros parkeri (Acari: Argasidae)
Gudderra, N. P., Neese, P. A., Sonenshine, D. E., et al. (2001) · Insect Biochemistry and Molecular Biology · doi:10.1016/s0965-1748(00)00122-3 · Cited by 52
Microbial Community Composition across the Great Plains
McCulley, R. L., & Burke, I. C. (2004) · Soil Science Society of America Journal · doi:10.2136/sssaj2004.1060 · Cited by 52
Incorporation of dietary sterols by the sea scallop Placopecten magellanicus (Gmelin) fed on microalgae
Napolitano, G. E., ACKMAN, R. G., & Silva-Serra, M. A. (1993) · Marine Biology · doi:10.1007/bf00349777 · Cited by 52
Expression of CD154 on renal cell carcinomas and effect on cell proliferation, motility and platelet‐activating factor synthesis
Bussolati, B., Russo, S., Deambrosis, I., et al. (2002) · International Journal of Cancer · doi:10.1002/ijc.10545 · Cited by 52
Lipid profile of the halophilic alga, Dunaliella salina
Tornabene, T. G., Holzer, G., & Peterson, S. L. (1980) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(80)90099-6 · Cited by 52
The biochemical characteristics and hatching performance of cultured and wild Atlantic salmon ( Salmo salar ) eggs
Srivastava, R., & Brown, J. A. (1991) · Canadian Journal of Zoology · doi:10.1139/z91-342 · Cited by 52
Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP‐activated protein kinase suppression
Osawa, Y., Seki, E., Kodama, Y., Suetsugu, A., Miura, K., Adachi, M., Ito, H., Shiratori, Y., Banno, Y., Olefsky, J. M., et al. (2010) · The FASEB Journal · doi:10.1096/fj.10-168351 · Cited by 55
Identification and Comparison of the Polar Phospholipids in Normal and Dry Eye Rabbit Tears by MALDI-TOF Mass Spectrometry
Ham, B. M., Cole, R. B., & Jacob, J. T. (2006) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.05-0756 · Cited by 52
The effect of growth rate and other growth conditions on the lipid composition of Escherichia coli
Arneborg, N., Salskov-Iversen, A., & Mathiasen, T. E. (1993) · Applied Microbiology and Biotechnology · doi:10.1007/bf00192091 · Cited by 52
Seasonal changes in the physiology of brook trout, Salvelinus fontinalis (Mitchill), in a sub‐Arctic river system
Cunjak, R. A., & Power, G. (1986) · Journal of Fish Biology · doi:10.1111/j.1095-8649.1986.tb04945.x · Cited by 52
Translocation of phospholipids from the inner to the outer membrane of Escherichia coli.
Donohue‐Rolfe, A., & Schaechter, M. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.4.1867 · Cited by 52
Interaction of low molecular weight group IIA phospholipase A 2 with apoptotic human T cells: role of heparan sulfate proteoglycans
Boilard, É., Bourgoin, S. G., Bernatchez, C., et al. (2003) · The FASEB Journal · doi:10.1096/fj.02-0938com · Cited by 52
Soil compaction–N interactions in barley: Root growth and tissue composition
Bingham, I. J., Bengough, A. G., & Rees, R. M. (2009) · Soil and Tillage Research · doi:10.1016/j.still.2009.10.008 · Cited by 52
Changes in yolk total proteins and lipid components and embryonic growth rates during lobster ( Homarus americanus ) egg development under a simulated seasonal temperature cycle
Sibert, V., Ouellet, P., & Br�thes, J. C. F. (2004) · Marine Biology · doi:10.1007/s00227-003-1287-1 · Cited by 52
Plasma fatty acids, prostaglandin F2alpha metabolite, and reproductive response in postpartum heifers fed rumen bypass fat.
Filley, S. J., Turner, H. A., & STORMSHAK, F. (2000) · Journal of Animal Science · doi:10.2527/2000.781139x · Cited by 52
Increased formation of lysophosphatidic acids by lysophospholipase D in serum of hypercholesterolemic rabbits
Tokumura, A., Kanaya, Y., Kitahara, M., et al. (2002) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)30173-5 · Cited by 52
Biodiversity and food web structure influence short‐term accumulation of sediment organic matter in an experimental seagrass system
Canuel, E. A., Spivak, A. C., Waterson, E. J., & Duffy, J. E. (2007) · Limnology and Oceanography · doi:10.4319/lo.2007.52.2.0590 · Cited by 52
Analysis of docosahexaenoic acid biosynthesis in Crypthecodinium cohnii by 13C labelling and desaturase inhibitor experiments
de Swaaf, M. E., de Rijk, T. C., van der Meer, P., Eggink, G., & Sijtsma, L. (2003) · Journal of Biotechnology · doi:10.1016/s0168-1656(03)00070-1 · Cited by 52
Oxidized Cholesteryl Linoleates Stimulate Endothelial Cells to Bind Monocytes via the Extracellular Signal–Regulated Kinase 1/2 Pathway
Huber, J., Boechzelt, H. G., Karten, B., Surboeck, M., Bochkov, V. N., Binder, B. R., Sattler, W., & Leitinger, N. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000012782.59850.41 · Cited by 51
Docosahexaenoic Acid Supplementation Decreases Remnant-Like Particle-Cholesterol and Increases the (n-3) Index in Hypertriglyceridemic Men
Kelley, D. S., Siegel, D., Vemuri, M., Chung, G. H., & Mackey, B. E. (2008) · Journal of Nutrition · doi:10.1093/jn/138.1.30 · Cited by 51
Lipid class content as an indicator of critical periods for survival in juvenile Atlantic salmon (Salmo salar)
Næsje, T., Thorstad, E. B., Forseth, T., et al. (2006) · Ecology Of Freshwater Fish · doi:10.1111/j.1600-0633.2006.00173.x · Cited by 52
Acyl-CoAs are functionally channeled in liver: potential role of acyl-CoA synthetase
Muoio, D. M., Lewin, T. M., Wiedmer, P., & Coleman, R. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.279.6.e1366 · Cited by 52
Solubilization of carotenoids from carrot juice and spinach in lipid phases: II. Modeling the duodenal environment
Rich, G. T., Faulks, R. M., Wickham, M. S. J., et al. (2003) · Lipids · doi:10.1007/s11745-003-1148-z · Cited by 52
Development of atherosclerosis in the diabetic BALB/c mice
Otero, P., Bonet, B., Herrera, E., & Rábano, A. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.02.024 · Cited by 53
Studies on lipase from Mucor javanicus
Hideko, I., Okuyama, H., Ikezawa, H., et al. (1975) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(75)90100-9 · Cited by 52
Crystalline arrays of the Escherichia coli sn-glycerol-3-phosphate acyltransferase, an integral membrane protein.
Wilkison, W. O., Walsh, J. P., Corless, J. M., & Bell, R. M. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67608-2 · Cited by 52
Effects of dietary saturated and unsaturated fatty acids on fecal bile acids and colon carcinogenesis induced by azoxymethane in rats.
坂口, 道., Minoura, T., 平松, 義., et al. (1986) · PubMed · Cited by 52
Metabolic Pathways in Methanococcus jannaschii and Other Methanogenic Bacteria
Sprott, G. D., Ekiel, I. H., & Patel, G. B. (1993) · Applied and Environmental Microbiology · doi:10.1128/aem.59.4.1092-1098.1993 · Cited by 52
Effect of ppGpp on Escherichia coli Cyclopropane Fatty Acid Synthesis Is Mediated through the RpoS Sigma Factor (ς S )
Eichel, J., Chang, Y., Riesenberg, D., et al. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.2.572-576.1999 · Cited by 52
Ceramide Triggers Meiotic Cell Cycle Progression in Xenopus Oocytes.
Strum, J. C., Swenson, K. I., Turner, J., et al. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.22.13541 · Cited by 52
Lipid Composition of Some Typical North Sea Copepods
Kattner, G., Krause, M. M., & Trahms, J. (1981) · Marine Ecology Progress Series · doi:10.3354/meps004069 · Cited by 52
Chylomicron remnants induce monocyte chemoattractant protein-1 expression via p38 MAPK activation in vascular smooth muscle cells
Domoto, K., Taniguchi, T., Takaishi, H., Takahashi, T., Fujioka, Y., Takahashi, A., Ishikawa, Y., & Yokoyama, M. (2003) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2003.08.016 · Cited by 53
Docosahexaenoic Acid Is a Major n‐3 Polyunsaturated Fatty Acid in Bovine Retinal Microvessels
Lecomte, M., Paget, C., Ruggiero-Lopez, D., Wiernsperger, N. F., & Lagarde, M. (1996) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1996.66052160.x · Cited by 52
Cyclooxygenase Inhibitors Block Cell Growth, Increase Ceramide and Inhibit Cell Cycle
Kundu, N., Smyth, M. J., Samsel, L., et al. (2002) · Breast Cancer Research and Treatment · doi:10.1023/a:1020224503335 · Cited by 52
Activation of phosphatidylinositol bisphosphate signal transduction pathway after experimental brain injury: a lipid study
Dhillon, H. S., Carbary, T. J., Dose, J. M., Dempsey, R. J., & Prasad, M. R. (1995) · Brain Research · doi:10.1016/0006-8993(95)00840-m · Cited by 52
A study of the composition of fish liver and body oil triglycerides
McGill, A. S., & Moffat, C. F. (1992) · Lipids · doi:10.1007/bf02536151 · Cited by 52
Sterol carrier protein-2 stimulates intermembrane sterol transfer by direct membrane interaction
Woodford, J. K., Colles, S. M., Myers-Payne, S. C., Billheimerb, J. T., & Schroeder, F. (1995) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(95)02436-m · Cited by 51
Lysine deposition responds linearly to marginal lysine intake in Atlantic salmon (Salmo salar L.) parr
Hauler, R. C., & Carter, C. G. (2001) · Aquaculture Research · doi:10.1046/j.1355-557x.2001.00012.x · Cited by 52
Polycyclic aromatic hydrocarbon metabolism in the polychaete Nereis virens
McElroy, A. E. (1990) · Aquatic Toxicology · doi:10.1016/0166-445x(90)90034-m · Cited by 52
Changes in plasma lipoproteins and tissue lipoprotein lipase and salt-resistant lipase activities during spawning in the rainbow trout (salmo gairdnerii r.)
Black, D., & SKINNER, E. R. (1987) · Comparative Biochemistry and Physiology Part B Comparative Biochemistry · doi:10.1016/0305-0491(87)90111-8 · Cited by 52
Influence of fishmeal, rape-seed, and rape-seed meal in feed on the fatty acid composition and storage stability of porcine body fat
Hertzman, C., Göransson, L., & Rudérus, H. (1988) · Meat Science · doi:10.1016/0309-1740(88)90060-5 · Cited by 52
Ornithine‐containing lipids of some Pseudomonas species
KaAWAI, Y., Yano, I., Kaneda, K., et al. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14239.x · Cited by 52
1.alpha.,25,26-Trihydroxyvitamin D3: an in vivo and in vitro metabolite of vitamin D3
Reinhardt, T. A., Napoli, J. L., Praminik, B., et al. (1981) · Biochemistry · doi:10.1021/bi00524a050 · Cited by 52
Characterization of microbial communities in deep groundwater from granitic rock
Jain, D. K., Providenti, M. A., Tanner, C., et al. (1997) · Canadian Journal of Microbiology · doi:10.1139/m97-038 · Cited by 52
Changes in milk carbohydrates during lactation in the common brushtail possum, Trichosurus vulpecula (Marsupialia:Phalangeridae)
Crisp, E., Cowan, P., & Messer, M. (1989) · Reproduction Fertility and Development · doi:10.1071/rd9890309 · Cited by 52
Gramicidin conformational studies with mixed-chain unsaturated phospholipid bilayer systems
Cox, K. J. A., Ho, C., Lombardi, J. V., et al. (1992) · Biochemistry · doi:10.1021/bi00119a020 · Cited by 52
Lipoprotein Lipase (LPL) Strongly Links Native and Oxidized Low Density Lipoprotein Particles to Decorin-coated Collagen
Pentikäinen, M. O., Öörni, K., & Kovanen, P. T. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.8.5694 · Cited by 52
Oxidized LDL Induces an Oxidative Stress and Activates the Tumor Suppressor p53 in MRC5 Human Fibroblasts
Mazière, C., Meignotte, A., Dantin, F., Conte, M.-A., & Mazière, J. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3528 · Cited by 51
Effects of saline stress and calcium on lipid composition in bean roots
Cachorro, P., Antonio, O., & Cerdá, A. (1993) · Phytochemistry · doi:10.1016/s0031-9422(00)95077-5 · Cited by 52
Cholesterol deprivation affects the fluorescence properties of a ceramide analog at the Golgi apparatus of living cells.
Martin, O. C., Comly, M. E., Blanchette‐Mackie, E. J., Pentchev, P. G., & Pagano, R. E. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.7.2661 · Cited by 51
Biochemical markers in feral roach (Rutilus rutilus) in relation to the bioaccumulation of organic trace pollutants
van der Oost, R., van Gastel, L., Worst, D., Hanraads, M., Satumalay, K., van Schooten, F., Heida, H., & Vermeulen, N. P. E. (1994) · Chemosphere · doi:10.1016/0045-6535(94)90048-5 · Cited by 51
Sewage influence in a macrotidal estuary: Fatty acid and sterol distributions
Quéméneur, M., & Marty, Y. (1992) · Estuarine Coastal and Shelf Science · doi:10.1016/s0272-7714(05)80075-7 · Cited by 51
A new approach to the solution of the linear mixing model for a single isotope: application to the case of an opportunistic predator
Hall‐Aspland, S., Hall, A. P., & Rogers, T. L. (2004) · Oecologia · doi:10.1007/s00442-004-1783-0 · Cited by 52
ISOLATION AND CHARACTERIZATION OF LIMA BEAN (PHASEOLUS LUNATUS) STARCH
Hoover, R., Rorke, S., & Martin, A. M. (1991) · Journal of Food Biochemistry · doi:10.1111/j.1745-4514.1991.tb00149.x · Cited by 52
The lethal phenotype caused by null mutations in the Escherichia coli htrB gene is suppressed by mutations in the accBC operon, encoding two subunits of acetyl coenzyme A carboxylase
Karow, M. L., Fayet, O., & Georgopoulos, C. P. (1992) · Journal of Bacteriology · doi:10.1128/jb.174.22.7407-7418.1992 · Cited by 52
PAF-acetylhydrolase activity on Lp(a) before and during Cu2+-induced oxidative modification in vitro
Karabina, S.-A. P., Elisaf, M., Goudevenos, J. A., Siamopoulos, K. C., Sideris, D. A., & Tselepis, A. D. (1996) · Atherosclerosis · doi:10.1016/0021-9150(96)05872-8 · Cited by 53
Temperature-independent and -dependent expression of desaturase genes in filamentous cyanobacterium Spirulina platensis strain C1 (Arthrospira sp. PCC 9438)
Deshnium, P., Paithoonrangsarid, K., Suphatrakul, A., Meesapyodsuk, D., Tanticharoen, M., & Cheevadhanarak, S. (2000) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2000.tb09015.x · Cited by 53
Fatty acid composition of phospholipids in erythrocyte membranes and risk of breast cancer
Zaridze, D. G., Chevchenko, V. E., Levtshuk, A. A., Lifanova, Y., & Maximovitch, D. (1990) · International Journal of Cancer · doi:10.1002/ijc.2910450502 · Cited by 52
Modification of the fatty acid composition of Escherichia coli by coexpression of a plant acyl-acyl carrier protein desaturase and ferredoxin
Cahoon, E. B., Mills, L. A., & Shanklin, J. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.3.936-939.1996 · Cited by 52
Gas vesicle collapse by turgor pressure and its role in buoyancy regulation by Anabaena flos-aquae
Kinsman, R., Ibelings, B. W., & Walsby, A. E. (1991) · Journal of General Microbiology · doi:10.1099/00221287-137-5-1171 · Cited by 52
Transbilayer Movement of Dipalmitoylphosphatidylcholine in Proteoliposomes Reconstituted from Detergent Extracts of Endoplasmic Reticulum
Gummadi, S. N., & Menon, A. K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203809200 · Cited by 52
Increased gap junction assembly between cultured cells upon cholesterol supplementation
Meyer, R. A., Malewicz, B., Baumann, W. J., & Johnson, R. G. (1990) · Journal of Cell Science · doi:10.1242/jcs.96.2.231 · Cited by 52
Diacylglycerol generated in CHO cell plasma membrane by phospholipase C is used for triacylglycerol synthesis
Igal, R. A., Caviglia, J. M., Dumm, I. N. T. D. G., et al. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32339-7 · Cited by 52
Comparison of the lipid regulation of yeast and rat CTP: phosphocholine cytidylyltransferase expressed in COS cells
Johnson, J. E., Kalmar, G. B., SOHAL, P. S., et al. (1992) · Biochemical Journal · doi:10.1042/bj2850815 · Cited by 52
Changes in Lipids of the Salivary Glands of the Lone Star Tick, Amblyomma americanum, during Feeding
Shipley, M. M., Dillwith, J. W., Bowman, A. S., et al. (1993) · Journal of Parasitology · doi:10.2307/3283719 · Cited by 52
Respiratory distress after intratracheal bleomycin: selective deficiency of surfactant proteins B and C
Savani, R. C., Godinez, R. I., Godinez, M. H., et al. (2001) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.2001.281.3.l685 · Cited by 52
Stimulation of phosphatidylcholine breakdown by thrombin and carbachol but not by tyrosine kinase receptor ligands in cells transfected with M1 muscarinic receptors. Rapid desensitization of phosphocholine-specific (PC) phospholipase D but sustained activity of PC-phospholipase C
McKenzie, F. R., Seuwen, K., & Pouysségur, J. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50013-2 · Cited by 52
Lipovitellin from the crustacean, artemia salina. Biochemical analysis of lipovitellin complex from the yolk granules.
de Courcelles, D. D. C., & Kondo, M. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)43632-0 · Cited by 52
Phorbol ester-induced translocation of diacylglycerol kinase from the cytosol to the membrane in Swiss 3T3 fibroblasts
Maroney, A. C., & Macara, I. G. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)81646-0 · Cited by 52
Phospholipids of Thiobacillus thiooxidans
Shively, J., & Benson, A. A. (1967) · Journal of Bacteriology · doi:10.1128/jb.94.5.1679-1683.1967 · Cited by 52
Evidence That the Bradykinin-induced Activation of Phospholipase D and of the Mitogen-activated Protein Kinase Cascade Involve Different Protein Kinase C Isoforms
Clark, K. J., & Murray, A. W. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.13.7097 · Cited by 52
Enhanced immune response to T-independent antigen by using CpG oligodeoxynucleotides encapsulated in liposomes
Li, W. M., Bally, M. B., & Schutze-Redelmeier, M.-P. M. (2001) · Vaccine · doi:10.1016/s0264-410x(01)00277-8 · Cited by 53
The role of different thylakoid glycolipids in the function of reconstituted chloroplast ATP synthase
Pick, U., Weiss, M., Gounaris, K., & Barber, J. (1987) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(87)90080-6 · Cited by 51
Lipid domain structure correlated with membrane protein function in placental microvillus vesicles
Illsley, N. P., Lin, H. Y.-F., & Verkman, A. S. (1987) · Biochemistry · doi:10.1021/bi00376a016 · Cited by 52
Cultured and wild American eels, Anguilla rostrata: Fat content and fatty acid composition
Otwell, W. S., & Rickards, W. L. (1981) · Aquaculture · doi:10.1016/0044-8486(81)90110-1 · Cited by 52
Squamous Carcinoma Cell Lines Produce 1,25 Dihydroxyvitamin D, but Fail to Respond to Its Prodifferentiating Effect
Bikle, D. D., Pillai, S. G., & GEE, E. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12481267 · Cited by 52
Parathyroid hormone inhibition of Na+/phosphate cotransport in OK cells: Generation of second messengers in the regulatory cascade
Quamme, G. A., Pfeilschifter, J. M., & Murer, H. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(89)92814-3 · Cited by 52
Effect of erythrocyte transbilayer phospholipid distribution on fusion with vesicular stomatitis virus
Herrmann, A., Clague, M. J., Puri, A., Morris, S. J., Blumenthal, R., & Grimaldi, S. (1990) · Biochemistry · doi:10.1021/bi00469a005 · Cited by 53
Effects of the Diet on the Composition of Human Milk
Harzer, G., Dieterich, I., & Haug, M. (1984) · Annals of Nutrition and Metabolism · doi:10.1159/000176809 · Cited by 52
Linoleic acid requirement of rats fedtrans fatty acids
Zevenbergen, J. L., Houtsmuller, U. M. T., & Gottenbos, J. J. (1988) · Lipids · doi:10.1007/bf02535455 · Cited by 52
Effect of mercurials on lymphocyte functions in vitro
Nakatsuru, S., Oohashi, J., Nozaki, H., et al. (1985) · Toxicology · doi:10.1016/0300-483x(85)90032-0 · Cited by 52
Retinoylation of the cAMP-binding regulatory subunits of type I and type II cAMP-dependent protein kinases in HL60 cells
Takahashi, N. K., Liapi, C. A., Anderson, W. B., & Breitman, T. R. (1991) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(91)90544-s · Cited by 52
Fatty acid composition and microbial activity of benthic marine sediment from McMurdo Sound, Antarctica
Smith, G. A., Nichols, P. D., & White, D. C. (1986) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1986.tb01732.x · Cited by 52
Evidence for a sex pheromone metabolizing cytochrome P‐450 mono‐oxygenase in the housefly
Ahmad, S., Kirkland, K. E., & Blomquist, G. J. (1987) · Archives of Insect Biochemistry and Physiology · doi:10.1002/arch.940060206 · Cited by 52
R,R,R-α-tocopherol potentiates prostacyclin release in human endothelial cells. Evidence for structural specificity of the tocopherol molecule
Tran, K. T., & Chan, A. C. (1990) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(90)90295-9 · Cited by 52
Acyl and pigment lipid composition of two chlorophyll-proteins
Rawyler, A., Henry, L. E. A., & Siegenthaler, P. (1980) · Carlsberg Research Communications · doi:10.1007/bf02932918 · Cited by 52
Lateral regionalization and diffusion of a maturation-dependent antigen in the ram sperm plasma membrane.
Wolf, D. E., Hagopian, S. S., Lewis, R. G., et al. (1986) · The Journal of Cell Biology · doi:10.1083/jcb.102.5.1826 · Cited by 52
Chemical and Physical Changes in Red Hake Fillets During Frozen Storage
Owusu-Ansah, Y. J., & Hultin, H. O. (1986) · Journal of Food Science · doi:10.1111/j.1365-2621.1986.tb13821.x · Cited by 52
Fat Metabolism in Higher Plants
Newcomb, E. H., & Stumpf, P. K. (1953) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)38455-2 · Cited by 52
Predicting bioaccumulation potential: A test of a fugacity-based model
Ferraro, S. P., Lee, H., Ozretich, R. J., et al. (1990) · Archives of Environmental Contamination and Toxicology · doi:10.1007/bf01054983 · Cited by 52
Crotalocytin: characterization of the timber rattlesnake platelet activating protein
Schmaier, A., & Colman, R. (1980) · Blood · doi:10.1182/blood.v56.6.1020.1020 · Cited by 52

Authors: Bligh, E. G., & Dyer, W. J.
Venue: Canadian Journal of Biochemistry and Physiology
Publisher: Canadian Science Publishing
Published: 1959-08-01
Volume: 37
Issue: 8
Pages: 911-917
ISSN: 0576-5544 (ISSN-L)
DOI: 10.1139/o59-099
OpenAlex: W2152311269
Cited by: 54,751
References: 5
Citations by year: 2026: 1149 · 2025: 1534 · 2024: 1685 · 2023: 1749 · 2022: 1802 · 2021: 2073 · 2020: 2152 · 2019: 1870 · 2018: 1737 · 2017: 1784 · 2016: 1780 · 2015: 1800 · 2014: 1786 · 2013: 1758 · 2012: 1551
FWCI: 8.73
Type: journal article
Language: en
Open access: closed
Licence: www.nrcresearchpress.com/page/about/CorporateTextAndDataMining (tdm)
Locations: Canadian Journal of Biochemistry and Physiology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
Life Sciences › Agricultural and Biological Sciences › Food Science › Food Nutrient Composition and Product Development
Keywords: lipid extraction, lipid purification, chloroform-methanol extraction, frozen fish, lipid degradation, fish muscle, tissue homogenization, rapid extraction method
MeSH terms: Fishes, Lipids

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks