Mechanism of oxidation of tetrahydropterins

Pterin-Dependent Amino Acid Hydroxylases

Kappock, T. J., & Caradonna, J. P. (1996) · Chemical Reviews · doi:10.1021/cr9402034 · Cited by 325 · see citing works

The Role of Iron Regulation in Immunometabolism and Immune-Related Disease

Cronin, S. J. F., Woolf, C. J., Weiss, G., & Penninger, J. M. (2019) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2019.00116 · Cited by 299 · see citing works

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

Cronin, S. J. F., Seehus, C., Weidinger, A., Talbot, S., Reissig, S., Seifert, M., Pierson, Y., McNeill, E., Longhi, M. S., Turnes, B. L., et al. (2018) · Nature · doi:10.1038/s41586-018-0701-2 · Cited by 285 · see citing works

N EW P ERSPECTIVES ON F OLATE C ATABOLISM

Suh, J. R., Herbig, A. K., & Stover, P. J. (2001) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.21.1.255 · Cited by 261 · see citing works

Tetrahydrobiopterin Radical Enzymology

Wei, C.-C., Crane, B. R., & Stuehr, D. J. (2003) · Chemical Reviews · doi:10.1021/cr0204350 · Cited by 175 · see citing works

Tetrahydrobiopterin, a cofactor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine.

Giovanelli, J., Campos, K. L., & Kaufman, S. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.7091 · Cited by 162 · see citing works

Structural characterization of a molybdopterin precursor

Wuebbens, M. M., & Rajagopalan, K. V. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38676-4 · Cited by 118 · see citing works

Reaction of tetrahydrobiopterin with superoxide: EPR-kinetic analysis and characterization of the pteridine radical

Vásquez-Vivar, J., Whitsett, J., Martásek, P., Hogg, N., & Kalyanaraman, B. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00680-3 · Cited by 112 · see citing works

Purification and Properties of a Folate-catabolizing Enzyme

Suh, J. R., Oppenheim, E. W., Girgis, S., & Stover, P. J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m005864200 · Cited by 79 · see citing works

Dihydrofolate Reductase: Binding of Substrates and Inhibitors and Catalytic Mechanism

Gready, J. E. (1980) · Advances in pharmacology · doi:10.1016/s1054-3589(08)60007-1 · Cited by 50 · see citing works

Characteristics of the Nitric Oxide Synthase-catalyzed Conversion of Arginine to N-Hydroxyarginine, the First Oxygenation Step in the Enzymic Synthesis of Nitric Oxide

Campos, K. L., Giovanelli, J., & Kaufman, S. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.4.1721 · Cited by 49 · see citing works

Dihydropteridine reductase (DHPR), its cofactors, and its mode of action

Armarego, W. L. F., Randles, D., & Waring, P. (1984) · Medicinal Research Reviews · doi:10.1002/med.2610040302 · Cited by 45 · see citing works

The state of reduction of molybdopterin in xanthine oxidase and sulfite oxidase.

Gardlik, S., & Rajagopalan, K. V. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38265-1 · Cited by 39 · see citing works

Tetrahydrobiopterin rapidly reduces the SOD mimic Mn(III) ortho-tetrakis(N-ethylpyridinium-2-yl)porphyrin

Batinic̈‐Haberle, I., Spasojević, I., & Fridovich, I. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.04.041 · Cited by 38 · see citing works

Redox Properties of Human Endothelial Nitric-oxide Synthase Oxygenase and Reductase Domains Purified from Yeast Expression System

Du, M., Yeh, H.-C., Berka, V., Wang, L.-H., & Tsai, A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209606200 · Cited by 37 · see citing works

Oxidation of molybdopterin in sulfite oxidase by ferricyanide. Effect on electron transfer activities.

Gardlik, S., & Rajagopalan, K. V. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)67732-x · Cited by 36 · see citing works

Formation of Oxygen Radicals in Solutions of 7,8-Dihydroneopterin

Oettl, K., Wirleitner, B., Baier-Bitterlich, G., Grammer, T. B., Fuchs, D., & Reibnegger, G. J. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1520 · Cited by 34 · see citing works

Molybdopterin Radical in Bacterial Aldehyde Dehydrogenases

Luykx, D. M. A. M., Duine, J. A., & de Vries, S. (1998) · Biochemistry · doi:10.1021/bi972972y · Cited by 28 · see citing works

The relative stabilities of dihydropterins; a comment on the structure of Moco, the cofactor of the oxomolybdoenzymes

Greatbanks, S. P., Hillier, I. H., Garner, C. D., & JOULE, J. A. (1997) · Journal of the Chemical Society Perkin Transactions 2 · doi:10.1039/a700330g · Cited by 26 · see citing works

The Effect of Substrate, Dihydrobiopterin, and Dopamine on the EPR Spectroscopic Properties and the Midpoint Potential of the Catalytic Iron in Recombinant Human Phenylalanine Hydroxylase

Hagedoorn, P., Schmidt, P. P., Andersson, K. K., Hagen, W. R., Flatmark, T., & Martı́nez, A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009458200 · Cited by 25 · see citing works

Properties of Xanthine Dehydrogenase Variants from Rosy Mutant Strains of Drosophila melanogaster and their Relevance to the enzyme's Structure and Mechanism

Doyle, W. A., Burke, J. F., Chovnick, A., Dutton, F. L., Whittle, J. R. S., & Bray, R. C. (1996) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1996.0782u.x · Cited by 25 · see citing works

Isolation and characterization of quinonoid dihydropterins by high-performance liquid chromatography

Haavik, J., & Flatmark, T. (1983) · Journal of Chromatography A · doi:10.1016/s0021-9673(01)88192-9 · Cited by 19 · see citing works

Reduction of ferric haemoproteins by tetrahydropterins: a kinetic study

Capeillère‐Blandin, C., Mathieu, D., & Mansuy, D. (2005) · Biochemical Journal · doi:10.1042/bj20050437 · Cited by 17 · see citing works

H2O2‐mediated oxidation of tetrahydrobiopterin: Fourier transform Raman investigations provide mechanistic implications for the enzymatic utilization and recycling of this essential cofactor

Moore, J., Wood, J. M., & Schallreuter, K. U. (2002) · Journal of Raman Spectroscopy · doi:10.1002/jrs.887 · Cited by 16 · see citing works

Reactions of CO 2 ˙ – radicals with pterin and pterin-6-carboxylate ions

Farahani, M., Surdhar, P. S., Allen, S., Armstrong, D. A., Schöneich, C., Mao, Y., & Asmus, K. (1991) · Journal of the Chemical Society Perkin Transactions 2 · doi:10.1039/p29910001687 · Cited by 14 · see citing works

474—Electrochemistry of 6,7-dimethylpterins

Ege-Serpkenci, D., & Dryhurst, G. (1982) · Bioelectrochemistry and Bioenergetics · doi:10.1016/0302-4598(82)80174-8 · Cited by 14 · see citing works

Optimised extraction of folic acid from multivitamin-mineral preparations for liquid chromatographic analysis

Kall, M. A., Nørgaard, P., Pedersen, S. J., & Leth, T. (2000) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/s0731-7085(00)00327-7 · Cited by 13 · see citing works

New pteridine substrates for dihydropteridine reductase and horseradish peroxidase

Armarego, W. L. F., Ohnishi, A., & Taguchi, H. (1986) · Biochemical Journal · doi:10.1042/bj2340335 · Cited by 12 · see citing works

Study of the tautomerization of quinonoid dihydropterins by liquid chromatography/electrochemistry

Lunte, C. E., & Kissinger, P. T. (1984) · Analytica Chimica Acta · doi:10.1016/s0003-2670(00)84811-4 · Cited by 10 · see citing works

Quinonoid dihydrobiopterin, an important metabolic intermediate of biopterin cofactor in the aromatic hydroxylation of amino acids

Matsuura, S., Murata, S., & Sugimoto, T. (1986) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)84047-2 · Cited by 10 · see citing works

Pteridine, LX. Synthese und Oxidationsverhalten von 7,8‐Dihydroxanthopterinen

Pfleiderer, W. (1974) · Chemische Berichte · doi:10.1002/cber.19741070305 · Cited by 10 · see citing works

Complex Formation and Redox Reactions in Copper–Pterin Cofactor Systems. Possible Relevance to Phenylalanine Hydroxylase

Funahashi, Y., Kato, C., & Yamauchi, O. (1999) · Bulletin of the Chemical Society of Japan · doi:10.1246/bcsj.72.415 · Cited by 9 · see citing works

Investigation of 6-methylpterin electrochemistry by dual-electrode liquid chromatography/electrochemistry

Lunte, C. E., & Kissinger, P. T. (1984) · Analytical Chemistry · doi:10.1021/ac00268a016 · Cited by 9 · see citing works

Synthesis, Redox and Spectroscopic Properties of Pterin of Molybdenum Cofactors

Colston, K. J., & Basu, P. (2022) · Molecules · doi:10.3390/molecules27103324 · Cited by 7 · see citing works

Quantification of Monoamine Neurotransmitter Metabolites and Cofactors in Cerebrospinal Fluid: State-of-the-Art

Boulghobra, A., & Bonose, M. (2022) · Critical Reviews in Analytical Chemistry · doi:10.1080/10408347.2022.2151833 · Cited by 6 · see citing works

Autoxidation Kinetics of Tetrahydrobiopterin—Giving Quinonoid Dihydrobiopterin the Consideration It Deserves

Boulghobra, A., Bonose, M., Alhajji, E., Pallandre, A., Roze, E. F., Baudin, B., Menet, M., & Moussa, F. (2023) · Molecules · doi:10.3390/molecules28031267 · Cited by 5 · see citing works

Generation of carbon monoxide and iron from hemeproteins in the presence of 7,8-dihydroneopterin

Horejsi, R., Jung, C., Möller, R., Tafeit, E., & Reibnegger, G. J. (2002) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(02)00206-4 · Cited by 5 · see citing works

Biosynthesis and Function of Unconjugated Pterins in Mammalian Tissues

Gal, E. M. (1982) · Springer eBooks · doi:10.1007/978-1-4684-7541-8_2 · Cited by 5 · see citing works

A Comprehensive Computational Study on the Thermodynamics and Kinetics of Tetrahydrobiopterin Regeneration Process

Samanta, S., & Mondal, P. (2024) · ChemPhysChem · doi:10.1002/cphc.202400401 · Cited by 1 · see citing works

Neopterin, Dihydroneopterin, Tetrahydroneopterin: Different Structures-Increasing Capacity Cleaving the Porphyrin in Heme Proteins

Horejsi, R., Möller, R., Tafeit, E., & Reibnegger, G. J. (2002) · Pteridines · doi:10.1515/pteridines.2002.13.4.115 · Cited by 1 · see citing works

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Faculty Opinions recommendation of The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

Ichinose, M., & Yamada, M. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734378603.793555631

Faculty Opinions recommendation of The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

Chandel, N. S. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734378603.793554283

Hunt for NDSRIs: Unveiling Hidden Threats with the Novel 15 N-Enriched NAP Test

Simonetto, A., Monzani, E., Razzetti, G., & Mantegazza, S. (2025) · Organic Process Research & Development · doi:10.1021/acs.oprd.5c00223

Chemical and biological dynamics of natural pterins

Doi, Y. (2026) · Bioscience Biotechnology and Biochemistry · doi:10.1093/bbb/zbag094

Oxidation of methylated tetrahydropterins

Ege-Serpkenci, D., Raghavan, R., & Dryhurst, G. (1983) · Journal of Electroanalytical Chemistry · doi:10.1016/s0022-0728(83)80496-3

Electrochemistry of Reduced Pterin Cofactors

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Pterins. Part 9. The structure of quinonoid dihydropterins [2-amino-7,8-dihydropteridin-4(6H)-ones]

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Electrochemical oxidation of 5-methyl-5,6,7,8-tetrahydropterin

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Redox chemistry of reduced pterin species

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