Cited by 2Advanced Database Systems and QueriesNatural Language Processing TechniquesSoftware System Performance and Reliability

Efficient LLM Serving for Agentic Workflows: A Data Systems Perspective

Open access
Wadlom, Noppanat, Shen, Junyi, Lu, Yao·2026·Proceedings of the ACM on Management of Data

Abstract

Agentic workflows are composed of sequences of interdependent Large Language Model (LLM) calls, and they have become a dominant workload in modern AI systems. These workflows exhibit extensive redundancy from overlapping prompts and intermediate results due to speculative and parallel exploration. Existing LLM serving systems, such as vLLM, focus on optimizing individual inference calls and overlook cross-call dependencies, leading to significant inefficiencies. This paper rethinks LLM and agent serving from a data systems perspective and introduces Helium, a workflow-aware serving framework that models agentic workloads as query plans and treats LLM invocations as first-class operators. Helium integrates proactive caching and cache-aware scheduling to maximize reuse across prompts, KV states, and workflows. Through these techniques, Helium bridges classic query optimization principles with LLM serving, achieving up to 1.56× speedup over state-of-the-art agent serving systems on various workloads. Our results demonstrate that end-to-end optimization across workflows is essential for scalable and efficient LLM-based agents.

Integrity signals

Registry

Crossref · 10.1145/3802046

Cites

15 of 15 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Wadlom, N., Shen, J., & Lu, Y.
Affiliations
National University of Singapore (SG)
Venue
Proceedings of the ACM on Management of Data
Published
2026-05-18
Volume
4
Issue
3
Pages
1-29
ISSN
2836-6573 (ISSN-L)
OpenAlex
W7161545122
Cited by
0
References
15
FWCI
0.00
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
Proceedings of the ACM on Management of Data (publishedVersion, cc-by)
Topics
  • Physical Sciences › Computer Science › Computer Networks and Communications › Advanced Database Systems and Queries
  • Physical Sciences › Computer Science › Artificial Intelligence › Natural Language Processing Techniques
  • Physical Sciences › Computer Science › Computer Networks and Communications › Software System Performance and Reliability
Keywords
large language model inference, agentic workflows, large language models, helium, proactive caching, cache-aware scheduling, query optimization, LLM agents, vLLM

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review