The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Electrochemical Analysis of Neurotransmitters
Open accessAbstract
Chemical signaling through the release of neurotransmitters into the extracellular space is the primary means of communication between neurons. More than four decades ago, Ralph Adams and his colleagues realized the utility of electrochemical methods for the study of easily oxidizable neurotransmitters, such as dopamine, norepinephrine, and serotonin and their metabolites. Today, electrochemical techniques are frequently coupled to microelectrodes to enable spatially resolved recordings of rapid neurotransmitter dynamics in a variety of biological preparations spanning from single cells to the intact brain of behaving animals. In this review, we provide a basic overview of the principles underlying constant-potential amperometry and fast-scan cyclic voltammetry, the most commonly employed electrochemical techniques, and the general application of these methods to the study of neurotransmission. We thereafter discuss several recent developments in sensor design and experimental methodology that are challenging the current limitations defining the application of electrochemical methods to neurotransmitter measurements.
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Cites
Addiction is a Reward Deficit and Stress Surfeit Disorder
Koob, G. F. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00072 · Cited by 397
In-Vivo Electrochemistry: What Can We Learn about Living Systems?
Wilson, G. S., & Johnson, M. A. (2008) · Chemical Reviews · doi:10.1021/cr068082i · Cited by 178
Systematic analysis of neural projections reveals clonal composition of the Drosophila brain
Ito, M., Masuda, N., Shinomiya, K., Endo, K., & Ito, K. (2013) · Current Biology · doi:10.1016/j.cub.2013.03.015 · Cited by 166
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Self-citationOwesson‐White, C. A., Ariansen, J., Stuber, G. D., Cleaveland, N. A., Cheer, J. F., Mark Wightman, R., & Carelli, R. M. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06916.x · Cited by 126
Deep brain stimulation induces striatal dopamine release in obsessive-compulsive disorder
Figee, M., de Koning, P., Klaassen, S., Vulink, N., Mantione, M., van den Munckhof, P., Schuurman, R., van Wingen, G., van Amelsvoort, T., Booij, J., et al. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.06.021 · Cited by 112
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Fundamentals of fast-scan cyclic voltammetry for dopamine detection
Venton, B. J., & Cao, Q. (2020) · The Analyst · doi:10.1039/c9an01586h · Cited by 357
Employing Conductive Metal–Organic Frameworks for Voltammetric Detection of Neurochemicals
Ko, M., Mendecki, L., Eagleton, A. M., Durbin, C. G., Stolz, R. M., Meng, Z., & Mirica, K. A. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.9b13402 · Cited by 298
Recent advances in neurotechnologies with broad potential for neuroscience research
Vázquez-Guardado, A., Yang, Y., Bandodkar, A. J., & Rogers, J. A. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-00739-8 · Cited by 202
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Metadata
- Authors
- Bucher, E. S., & Wightman, R. M.
- Venue
- Annual Review of Analytical Chemistry
- Publisher
- Annual Reviews
- Published
- 2015-07-22
- Volume
- 8
- Issue
- 1
- Pages
- 239-261
- ISSN
- 1936-1327 (ISSN-L)
- 1936-1335
- OpenAlex
- W2157425349
- Cited by
- 298
- References
- 6
- FWCI
- 2.53
- Type
- journal article
- Language
- en
- Open access
- green
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