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Cited by 290

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.

Mechanism and Regulation of Centriole and Cilium Biogenesis

Open access
Breslow, David K., Holland, Andrew J.·2019·Annual Review of Biochemistry

Abstract

The centriole is an ancient microtubule-based organelle with a conserved nine-fold symmetry. Centrioles form the core of centrosomes, which organize the interphase microtubule cytoskeleton of most animal cells and form the poles of the mitotic spindle. Centrioles can also be modified to form basal bodies, which template the formation of cilia and play central roles in cellular signaling, fluid movement, and locomotion. In this review, we discuss developments in our understanding of the biogenesis of centrioles and cilia and the regulatory controls that govern their structure and number. We also discuss how defects in these processes contribute to a spectrum of human diseases and how new technologies have expanded our understanding of centriole and cilium biology, revealing exciting avenues for future exploration.

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Crossref · 10.1146/annurev-biochem-013118-111153

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Metadata

Authors
Breslow, D. K., & Holland, A. J.
Venue
Annual Review of Biochemistry
Published
2019-06-20
Volume
88
Issue
1
Pages
691-724
ISSN
  • 0066-4154 (ISSN-L)
  • 1545-4509
OpenAlex
W2908004295
Cited by
290
References
26
FWCI
4.03
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Mechanism and Regulation of Centriole and Cilium Biogenesis. https://app.cochat.ai/papers/10.1146/annurev-biochem-013118-111153
The paper
Breslow, D. K., & Holland, A. J. (2019). Mechanism and Regulation of Centriole and Cilium Biogenesis. Annual Review of Biochemistry. https://doi.org/10.1146/annurev-biochem-013118-111153

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.