The DOI matches its Crossref record; 137 of the 137 references it cites were found in a registry or an index.
Regulation of Integrin Activation
Abstract
Regulation of cell-cell and cell-matrix interaction is essential for the normal physiology of metazoans and is important in many diseases. Integrin adhesion receptors can rapidly increase their affinity (integrin activation) in response to intracellular signaling events in a process termed inside-out signaling. The transmembrane domains of integrins and their interactions with the membrane are important in inside-out signaling. Moreover, integrin activation is tightly regulated by a complex network of signaling pathways. Here, we review recent progress in understanding how the membrane environment can, in cooperation with integrin-binding proteins, regulate integrin activation.
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Crystal Structure of the Extracellular Segment of Integrin αVβ3
Xiong, J.-P., Stehle, T., Diefenbach, B., Zhang, R., Dunker, R., Scott, D. L., Joachimiak, A., Goodman, S. L., & Arnaout, M. A. (2001) · Science · doi:10.1126/science.1064535 · Cited by 1,276
Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation
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Self-citationTakagi, J., Petre, B. M., Walz, T., & Springer, T. A. (2002) · Cell · doi:10.1016/s0092-8674(02)00935-2 · Cited by 1,168
Platelet-collagen interaction: is GPVI the central receptor?
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The final steps of integrin activation: the end game
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Self-citation
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Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow
Wang, L., Luo, J.-Y., Li, B., Tian, X. Y., Chen, L.-J., Huang, Y., Liu, J., Deng, D., Lau, C. W., Wan, S., et al. (2016) · Nature · doi:10.1038/nature20602 · Cited by 668
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McEver, R. P. (2015) · Cardiovascular Research · doi:10.1093/cvr/cvv154 · Cited by 575
Integrin activation by talin, kindlin and mechanical forces
Sun, Z., Costell, M., & Fässler, R. (2019) · Nature Cell Biology · doi:10.1038/s41556-018-0234-9 · Cited by 543
Chen, X., Wanggou, S., Bodalia, A., Zhu, M., Dong, W., Fan, J. J., Yin, W. C., Min, H.-K., Hu, M., Draghici, D., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.09.046 · Cited by 401
The role of integrins in inflammation and angiogenesis
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Metadata
- Authors
- Kim, C., Ye, F., & Ginsberg, M. H.
- Venue
- Annual Review of Cell and Developmental Biology
- Publisher
- Annual Reviews
- Published
- 2011-11-10
- Volume
- 27
- Issue
- 1
- Pages
- 321-345
- ISSN
- 1081-0706 (ISSN-L)
- 1530-8995
- OpenAlex
- W2135577930
- Cited by
- 437
- References
- 137
- FWCI
- 3.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kim, C., Ye, F., & Ginsberg, M. H. (2011). Regulation of Integrin Activation. Annual Review of Cell and Developmental Biology. https://doi.org/10.1146/annurev-cellbio-100109-104104
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
