Cytoplasmic Mechanisms of Recognition and Defense of Microbial Nucleic Acids

Pathogen Recognition and Innate Immunity

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

Kawai, T., & Akira, S. (2010) · Nature Immunology · doi:10.1038/ni.1863 · Cited by 9,304

Pattern Recognition Receptors and Inflammation

Takeuchi, O., & Akira, S. (2010) · Cell · doi:10.1016/j.cell.2010.01.022 · Cited by 8,895

A Toll-like receptor recognizes bacterial DNA

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Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Sun, L., Wu, J., Du, F., Chen, X., & Chen, Z. J. (2013) · Science · doi:10.1126/science.1232458 · Cited by 4,996

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

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Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

Kawai, T., & Akira, S. (2011) · Immunity · doi:10.1016/j.immuni.2011.05.006 · Cited by 3,658

Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

Kasravi, M., Ahmadi, A., Babajani, A., Mazloomnejad, R., Hatamnejad, M. R., Shariatzadeh, S., Bahrami, S., & Niknejad, H. (2023) · Biomaterials Research · doi:10.1186/s40824-023-00348-z · Cited by 316

Cytosolic DNA sensing by cGAS: regulation, function, and human diseases

Yu, L., & Liu, P. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00554-y · Cited by 295

Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation

Platanitis, E., & Decker, T. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02542 · Cited by 263

Mitochondrial DNA-triggered innate immune response: mechanisms and diseases

Hu, M.-M., & Shu, H. (2023) · Cellular and Molecular Immunology · doi:10.1038/s41423-023-01086-x · Cited by 263

SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response

Fu, Y.-Z., Wang, S., Zheng, Z.-Q., Huang, Y., Li, W.-W., Xu, Z.-S., & Wang, Y. (2020) · Cellular and Molecular Immunology · doi:10.1038/s41423-020-00571-x · Cited by 219

Innate Immune Response to Cytoplasmic DNA: Mechanisms and Diseases

Hu, M., & Shu, H. (2019) · Annual Review of Immunology · doi:10.1146/annurev-immunol-070119-115052 · Cited by 160

Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis

Zhong, L., Hu, M., Bian, L., Liu, Y., Chen, Q., & Shu, H. (2020) · Cell Discovery · doi:10.1038/s41421-020-0162-2 · Cited by 139

The Membrane-Associated MARCH E3 Ligase Family: Emerging Roles in Immune Regulation

Lin, H., Li, S., & Shu, H.-B. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01751 · Cited by 124

DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity

Sun, X., Liu, T., Zhao, J., Xia, H., Xie, J., Guo, Y., Zhong, L., Li, M., Yang, Q., Peng, C., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-19941-0 · Cited by 129

Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity

Hu, M., He, W.-R., Gao, P., Yang, Q., He, K. F., Cao, L.-B., Li, S., Feng, Y., & Shu, H. (2019) · Cell Research · doi:10.1038/s41422-018-0136-1 · Cited by 121

KAT5 acetylates cGAS to promote innate immune response to DNA virus

Song, Z.-M., Lin, H., Yi, X.-M., Guo, W., Hu, M., & Shu, H. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1922330117 · Cited by 109

An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity

Schmidt, N., Domingues, P., Gołębiowski, F., Patzina, C., Tatham, M. H., Hay, R. T., & Hale, B. G. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1907031116 · Cited by 113

African swine fever virus I267L acts as an important virulence factor by inhibiting RNA polymerase III-RIG-I-mediated innate immunity

Ran, Y., Li, D., Xiong, M.-G., Liu, H., Feng, T., Shi, Z., Li, Y., Wu, H.-N., Wang, S., Zheng, H., et al. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010270 · Cited by 91

RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA

Zhang, Z.-D., Xiong, T.-C., Yao, S., Wei, M., Chen, M., Lin, D., & Zhong, B. (2020) · Nature Communications · doi:10.1038/s41467-020-19318-3 · Cited by 87

PTPN1/2-mediated dephosphorylation of MITA/STING promotes its 20S proteasomal degradation and attenuates innate antiviral response

Xia, T., Yi, X.-M., Wu, X., Shang, J., & Shu, H. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1906431116 · Cited by 83

USP29 maintains the stability of cGAS and promotes cellular antiviral responses and autoimmunity

Zhang, Q., Tang, Z., An, R., Ye, L., & Zhong, B. (2020) · Cell Research · doi:10.1038/s41422-020-0341-6 · Cited by 86

RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation

Yang, B., Liu, Y., Cui, Y., Song, D., Zhang, G., Ma, S., Liu, Y., Chen, M., Chen, F., Wang, H., et al. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008387 · Cited by 78

NS1: A Key Protein in the “Game” Between Influenza A Virus and Host in Innate Immunity

Ji, Z., Wang, X., & Liu, X. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.670177 · Cited by 82

Pattern recognition receptor‐mediated inflammation in diabetic vascular complications

Wang, X., Antony, V., Wang, Y., Wu, G., & Liang, G. (2020) · Medicinal Research Reviews · doi:10.1002/med.21711 · Cited by 73

MAVS integrates glucose metabolism and RIG-I-like receptor signaling

He, Q.-Q., Huang, Y., Nie, L., Ren, S., Xu, G., Deng, F., Cheng, Z., Zuo, Q., Zhang, L., Cai, H., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-41028-9 · Cited by 65

Deciphering the pathways to antiviral innate immunity and inflammation

Yang, Q., & Shu, H. (2019) · Advances in immunology · doi:10.1016/bs.ai.2019.11.001 · Cited by 66

cGAS/STING signalling pathway in senescence and oncogenesis

Yu, L., & Liu, P. (2024) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2024.08.007 · Cited by 67

PCBP1 modulates the innate immune response by facilitating the binding of cGAS to DNA

Liao, C.-Y., Lei, C., & Shu, H. (2020) · Cellular and Molecular Immunology · doi:10.1038/s41423-020-0462-3 · Cited by 58

VRK2 is involved in the innate antiviral response by promoting mitostress-induced mtDNA release

He, W.-R., Cao, L.-B., Yang, Y.-L., Hua, D., Hu, M., & Shu, H. (2021) · Cellular and Molecular Immunology · doi:10.1038/s41423-021-00673-0 · Cited by 62

Human cytomegalovirus protein UL42 antagonizes cGAS/MITA-mediated innate antiviral response

Fu, Y.-Z., Guo, Y., Zou, H.-M., Su, S., Wang, S., Yang, Q., Luo, M., & Wang, Y. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1007691 · Cited by 60

USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA

Ye, L., Zhang, Q., Liuyu, T., Xu, Z., Zhang, M., Luo, M., Zeng, W., Zhu, Q., Lin, D., & Zhong, B. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1007680 · Cited by 53

Dephosphorylation of cGAS by PPP6C impairs its substrate binding activity and innate antiviral response

Li, M., & Shu, H. (2020) · Protein & Cell · doi:10.1007/s13238-020-00729-3 · Cited by 50

The monkeypox virus-host interplays

Yi, X.-M., Lei, Y., Li, M., Zhong, L., & Li, S. (2024) · Cell Insight · doi:10.1016/j.cellin.2024.100185 · Cited by 47

Regulation and function of the cGAS-MITA/STING axis in health and disease

Zhang, Z.-D., & Zhong, B. (2022) · Cell Insight · doi:10.1016/j.cellin.2021.100001 · Cited by 44

Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone

Su, S., Hua, D., Li, J.-P., Zhang, X., Bai, L., Cao, L.-B., Guo, Y., Zhang, M., Dong, J., Liang, X.-W., et al. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-00981-5 · Cited by 41

Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair

Aditi, A., Downing, S. M., Schreiner, P. A., Kwak, Y. D., Li, Y., Shaw, T. I., Russell, H. R., & McKinnon, P. J. (2021) · Neuron · doi:10.1016/j.neuron.2021.09.040 · Cited by 42

USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA

Zhang, H., Liao, B.-W., Xu, Z.-S., Ran, Y., Wang, D., Yang, Y., Luo, W., & Wang, Y. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008178 · Cited by 39

USP20 Promotes Cellular Antiviral Responses via Deconjugating K48-Linked Ubiquitination of MITA

Zhang, M., Cai, Z., Zhang, M., Wang, X., Wang, Y., Zhao, F., Zhu, Q., Luo, M., Zhu, Q., Xu, Z., et al. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1801447 · Cited by 33

Evasion of host defense by Brucella

Yang, J., Wang, Y., Hou, Y., Sun, M., Xia, T., & Wu, X. G. (2023) · Cell Insight · doi:10.1016/j.cellin.2023.100143 · Cited by 33

Human Cytomegalovirus DNA Polymerase Subunit UL44 Antagonizes Antiviral Immune Responses by Suppressing IRF3- and NF-κB-Mediated Transcription

Fu, Y.-Z., Su, S., Zou, H.-M., Guo, Y., Wang, S., Li, S., Luo, M., & Wang, Y. (2019) · Journal of Virology · doi:10.1128/jvi.00181-19 · Cited by 33

SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA

Guo, W., Wei, J., Zhong, X., Zang, R., Lian, H., Hu, M., Li, S., Shu, H., & Yang, Q. (2019) · Cellular and Molecular Immunology · doi:10.1038/s41423-019-0285-2 · Cited by 33

Modulation of Host Antiviral Innate Immunity by African Swine Fever Virus: A Review

He, W.-R., Yuan, J., Ma, Y., Zhao, C.-Y., Yang, Z., Zhang, Y., Han, S., Wan, B., & Zhang, G. (2022) · Animals · doi:10.3390/ani12212935 · Cited by 32

Efficient Dicer processing of virus-derived double-stranded RNAs and its modulation by RIG-I-like receptor LGP2

Zhang, Y., Xu, Y., Dai, Y., Li, Z., Wang, J., Ye, Z., Ren, Y., Wang, H., Li, W.-X., Lü, J., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009790 · Cited by 31

Mouse circulating extracellular vesicles contain virus‐derived siRNAs active in antiviral immunity

Zhang, Y., Dai, Y., Wang, J., Xu, Y., Li, Z., Lü, J., Xu, Y., Zhong, J., Ding, S., & Li, Y. (2022) · The EMBO Journal · doi:10.15252/embj.2021109902 · Cited by 31

Aquatic animal viruses mediated immune evasion in their host

Ke, F., & Zhang, Q.-Y. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.12.027 · Cited by 30

Opposing effects of deubiquitinase OTUD3 in innate immunity against RNA and DNA viruses

Cai, X., Zhou, Z., Zhu, J., Liu, X., Ouyang, G., Wang, J., Li, Z., Li, X., Zha, H., Zhu, C., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110920 · Cited by 30

Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease

Song, J., Yang, R., Chang, J., Liu, Y., Lu, C.-H., Chen, L., Guo, H., Zhang, Y., Fan, Z., Zhou, J., et al. (2022) · Acta Pharmacologica Sinica · doi:10.1038/s41401-022-01002-5 · Cited by 30

Cellular uptake of extracellular nucleosomes induces innate immune responses by binding and activating cGMP-AMP synthase (cGAS)

Wang, H., Zang, C., Ren, M., Shang, M., Wang, Z., Peng, X., Zhang, Q., Wen, X., Xi, Z., & Zhou, C. (2020) · Scientific Reports · doi:10.1038/s41598-020-72393-w · Cited by 29

The molecular mechanisms of extracellular matrix-derived hydrogel therapy in idiopathic pulmonary fibrosis models

Evangelista-Leite, D., Carreira, A. C. O., Nishiyama, M. Y., Gilpin, S. E., & Miglino, M. A. (2023) · Biomaterials · doi:10.1016/j.biomaterials.2023.122338 · Cited by 27

Herpes simplex virus protein UL56 inhibits cGAS-Mediated DNA sensing to evade antiviral immunity

Zheng, Z.-Q., Fu, Y.-Z., Wang, S., Xu, Z.-S., Zou, H.-M., & Wang, Y. (2022) · Cell Insight · doi:10.1016/j.cellin.2022.100014 · Cited by 25

Multimericity Amplifies the Synergy of BCR and TLR4 for B Cell Activation and Antibody Class Switching

Pone, E. J., Hernandez‐Davies, J. E., Jan, S., Silzel, E. K., Felgner, P. L., & Davies, D. H. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.882502 · Cited by 29

Endocytosis triggers V-ATPase-SYK–mediated priming of cGAS activation and innate immune response

Yang, Y.-L., Cao, L.-B., He, W.-R., Zhong, L., Guo, Y., Yang, Q., Shu, H., & Hu, M. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2207280119 · Cited by 25

Lactiplantibacillus plantarum Strains Modulate Intestinal Innate Immune Response and Increase Resistance to Enterotoxigenic Escherichia coli Infection

Baillo, A. A., Villena, J., Albarracín, L., Tomokiyo, M., Elean, M., Fukuyama, K., Quilodrán-Vega, S., Fadda, S., & Kitazawa, H. (2022) · Microorganisms · doi:10.3390/microorganisms11010063 · Cited by 24

ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response

Zhong, X., Feng, L., Zang, R., Lei, C., Yang, Q., & Shu, H. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008457 · Cited by 24

Chikungunya Virus Vaccines: Platforms, Progress, and Challenges

DeFilippis, V. R. (2019) · Current topics in microbiology and immunology · doi:10.1007/82_2019_175 · Cited by 24

The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response

Li, C., Feng, L., Luo, W., Lei, C., Li, M., & Shu, H. (2021) · Cell Discovery · doi:10.1038/s41421-021-00277-y · Cited by 27

TRAF7 negatively regulates the RLR signaling pathway by facilitating the K48-linked ubiquitination of TBK1

Huang, J., Yang, Y., Chen, T., Wang, D., Li, J., & Xu, L. (2023) · Virologica Sinica · doi:10.1016/j.virs.2023.04.005 · Cited by 18

Estrogen receptor α-mediated signaling inhibits type I interferon response to promote breast carcinogenesis

Cao, L.-B., Ruan, Z.-L., Yang, Y.-L., Zhang, N.-C., Gao, C., Cai, C., Zhang, J., Hu, M.-M., & Shu, H. (2023) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjad047 · Cited by 18

The Contribution of Viral Proteins to the Synergy of Influenza and Bacterial Co-Infection

Mikušová, M., Tomčíková, K., Briestenská, K., Kostolanský, F., & Varečková, E. (2022) · Viruses · doi:10.3390/v14051064 · Cited by 19

β-adrenoreceptor-triggered PKA activation negatively regulates the innate antiviral response

Guo, Y., Zhang, X., Su, S., Ruan, Z.-L., Hu, M., & Shu, H. (2023) · Cellular and Molecular Immunology · doi:10.1038/s41423-022-00967-x · Cited by 16

CSK promotes innate immune response to DNA virus by phosphorylating MITA

Gao, P., Hu, M., & Shu, H. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.03.069 · Cited by 16

Post-Translational Modifications of Proteins in Cytosolic Nucleic Acid Sensing Signaling Pathways

Deng, Y. L., Wang, Y., Li, L., Miao, E. A., & Liu, P. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.898724 · Cited by 16

Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition

Liu, Y., Abula, A., Xiao, H., Guo, H., Li, T., Zheng, L., Chen, B., Nguyen, H. C., & Ji, X. (2022) · Journal of Molecular Biology · doi:10.1016/j.jmb.2022.167920 · Cited by 15

Vaccinia virus subverts xenophagy through phosphorylation and nuclear targeting of p62

Krause, M., Samolej, J., Yakimovich, A., Kriston-Vizi, J., Huttunen, M., Reyna, S. J. L., Frickel, E., & Mercer, J. (2024) · The Journal of Cell Biology · doi:10.1083/jcb.202104129 · Cited by 15

A highly sensitive and versatile fluorescent biosensor for pathogen nucleic acid detection based on toehold-mediated strand displacement initiated primer exchange reaction

Zhang, Y., Li, Z., Su, W., Zhong, G., Zhang, X., Wu, Y. J., Situ, B., Xiao, Y., Yan, X., & Zheng, L. (2022) · Analytica Chimica Acta · doi:10.1016/j.aca.2022.340125 · Cited by 15

Porcine sialoadhesin suppresses type I interferon production to support porcine reproductive and respiratory syndrome virus infection

Liu, Y., Li, R., Qiao, S., Chen, X., Deng, R., & Zhang, G. (2020) · Veterinary Research · doi:10.1186/s13567-020-00743-7 · Cited by 14

The Interaction between SARS-CoV-2 Nucleocapsid Protein and UBC9 Inhibits MAVS Ubiquitination by Enhancing Its SUMOylation

Huang, C., Yin, Y., Pan, P., Huang, Y., Chen, S., Chen, J., Wang, J., Xu, G., Tao, X., Xiao, X., et al. (2023) · Viruses · doi:10.3390/v15122304 · Cited by 13

Genome integrity and inflammation in the nervous system

Aditi, A., & McKinnon, P. J. (2022) · DNA repair · doi:10.1016/j.dnarep.2022.103406 · Cited by 13

Transcriptome Analysis Identifies Strategies Targeting Immune Response-Related Pathways to Control Enterotoxigenic Escherichia coli Infection in Porcine Intestinal Epithelial Cells

Wu, Q., Cui, D., Chao, X.-Y., Chen, P., Liu, J., Wang, Y., Su, T., Li, M., Xu, R., Zhu, Y., et al. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.677897 · Cited by 12

Tyrosine phosphorylation of IRF3 by BLK facilitates its sufficient activation and innate antiviral response

Li, W.-W., Fan, X.-X., Zhu, Z., Cao, X.-J., Zhu, Z.-Y., Pei, D.-S., Wang, Y.-Z., Zhang, J.-Y., Wang, Y.-Y., & Zheng, H. (2023) · PLoS Pathogens · doi:10.1371/journal.ppat.1011742 · Cited by 11

Host Factors Modulate Virus-Induced IFN Production via Pattern Recognition Receptors

Wang, J., Dong, Y., Zheng, X., Ma, H., Huang, M., Fu, D., Liu, J., & Yin, Q. (2024) · Journal of Inflammation Research · doi:10.2147/jir.s455035 · Cited by 11

Role of the AIM2 Inflammasome in Cancer: Potential Therapeutic Strategies

Colarusso, C., Terlizzi, M., Caprio, S. D., Falanga, A., D’Andria, E., Bianca, R. D. D. V., & Sorrentino, R. (2025) · Biomedicines · doi:10.3390/biomedicines13020395 · Cited by 10

The cGAS-STING signaling pathway in the regulation of pulmonary infections: a systematic review

Xu, Q., & Zhu, J. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1628481 · Cited by 11

ID2 inhibits innate antiviral immunity by blocking TBK1- and IKKε-induced activation of IRF3

Yu, C., Wang, B., Zhu, Y., Zhang, C., Ren, L., Lei, X., Xiang, Z., Zhou, Z. L., Huang, H., Wang, J., et al. (2022) · Science Signaling · doi:10.1126/scisignal.abh0068 · Cited by 10

The influence of extracellular vesicles on tumor evolution and resistance to therapy

Baston, E., García-Agulló, J., & Peinado, H. (2025) · Physiological Reviews · doi:10.1152/physrev.00019.2024 · Cited by 9

The African swine fever virus p22 inhibits the JAK-STAT signaling pathway by promoting the TAX1BP1-mediated degradation of the type I interferon receptor

Ren, H., Wang, Y., Li, L., Shi, L.-F., Ma, Y., Fan, J.-H., Pan, X.-Y., Shao, H.-C., Zhang, Y., Han, S., et al. (2025) · PLoS Pathogens · doi:10.1371/journal.ppat.1013319 · Cited by 11

Mitotic inactivation of the cGAS‒MITA/STING pathways

Zhong, L., & Shu, H. (2021) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjab061 · Cited by 8

Heat Shock-Binding Protein 21 Regulates the Innate Immune Response to Viral Infection

Xu, Y., Yang, Q., Xue, B., Wang, X., Tian, R., Deng, R., Chen, S., Wang, X., Wang, L., Wang, C., et al. (2022) · Journal of Virology · doi:10.1128/jvi.00001-22 · Cited by 8

PWWP3A disrupts the assembly of VISA/MAVS signalosome to inhibit innate immune response against RNA viruses

Shi, M.-L., Wang, C., Chen, Z., Zhou, Y., Yu, L., Liu, Y., Guo, T., Shang, J., Xu, H., Zhang, Y., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-59421-x · Cited by 7

IRF1 amplifies HSV-1-triggered antiviral innate immunity in a feed-forward manner

Gao, M., Qi, Y., & Zhang, J. (2025) · Cell Insight · doi:10.1016/j.cellin.2025.100255 · Cited by 7

Picrasidine S Induces cGAS‐Mediated Cellular Immune Response as a Novel Vaccine Adjuvant

Ding, X., Sun, M., Guo, F., Qian, X., Yuan, H., Lou, W., Wang, Q., Lei, X., & Zeng, W. (2024) · Advanced Science · doi:10.1002/advs.202310108 · Cited by 7

Mycobacterial peptidyl prolyl isomerase A activates STING ‐ TBK1 ‐ IRF3 signaling to promote IFNβ release in macrophages

Sharma, A. K., Mal, S., Sahu, S. K., Bagchi, S., Majumder, D., Chakravorty, D., Saha, S., Kundu, M., & Basu, J. (2024) · FEBS Journal · doi:10.1111/febs.17261 · Cited by 7

SNX5 inhibits RLR-mediated antiviral signaling by targeting RIG-I-VISA signalosome

Li, J., Chen, T., Xie, T., Yang, Y., He, T., & Xu, L. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.11.121 · Cited by 7

SIRT2 inhibition enhances mitochondrial apoptosis in Brucella-infected bovine placental trophoblast cells

Zhang, M., Qi, L., Li, J., Yuan, N., Zhai, Y., Hao, M., Zhou, D., Liu, W., Jin, Y., & Wang, A. (2025) · Veterinary Research · doi:10.1186/s13567-025-01518-8 · Cited by 6

Mitochondrial DUT-M potentiates RLR-mediated antiviral signaling by enhancing VISA and TRAF2 association

Weng, G.-X., Ling, T., Hou, W., Li, S.-N., Chen, T., Zhang, Z., Wang, D., & Xu, L. (2021) · Molecular Immunology · doi:10.1016/j.molimm.2021.01.023 · Cited by 6

RNF138 Downregulates Antiviral Innate Immunity by Inhibiting IRF3 Activation

Zeng, X., Liu, C., Fan, J., Zou, J., Guo, M., & Sun, G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216110 · Cited by 6

When ASFV Infection Meets the cGAS‐STING Signaling Pathway

Chen, S., Shang, K., Wei, Y., Chen, J., Yu, Z., He, L., & Ding, K. (2024) · Transboundary and Emerging Diseases · doi:10.1155/2024/6898157 · Cited by 6

Epstein‐Barr virus regulates the life cycle and host cell biology by hijacking post‐translational modification

Zhang, X., Zhang, Y., Liu, W., & Luo, B. (2023) · Reviews in Medical Virology · doi:10.1002/rmv.2447 · Cited by 5

HSPBP1 facilitates cellular RLR-mediated antiviral response by inhibiting the K48-linked ubiquitination of RIG-I

Yang, Y., Huang, J., Li, S.-N., Li, J., Ling, T., Xie, T., & Xu, L. (2021) · Molecular Immunology · doi:10.1016/j.molimm.2021.03.002 · Cited by 5

HTATSF1 regulates innate antiviral immune response by orchestrating TRAF3-IRF3 and TRAF6-NF-κB pathways

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