The DOI matches its Crossref record; 130 of the 130 references it cites were found in a registry or an index.
Heterogeneity of Human CD4 + T Cells Against Microbes
Abstract
CD4 + T helper (Th) cells play a central role in the adaptive immune response by providing help to B cells and cytotoxic T cells and by releasing different types of cytokines in tissues to mediate protection against a wide range of pathogenic microorganisms. These functions are performed by different types of Th cells endowed with distinct migratory capacities and effector functions. Here we discuss how studies of the human T cell response to microbes have advanced our understanding of Th cell functional heterogeneity, in particular with the discovery of a distinct Th1 subset involved in the response to Mycobacteria and the characterization of two types of Th17 cells specific for extracellular bacteria or fungi. We also review new approaches to dissect at the clonal level the human CD4 + T cell response induced by pathogens or vaccines that have revealed an unexpected degree of intraclonal diversification and propose a progressive and selective model of CD4 + T cell differentiation.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“They can exert their protective function either directly, by acquiring effector and cytotoxic phenotypes, or indirectly, by the release of different types of cytokines that optimize durable CD8+ T cell responses and provide help to B cells for Ab production [131].”
From Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition) (2021) · cites this paper as [131]
In the citing paper
“analysis of Th17 cells in different tissue sites has revealed that Th17 cells may exhibit distinct transcriptional profiles associated with either homeostatic or pathogenic functions”
From TH17 cell heterogeneity and its role in tissue inflammation (2023) · cites this paper as [40]
Citations
Cites
Mosmann, T. R., Cherwinski, H. M., Bond, M. W., Giedlin, M. A., & Coffman, R. L. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.136.7.2348 · Cited by 7,559
Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., & Kuchroo, V. K. (2006) · Nature · doi:10.1038/nature04753 · Cited by 6,992
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
Sallusto, F., Lenig, D., Förster, R., Lipp, M., & Lanzavecchia, A. (1999) · Nature · doi:10.1038/44385 · Cited by 5,846 · cited 2×
“In contrast, CCR7−/CD62L− CD4+ T effector memory (Tem) cells represent a pool of more-differentiated circulating effector cells that can rapidly enter into tissue (5, 6) and, together with T tissue-resident memory (Trm) cells that remain at the site where the pathogen first entered (7, 8), provide a rapid and effectiv…”
BackgroundSelf-citationA distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Park, H., Li, Z., Yang, X. O., Chang, S. H., Nurieva, R., Wang, Y.-H., Wang, Y., Hood, L., Zhu, Z., Tian, Q., et al. (2005) · Nature Immunology · doi:10.1038/ni1261 · Cited by 4,265
The regulation of IL-10 production by immune cells
Saraiva, M., & O’Garra, A. (2010) · Nature reviews. Immunology · doi:10.1038/nri2711 · Cited by 3,293
Cua, D. J., Sherlock, J., Chen, Y., Murphy, C. A., Joyce, B., Seymour, B., Lucian, L., To, W., Kwan, S., Churakova, T., et al. (2003) · Nature · doi:10.1038/nature01355 · Cited by 2,906
Innate lymphoid cells — a proposal for uniform nomenclature
Spits, H., Artis, D., Colonna, M., Diefenbach, A., Disanto, J. D., Eberl, G., Koyasu, S., Locksley, R., McKenzie, A., Mebius, R., et al. (2013) · Nature reviews. Immunology · doi:10.1038/nri3365 · Cited by 2,380
Bendall, S. C., Simonds, E. F., Qiu, P., Amir, E.-A. D., Krutzik, P. O., Finck, R., Bruggner, R. V., Melamed, R., Trejo, A., Ornatsky, O. I., et al. (2011) · Science · doi:10.1126/science.1198704 · Cited by 2,279
Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP
Soumelis, V., Reche, P. A., Kanzler, H., Yuan, W., Edward, G., Homey, B., Gilliet, M. F., Ho, S., Antonenko, S. V., Lauerma, A., et al. (2002) · Nature Immunology · doi:10.1038/ni805 · Cited by 2,221
Bonecchi, R., Bianchi, G., Panina‐Bordignon, P., D’Ambrosio, D., Lang, R., Borsatti, A., Sozzani, S., Allavena, P., Gray, P. A., Mantovani, A., et al. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.187.1.129 · Cited by 2,016
Research works printed but not linked: 2
- Eyerich S, 2009, J. Clin. Investig., 119, 3573
- Picker LJ, 1990, Am. J. Pathol., 136, 1053
Cited by
Sorted by citations
Items 201–300 of 335
Lee, S., Kang, H., Chu, K., Basak, S., Lee, D., Moon, E., & Quan, F. (2020) · Vaccines · doi:10.3390/vaccines8030428 · Cited by 12
T-helper-2 cells and atopic disease: lessons learnt from inborn errors of immunity
Ma, C. S. (2023) · Current Opinion in Immunology · doi:10.1016/j.coi.2023.102298 · Cited by 11
Th17 associated cytokines in sputum samples from patients with cystic fibrosis
Oshalim, M., Johansson, E., Rabe, H., Gilljam, M., Lindblad, A., & Jönsson, B. (2020) · Pathogens and Disease · doi:10.1093/femspd/ftaa050 · Cited by 12
Liposome Vaccine for Active Regulation of Cellular and Humoral Immunity
Luo, L., Luo, Z., Wang, L., Hu, Y., Zhang, J., Yin, H., & You, J. (2023) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.3c00536 · Cited by 11
Kar, R., Chattopadhyay, S., Sharma, A., Sharma, K. M. T. K., Sinha, S., Arimbasseri, G. A., & Patil, V. S. (2024) · Immunology · doi:10.1111/imm.13783 · Cited by 11
Saz-Leal, P., Ligon, M. M., Diez-Rivero, C. M., García-Ayuso, D., Mohanty, S., Viñuela, M., Real-Arévalo, I., Conejero, L., Brauner, A., Subiza, J. L., et al. (2024) · Vaccines · doi:10.3390/vaccines12050535 · Cited by 11
Kudryavtsev, I. V., Серебрякова, М. К., Zhiduleva, E. V., Murtazalieva, P., Titov, V., Malashicheva, A., Shishkova, А. А., Semenova, D., Irtyuga, O. B., Isakov, D., et al. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00604 · Cited by 11
Plant-Based Support of Respiratory Health during Viral Outbreaks
Thirumurugan, R., Sakthivel, L. P., & Komarnytsky, S. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c06227 · Cited by 10
Berberine: A natural modulator of immune cells in multiple sclerosis
Yazdanpanah, E., Dadfar, S., Shadab, A., Orooji, N., Nemati, M., Pazoki, A., Esmaeili, S., Baharlou, R., & Haghmorad, D. (2024) · Immunity Inflammation and Disease · doi:10.1002/iid3.1213 · Cited by 10
Ledoult, E., Groh, M., Kahn, J., Trauet, J., Bouaziz, J., Caristan, A., Cottin, V., Dubucquoi, S., Etienne, N., Golden, C., et al. (2019) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2019.08.049 · Cited by 11
Editorial: CD4+ T cells in HIV: A Friend or a Foe?
Govindaraj, S., Babu, H., Kannanganat, S., Vaccari, M., Petrovas, C., & Velu, V. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1203531 · Cited by 16
Are T cells helpful for COVID-19: the relationship between response and risk
Griffin, D. E. (2020) · Journal of Clinical Investigation · doi:10.1172/jci142081 · Cited by 10
Nguyen, X., Dauvilliers, Y. A., Queriault, C., Pérals, C., Romieu, R., Paulet, P.-E., Bernard‐Valnet, R., Fazilleau, N., & Liblau, R. (2018) · Journal of Autoimmunity · doi:10.1016/j.jaut.2018.07.021 · Cited by 10
T helper cell trafficking in autoimmune kidney diseases
Riedel, J.-H., Turner, J., & Panzer, U. (2021) · Cell and Tissue Research · doi:10.1007/s00441-020-03403-6 · Cited by 10
Gearing up for battle: Harnessing adaptive T cell immunity against gram-negative pneumonia
Gao, C. A., Morales‐Nebreda, L., & Pickens, C. I. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.934671 · Cited by 9
Repertoire-based mapping and time-tracking of T helper cell subsets in scRNA-Seq
Lukyanov, D. K., Kriukova, V., Ladell, K., Shagina, I. A., Staroverov, D. B., Минасян, Б. Э., Fedosova, A. S., Shelyakin, P. V., Suchalko, O. N., Komkov, A. Y., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1536302 · Cited by 9
Huang, D., Zhang, C., Wang, P., Li, X., Gao, L., & Zhao, C. (2022) · DNA and Cell Biology · doi:10.1089/dna.2022.0149 · Cited by 10
Schroeder, R., Grzywa, R., Wirtz, C. R., Sieńczyk, M., & Burster, T. (2019) · Analytical Biochemistry · doi:10.1016/j.ab.2019.113488 · Cited by 9
Ayeldeen, G. M., Badr, B. M., Awaji, A. A., Gaber, D. A., Elelwany, D. A., Abdulqader, A. K. A., Shaker, O. G., & Abd‐Elmawla, M. A. (2025) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5c00299 · Cited by 8
Lu, Y., Ning, H., Kang, J., Bai, G., Zhou, L., Kang, Y., Wu, Z., Tian, M., Zhao, J., Ma, Y., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.871135 · Cited by 8
A Th1-like CD4+ T-cell Cluster That Predicts Disease-free Survival in Early-stage Lung Cancer
Yanagihara, A., Yamasaki, S., Hashimoto, K., Taguchi, R., Umesaki, T., Imai, H., Kaira, K., Nitanda, H., Sakaguchi, H., Ishida, H., et al. (2023) · Cancer Research Communications · doi:10.1158/2767-9764.crc-23-0167 · Cited by 8
Perrone, C., Bozzano, F. M., Bello, M. G. D., Zotto, G. D., Antonini, F., Munari, E., Maggi, E., Moretta, F., Hajabbas-Farshchi, A., Pariscenti, G., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1332781 · Cited by 8
Perri, G., Boas, V. G. V., Nogueira, M. R. S., Mello, E. J. F., Coelho, A. L., Posadas, E. M., Hogaboam, C. M., Cavassani, K. A., & Campanelli, A. P. (2024) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-024-03676-8 · Cited by 8
Developmental immunology and role of host defenses in fetal and neonatal susceptibility to infection
Lewis, D. B., Weitkamp, J.-H., & Levy, O. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-79525-8.00013-5 · Cited by 7
Human primed ILCPs support endothelial activation through NF-κB signaling
Vanoni, G., Ercolano, G., Candiani, S., Rutigliani, M., Lanata, M., Derré, L., Marcenaro, E., Schneider, P., Romero, P. J., Jandus, C., et al. (2021) · eLife · doi:10.7554/elife.58838 · Cited by 9
Won, H. Y., Shin, J. H., Oh, S., Jeong, H., & Hwang, E. S. (2017) · Scientific Reports · doi:10.1038/s41598-017-17073-y · Cited by 9
Tortosa-Carreres, J., Quiroga‐Varela, A., Castillo-Villalba, J., Piqueras, M., Ramió-Torrentà, L. L., Cubas-Núñez, L., Gasqué-Rubio, R., Quintanilla‐Bordás, C., Huertas‐Pons, J. M., Miguela, A., et al. (2023) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2023.104997 · Cited by 8
Exploring the immune characteristions of CRKP pneumonia at single-cell level
Sun, Y., Chen, F., Ma, H., Wang, D., Wang, D., Zhang, J., Jiang, Z., Xia, R., Tian, T., & Zhang, W. (2024) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2024.108574 · Cited by 7
What can primary immunodeficiencies teach us about Th9 cell differentiation and function?
Worley, L., Tangye, S. G., & Ma, C. S. (2018) · Immunology and Cell Biology · doi:10.1111/imcb.12215 · Cited by 7
Brenna, E., & McMichael, A. J. (2021) · DNA and Cell Biology · doi:10.1089/dna.2021.0520 · Cited by 9
Mechanistic and Biomarker Studies to Demonstrate Immune Tolerance in Multiple Sclerosis
Docampo, M. J., Lutterotti, A., Sospedra, M., & Martinꝉ, R. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2021.787498 · Cited by 7
Niebuhr, M., Bahreini, F., Fähnrich, A., Bomholt, C., Bieber, K., Schmidt, E., Ibrahim, S. M., Hammers, C. M., & Kalies, K. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1006941 · Cited by 7
Newbrook, K., Khan, N. C., Fisher, A., Chong, K., Gubbins, S., Davies, W. C., Sanders, C., Busquets, M. G., Cooke, L., Corla, A., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1328820 · Cited by 7
Single‐cell analysis of CD8 T lymphocyte diversity during adaptive immunity
Arsenio, J. (2019) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1475 · Cited by 9
Rezk, A., Li, R., & Bar‐Or, A. (2020) · Scientific Reports · doi:10.1038/s41598-020-71750-z · Cited by 8
Lei, C., Yu, Q., Wang, H., Liu, J., Chen, S., Zhao, Z., & Qiu, L. (2021) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.24035 · Cited by 7
Wei, Z., Gong, B., Li, X., Chen, C., & Zhao, Q. (2024) · BMC Cancer · doi:10.1186/s12885-024-13044-5 · Cited by 6
Hu, D., Chen, M., Li, X., Morin, P., Daley, S., Han, Y., Hemberg, M., Weiner, H. L., & Xia, W. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251320123 · Cited by 8
Fighting the enemy within: Systemic immune defense against mucosal Salmonella infection
Nguyen, A. T., & McSorley, S. J. (2024) · Immunology Letters · doi:10.1016/j.imlet.2024.106930 · Cited by 7
Rims, C. R., Uchtenhagen, H., Brooks, K., Ng, B., Posso, S. E., Carlin, J. S., Kwok, W. W., Buckner, J. H., & James, E. A. (2024) · Clinical & Experimental Immunology · doi:10.1093/cei/uxae102 · Cited by 6
Rao, G., Mack, C. D., Nguyen, T., Wong, N. S. M., Payne, K. J., Worley, L., Gray, P. E., Wong, M., Hsu, P. S., Stormon, M., et al. (2024) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2024.11.031 · Cited by 6
Romero-Martín, L., Tarrés-Freixas, F., Pedreño-López, N., de la Concepción, M. L. R., Cunyat, F., Hartigan-O’Connor, D. J., Carrillo, J., Mothe, B., Blanco, J., Ruiz‐Riol, M., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.928039 · Cited by 6
Yang, L., Zhao, N., & Du, Y. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.1027026 · Cited by 6
Assessing Trends in Cytokine–CYP Drug Interactions and Relevance to Drug Dosing
Sawant‐Basak, A., Olabode, D., Dai, D., Vishwanathan, K., & Phipps, A. (2024) · Drug Metabolism and Disposition · doi:10.1124/dmd.123.001499 · Cited by 6
Modulation of CD4+ T Helper Cell Memory Responses in the Human Skin
Padovan, E. (2017) · International Archives of Allergy and Immunology · doi:10.1159/000477728 · Cited by 6
A Single-Cell Perspective on Memory T-Cell DifferentiationPreprint
Kretschmer, L., Busch, D. H., & Buchholz, V. R. (2021) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a038067 · Cited by 6
Bukali, L., Engel, J. A., Oyong, D. A., Rivera, F. D. L., Soon, M. S. F., Andrew, D., Dooley, N. L., Nalubega, M., Mukhiya, R., Frame, T. C. M., et al. (2025) · medRxiv · doi:10.1101/2025.04.09.25325416 · Cited by 6
Ohnmacht, C., & Eyerich, S. (2021) · Handbook of experimental pharmacology · doi:10.1007/164_2021_486 · Cited by 5
Lian, J., Tang, W., Yang, Y., Vaidyanathan, R., Gonçales, V. R., Arman, S., Tilley, R. D., & Gooding, J. J. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c23209 · Cited by 5
Temperature Plays an Essential Regulatory Role in the Tumor Immune Microenvironment
Zhang, B., Wang, Y., Zhao, Z., Han, B., Yang, J. B., Sun, Y., Zhang, B., Zang, Y., & Guan, H. (2021) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2021.3030 · Cited by 5
Peripheral Follicular Helper T Cells in Acute Viral Diseases: A Perspective On Dengue
Sánchez-Vargas, L. A., & Mathew, A. (2019) · Future Virology · doi:10.2217/fvl-2018-0197 · Cited by 5
Takei, S., Yamasaki, S., Yamaguchi, O., Mouri, A., Shiono, A., Miura, Y., Hashimoto, K., Imai, H., Kaira, K., Ichiki, Y., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-71161-0 · Cited by 4
Jiang, Q., Lindelauf, C., van Unen, V., Jong, A. E. V. D. M., Koning, F., & Pascutti, M. F. (2025) · Cytometry Part A · doi:10.1002/cyto.a.24914 · Cited by 4
Mazzoni, A., Annunziato, F., & Maggi, L. (2023) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000991 · Cited by 4
Infant respiratory infections modulate lymphocyte homing to breast milk
Zheng, Y., Correa‐Silva, S., Rodrigues, R. M., de Souza, E. C., da Fonseca, F. A. M., Gilio, A. E., Carneiro-Sampaio, M. M. S., & Palmeira, P. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1481416 · Cited by 4
Radford, F., Tyagi, S., Gennaro, M. L., Pine, R. I., & Bushkin, Y. (2016) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.2017018316 · Cited by 4
Gillard, J., van Schuppen, E., & Diavatopoulos, D. A. (2019) · Advances in experimental medicine and biology · doi:10.1007/5584_2019_404 · Cited by 4
Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infection
Parsa, R., de Assis, H. C., Castro, T. B. R., dos Reis, G. L., Sushil, A., Hartweger, H., Bilate, A. M. B., & Mucida, D. (2026) · Nature Immunology · doi:10.1038/s41590-026-02451-4 · Cited by 5
Mucosal Vaccine Development: From Adjuvant Design to Next-Generation Delivery Strategies
Lee, W.-H., & Kim, E. (2026) · Biomedicines · doi:10.3390/biomedicines14051060 · Cited by 5
Role of Immune Cells in the Tumor Microenvironment
Özdemir, B. H. (2023) · Interdisciplinary cancer research · doi:10.1007/16833_2023_143 · Cited by 2
Sorafenib inhibits multiple sclerosis by regulating T cell differentiation
Wang, H., Wang, S., Wang, J., Fang, Y., Li, J., Shen, Y., & Guo, J. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.111872 · Cited by 8
Phenotypic Heterogeneity inMycobacterium tuberculosis
Dhar, N., McKinney, J. D., & Manina, G. (2017) · ASM Press eBooks · doi:10.1128/9781555819569.ch32 · Cited by 2
Villanueva‐Romero, R., Cabrera‐Martín, A., Álvarez-Corrales, E., Carrión, M., Pérez‐García, S., Lamana, A., Castro, D. M., Martínez, C., Gomariz, R. P., Gutiérrez‐Cañas, I., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042346 · Cited by 4
Aniagyei, W., Adjei, J. K., Adankwah, E., Seyfarth, J., Mayatepek, E., Antwi‐Berko, D., Sakyi, S. A., Debrah, L. B., Debrah, A. Y., Hoerauf, A. M., et al. (2022) · Clinical Infectious Diseases · doi:10.1093/cid/ciac428 · Cited by 3
Natural products for treating cytokine storm-related diseases: Therapeutic effects and mechanisms.
Liu, M., Wang, Q., Xu, W., Wu, J., Xu, X., Yang, H., & Li, X. (2023) · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · doi:10.1016/j.biopha.2023.115555 · Cited by 3
Yang, S., Chen, H., Wei, B., Xiang, M., Hu, Z.-B., Peng, Z., Lin, H., & Sun, J. (2018) · Inflammation · doi:10.1007/s10753-018-0833-4 · Cited by 3
Cell surface cathepsin G can be used as an additional marker to distinguish T cell subsets
Penczek, A., & Burster, T. (2019) · Biomedical Reports · doi:10.3892/br.2019.1198 · Cited by 3
Default polyfunctional T helper 1 response to ample signal 1 alone
Danelli, L., Cornish, G. H., Merkenschlager, J., & Kassiotis, G. (2020) · Cellular and Molecular Immunology · doi:10.1038/s41423-020-0415-x · Cited by 3
Zhang, L., Feng, T., & Liu, H. (2022) · Disease Markers · doi:10.1155/2022/5967429 · Cited by 2
Mouri, A., Kaira, K., Yamaguchi, O., Shiono, A., Miura, Y., Hashimoto, K., Yamasaki, S., Nishihara, F., Imai, H., Kobayashi, K., et al. (2025) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-025-04113-0 · Cited by 2
Lv, Y., Xiao, Z., Kuang, L., Omindo, W. W., Zhan, X., Tang, W., Liu, X., Wang, X., Fu, L., Zhang, R., et al. (2026) · European journal of medical research · doi:10.1186/s40001-026-04408-7 · Cited by 2
In vitro differentiated human CD4+ T cells produce hepatocyte growth factor
Ford, S. L., Buus, T. B., Nastasi, C., Geisler, C., Bonefeld, C. M., Ødum, N., & Woetmann, A. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1210836 · Cited by 2
Shi, J., Shen, L., Xiao, Y., Wan, C., Wang, B., Zhou, P., Zhang, J., Han, W., Hu, R., Yu, F., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1450782 · Cited by 2
Escalation of Germinal Center Responses in Chronic Litomosoides sigmodontis Filarial Infection
Steffen, T., Ajendra, J., Koschel, M., Palmen, A., Wegner, H., Risch, F., Bach, L., Ritter, M., Hübner, M. P., & Baumjohann, D. (2025) · European Journal of Immunology · doi:10.1002/eji.202451400 · Cited by 2
A Panoramic View of the Immune Response to Trypanosoma cruzi Infection
Acevedo, G. R., Girard, M. C., & Gómez, K. A. (2019) · Birkhäuser advances in infectious diseases · doi:10.1007/978-3-030-00054-7_3 · Cited by 2
Rajaei, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818731-9.00038-0 · Cited by 2
Choy, J. C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809657-4.99563-2 · Cited by 2
Flow Cytometry Applied to the Diagnosis of Primary Immunodeficiencies
Martínez‐Gallo, M., & García-Prat, M. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.89743 · Cited by 1
Expansion of multiple CD4+ T-cell lineages in lymphocytic variant hypereosinophilic syndrome
Anderson, C. F., Makiya, M. A., Xiong, K., Penrod, L., Wetzler, L., Ware, J. M., Constantine, G. M., Khoury, P., & Klion, A. D. (2025) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2025.04.027 · Cited by 1
Zhang, J., & Qiu, X. (2025) · Scientific Reports · doi:10.1038/s41598-025-14007-x · Cited by 2
Li, K., Zhu, S., Ye, C. J., Ding, Y., Liu, J., Wang, Y., Wang, Z., Li, W., Yang, D., Wang, X., et al. (2025) · Journal of Translational Internal Medicine · doi:10.1515/jtim-2025-0053 · Cited by 1
Yan, P., Li, R., Yuan, X.-Y., Wang, Y., Lan, L.-J., Yu, X.-P., & Liu, D.-F. (2026) · World Journal of Hepatology · doi:10.4254/wjh.v18.i2.113004 · Cited by 1
Inflammatory Dysregulation, Asthma, and Obesity in Children: What is the Relationship?
Duran, S., Reichenbach, A., & Rastogi, D. (2026) · Journal of Inflammation Research · doi:10.2147/jir.s546304 · Cited by 1
Pathogenicity of acquired immunity in human diseases
Hirahara, K. (2019) · Seminars in Immunopathology · doi:10.1007/s00281-019-00739-2 · Cited by 1
Modular Approaches to Understand the Immunobiology of Human Immunodeficiency Virus Latency
Wolf, G. S., & Singh, N. J. (2021) · Viral Immunology · doi:10.1089/vim.2020.0171 · Cited by 1
Immunophenotypes of anti-SARS-CoV-2 responses associated with fatal COVID-19
Šelb, J., Bitežnik, B., Bidovec‐Stojkovič, U., Rituper, B., Osolnik, K., Kopač, P., Svetina, P., Porenta, K. C., Šifrer, F., Lorber, P., et al. (2022) · ERJ Open Research · doi:10.1183/23120541.00216-2022 · Cited by 3
Kobakova, Y. A., Moneva-Sakelarieva, M. G., Konstantinov, S., Momekov, G., Semerdzhieva, N. E., Ivanova, S. A., Atanasova, V. P., Atanasov, P. Y., & Becheva, M. S. V. (2024) · Pharmacia · doi:10.3897/pharmacia.71.e135468 · Cited by 1
Fiorino, S., Carusi, A., Hong, W., Cernuschi, P., Gallo, C. G., Ferrara, E., Maloberti, T., Visani, M., Lari, F., de Biase, D., et al. (2022) · AIMS Microbiology · doi:10.3934/microbiol.2022029 · Cited by 1
Hellberg, S., Raffetseder, J., Rundquist, O., Magnusson, R., Papapavlou, G., Jenmalm, M. C., Ernerudh, J., & Gustafsson, M. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.05.370700 · Cited by 1
Immunology of the Fetus and Newborn
Weitkamp, J.-H., Lewis, D. B., & Levy, O. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-82823-9.00032-5 · Cited by 1
Fert, A., Richard, J., Marchand, L. R., Planas, D., Routy, J., Chomont, N., Finzi, A., & Ancuța, P. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.15.580166 · Cited by 1
Editorial: Pathogenic roles of T cells in autoimmunity
Xia, J., Tang, J., Fu, Q., & Lin, J. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1401459 · Cited by 1
Hu, D., Chen, M., Li, X.-Y., Morin, P., Daley, S., Han, Y., Hemberg, M., Weiner, H., & Xia, W.-M. (2024) · bioRxiv · doi:10.1101/2024.05.28.596276 · Cited by 2
Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infectionPreprint
Parsa, R., de Assis, H. C., Castro, T. B. R., dos Reis, G. L., Sushil, A., Hartweger, H., Bilate, A. M. B., & Mucida, D. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.25.672130 · Cited by 1
From the Thymus to the Mucosa: A Three-Decade Journey
Littman, D. R. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1790016
OBSOLETE: Transplant Arteriosclerosis
Choy, J. C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.99563-1
IL-33 no carcinoma espinocelular de pele
Boas, V. G. V. (2018) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.25.2019.tde-14052019-180319
Transcriptional control of tissue-resident memory T cell generation
Cvetkovski, F. (2019) · doi:10.7916/d8-n16c-b343
Kumar, R., Ng, S. S., & Engwerda, C. R. (2018) · Springer eBooks · doi:10.1007/978-1-4614-8326-7_136
Metadata
- Authors
- Sallusto, F.
- Affiliations
- Institute for Research in Biomedicine (CH)
- Corresponding author
- Sallusto, Federica
- ORCID
- Sallusto, Federica
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 2016-05-20
- Volume
- 34
- Issue
- 1
- Pages
- 317-334
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2358115279
- Cited by
- 336
- References
- 130
- Citations by year
- 2026: 19 · 2025: 20 · 2024: 28 · 2023: 28 · 2022: 36 · 2021: 43 · 2020: 46 · 2019: 38 · 2018: 34 · 2017: 37 · 2016: 7
- FWCI
- 3.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Immunology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Keywords
- CD4+ T cells, Th1 cells, Th17 cells, mycobacteria, extracellular bacteria, T cell differentiation, vaccine-induced T cell responses
- MeSH terms
- Animals, Bacterial Infections, Cell Differentiation, Clone Cells, Cytotoxicity, Immunologic, Humans, Mycoses, Receptors, Antigen, T-Cell, Vaccines, CD4 Antigens, Th1 Cells, Biodiversity, Adaptive Immunity, Immunity, Humoral, Th17 Cells, Clonal Selection, Antigen-Mediated
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review