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CCR5 Revisited: How Mechanisms of HIV Entry Govern AIDS Pathogenesis

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Human CD4 + T Cell Responses to an Attenuated Tetravalent Dengue Vaccine Parallel Those Induced by Natural Infection in Magnitude, HLA Restriction, and Antigen Specificity

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HIV persistence in subsets of CD4+ T cells: 50 shades of reservoirs

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Progesterone Dampens Immune Responses in In Vitro Activated CD4+ T Cells and Affects Genes Associated With Autoimmune Diseases That Improve During Pregnancy

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A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells

Chang, Y., Rossetti, M. M., Vlamakis, H. C., Casero, D., Sunga, G. M., Harre, N., Miller, S. A., Humphries, R. M., Stappenbeck, T. S., Simpson, K. W., et al. (2018) · Mucosal Immunology · doi:10.1038/s41385-018-0022-7 · Cited by 62

Trefoil Factor Family (TFF) Peptides and Their Links to Inflammation: A Re-evaluation and New Medical Perspectives

Hoffmann, W. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094909 · Cited by 65

The regulation of CD4+ T cells during malaria

Kumar, R., Loughland, J. R., Ng, S. S., Boyle, M. J., & Engwerda, C. R. (2019) · Immunological Reviews · doi:10.1111/imr.12804 · Cited by 61

Transcriptomic Profiling of Human Effector and Regulatory T Cell Subsets Identifies Predictive Population Signatures

Höllbacher, B., Duhen, T. M., Motley, S., Klicznik, M. M., Gratz, I. K., & Campbell, D. (2020) · ImmunoHorizons · doi:10.4049/immunohorizons.2000037 · Cited by 60

CD4+ T Cell Differentiation in Chronic Viral Infections: The Tfh Perspective

Vella, L. A., Herati, R. S., & Wherry, E. J. (2017) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2017.10.001 · Cited by 60

Macrophage barrier in the tumor microenvironment and potential clinical applications

Ji, S., Shi, Y., & Yin, B. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-023-01424-6 · Cited by 62

Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity

Hiltensperger, M., Beltrán, E., Kant, R., Tyystjärvi, S., Lepennetier, G., Moreno, H. D., Bauer, I., Grassmann, S. A., Jarosch, S., Schober, K., et al. (2021) · Nature Immunology · doi:10.1038/s41590-021-00948-8 · Cited by 65

PPAR-γ regulates the effector function of human T helper 9 cells by promoting glycolysis

Bertschi, N., Steck, O., Luther, F., Bazzini, C., von Meyenn, L., Schärli, S., Vallone, A., Felser, A., Keller, I., Friedli, O., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-38233-x · Cited by 61

Atypical Human Effector/Memory CD4+ T Cells With a Naive-Like Phenotype

Caccamo, N., Joosten, S. A., Ottenhoff, T. H. M., & Dieli, F. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02832 · Cited by 56

Th1 and Innate Lymphoid Cells Accumulate in Primary Sclerosing Cholangitis-associated Inflammatory Bowel Disease

Gwela, A., Siddhanathi, P., Chapman, R. W., Travis, S. P. L., Powrie, F. M., Arancibia-Cárcamo, C. V., & Geremia, A. (2017) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjx050 · Cited by 57

Pathogenesis of infections in HIV-infected individuals: insights from primary immunodeficiencies

Zhang, Q., Frange, P., Blanche, S., & Casanova, J. (2017) · Current Opinion in Immunology · doi:10.1016/j.coi.2017.09.002 · Cited by 59

IL17eScan: A Tool for the Identification of Peptides Inducing IL-17 Response

Gupta, S., Mittal, P., Madhu, M. K., & Sharma, V. K. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01430 · Cited by 58

Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice

Miller, S. M., Cybulski, V., Whitacre, M., Bess, L. S., Livesay, M. T., Walsh, L. M., Burkhart, D. J., Bazin, H. G., & Evans, J. T. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00406 · Cited by 58

IL-2–mTORC1 signaling coordinates the STAT1/T-bet axis to ensure Th1 cell differentiation and anti-bacterial immune response in fish

Ai, K., Li, K., Jiao, X., Zhang, Y., Li, J., Zhang, Q., Wei, X., & Yang, J. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010913 · Cited by 55

Evaluation of Whole-Cell and Acellular Pertussis Vaccines in the Context of Long-Term Herd Immunity

Szwejser-Zawislak, E., Wilk, M. M., Piszczek, P., Krawczyk, J., Wilczyńska, D., & Hozbor, D. F. (2022) · Vaccines · doi:10.3390/vaccines11010001 · Cited by 55

New Insights into Multiple Sclerosis Mechanisms: Lipids on the Track to Control Inflammation and Neurodegeneration

Podbielska, M., O’Keeffe, J., & Pokryszko‐Dragan, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147319 · Cited by 55

Immune Response to Borrelia : Lessons from Lyme Disease Spirochetes

Bockenstedt, L. K., Wooten, R. M., & Baumgarth, N. (2020) · Current Issues in Molecular Biology · doi:10.21775/cimb.042.145 · Cited by 66

A Clinical Approach for the Use of VIP Axis in Inflammatory and Autoimmune Diseases

Martínez, C., Juarranz, Y., Gutiérrez‐Cañas, I., Carrión, M., Pérez‐García, S., Villanueva‐Romero, R., Castro, D. M., Lamana, A., Mellado, M., González‐Álvaro, I., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms21010065 · Cited by 52

A high‐dimensional cytometry atlas of peripheral blood over the human life span

Jalali, S., Harpur, C. M., Piers, A. T., Auladell, M. A., Perriman, L., Li, S., An, K., Anderson, J., Berzins, S. P., Licciardi, P. V., et al. (2022) · Immunology and Cell Biology · doi:10.1111/imcb.12594 · Cited by 47

T helper cell subsets: diversification of the field

Zielinski, C. E. (2023) · European Journal of Immunology · doi:10.1002/eji.202250218 · Cited by 53

Neoself-antigens are the primary target for autoreactive T cells in human lupus

Mori, S., Kohyama, M., Yasumizu, Y., Tada, A., Tanzawa, K., Shishido, T., Kishida, K., Jin, H., Nishide, M., Kawada, S., et al. (2024) · Cell · doi:10.1016/j.cell.2024.08.025 · Cited by 55

Dynamic Response Genes in CD4+ T Cells Reveal a Network of Interactive Proteins that Classifies Disease Activity in Multiple Sclerosis

Hellberg, S., Eklund, D., Gawel, D. R., Köpsén, M., Zhang, H., Nestor, C. E., Kockum, I. S., Olsson, T. P., Skogh, T., Kastbom, A., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.08.036 · Cited by 47

Social-Stress-Responsive Microbiota Induces Stimulation of Self-Reactive Effector T Helper Cells

Werbner, M., Barsheshet, Y., Werbner, N., Zigdon, M., Averbuch, I., Oren, Z., Brant, B., Elliott, E., Gelberg, S., Titelbaum, M., et al. (2019) · mSystems · doi:10.1128/msystems.00292-18 · Cited by 49

OMIP ‐ 063 : 28‐Color Flow Cytometry Panel for Broad Human Immunophenotyping

Payne, K. J., Li, W., Salomon, R., & Ma, C. S. (2020) · Cytometry Part A · doi:10.1002/cyto.a.24018 · Cited by 49

The Anti-Inflammatory Mediator, Vasoactive Intestinal Peptide, Modulates the Differentiation and Function of Th Subsets in Rheumatoid Arthritis

Villanueva‐Romero, R., Gutiérrez‐Cañas, I., Carrión, M., Pérez‐García, S., Seoane, I. V., Martínez, C., Gomariz, R. P., & Juarranz, Y. (2018) · Journal of Immunology Research · doi:10.1155/2018/6043710 · Cited by 48

Transcriptomic Analysis of CD4+ T Cells Reveals Novel Immune Signatures of Latent Tuberculosis

Burel, J. G., Arlehamn, C. S. L., Khan, N., Seumois, G., Greenbaum, J., Taplitz, R., Gilman, R. H., Saito, M., Vijayanand, P., Sette, A., et al. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1800118 · Cited by 45

CD4+ T cell differentiation in infection: amendments to the Th1/Th2 axiom

Feng, C. G., & Jankovic, D. L. (2015) · Directory of Open access Books (OAPEN Foundation)

T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines

Becattini, S., Latorre, D., Mele, F., Foglierini, M., Gregorio, C. D., Cassotta, A., Fernandez, B., Kelderman, S., Schumacher, T. N., Corti, D., et al. (2015) · Archive ouverte UNIGE (University of Geneva) · Cited by 1

Functional heterogeneity of human memory CD4 + T cell clones primed by pathogens or vaccines

Becattini, S., Latorre, D., Mele, F., Foglierini, M., Gregorio, C. D., Cassotta, A., Fernandez, B., Kelderman, S., Schumacher, T. N., Corti, D., et al. (2014) · Science · doi:10.1126/science.1260668 · Cited by 323

Clonal Expansion and Differentiation to Effector Function in Normal CD4 T Cell Subpopulations

Bottomly, K., Luqman, M., Murray, J. S., West, J., Woods, A., & Carding, S. R. (1989) · Springer eBooks · doi:10.1007/978-3-642-83755-5_80 · Cited by 3

A functional dichotomy in CD4+ T lymphocytes

Bottomly, K. (1988) · Immunology Today · doi:10.1016/0167-5699(88)91308-4 · Cited by 367