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Innate Immunity and Neurodegeneration
Open accessAbstract
The innate immune system plays diverse roles in health and disease. It represents the first line of defense against infection and is involved in tissue repair, wound healing, and clearance of apoptotic cells and cellular debris. Excessive or nonresolving innate immune activation can lead to systemic or local inflammatory complications and cause or contribute to the development of inflammatory diseases. In the brain, microglia represent the key innate immune cells, which are involved in brain development, brain maturation, and homeostasis. Impaired microglial function, either through aberrant activation or decreased functionality, can occur during aging and during neurodegeneration, and the resulting inflammation is thought to contribute to neurodegenerative diseases. This review highlights recent advances in our understanding of the influence of innate immunity on neurodegenerative disorders such as Alzheimer's disease, amyotrophic lateral sclerosis, Parkinson's disease, and Huntington's disease.
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“Both receptors are expressed in immune cells, such as microglia, but also in neurons [3, 4, 7, 8].”
From Neurodegenerative disease-associated microRNAs acting as signaling molecules modulate CNS neuron structure and viability (2025) · cites this paper as [3]
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“Aged glial cells respond less efficiently to antigens, including amyloid-β (Aβ) and α-synuclein, and have reduced phagocytic and antiinflammatory capacity (161–163).”
From Connecting aging biology and inflammation in the omics era (2022) · cites this paper as [162]
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“Toll-like receptors (TLRs) contribute to such central nervous system (CNS) injury by triggering inflammation and cell-autonomous damage [3, 4].”
From Neurodegenerative disease-associated microRNAs acting as signaling molecules modulate CNS neuron structure and viability (2025) · cites this paper as [3]
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Neuroinflammation in Alzheimer's disease
Heneka, M. T., Carson, M. J., Khoury, J. E., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., et al. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)70016-5 · Cited by 6,226
Self-citationKalia, L. V., & Lang, A. E. (2015) · The Lancet · doi:10.1016/s0140-6736(14)61393-3 · Cited by 6,184
The amyloid hypothesis of Alzheimer's disease at 25 years
Selkoe, D. J., & Hardy, J. (2016) · EMBO Molecular Medicine · doi:10.15252/emmm.201606210 · Cited by 6,164
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science · doi:10.1126/science.1194637 · Cited by 5,175
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
Paolicelli, R. C., Bolasco, G., Pagani, F., Maggi, L., Scianni, M., Panzanelli, P., Giustetto, M., Ferreira, T. A., Guiducci, E., Dumas, L., et al. (2011) · Science · doi:10.1126/science.1202529 · Cited by 4,244
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
Block, M. L., Zecca, L., & Hong, J.-S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2038 · Cited by 4,110
ATP mediates rapid microglial response to local brain injury in vivo
Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., Littman, D. R., Dustin, M. L., & Gan, W.-B. (2005) · Nature Neuroscience · doi:10.1038/nn1472 · Cited by 3,913
Host microbiota constantly control maturation and function of microglia in the CNS
Erny, D., Hrabě de Angelis, A. L., Jaitin, D., Wieghofer, P., Staszewski, O., David, E., Keren-Shaul, H., Mahlakoiv, T., Jakobshagen, K., Buch, T., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.4030 · Cited by 3,569
Complement and microglia mediate early synapse loss in Alzheimer mouse models
Hong, S., Beja-Glasser, V. F., Nfonoyim, B. M., Frouin, A., Li, S., Ramakrishnan, S., Merry, K. M., Shi, Q., Rosenthal, A., Barres, B. A., et al. (2016) · Science · doi:10.1126/science.aad8373 · Cited by 3,343
The Classical Complement Cascade Mediates CNS Synapse Elimination
Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.036 · Cited by 3,313
Research works printed but not linked: 1
- Martin P, 2015, World Alzheimer report 2015: the global impact of dementia
Cited by
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Reisz, J. A., Barrett, A. S., Nemkov, T. G., Hansen, K. C., & D’Alessandro, A. (2018) · Expert Review of Proteomics · doi:10.1080/14789450.2018.1453362 · Cited by 11
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Zhang, C., & Yu, D. (2019) · Cell & Bioscience · doi:10.1186/s13578-019-0349-0 · Cited by 11
Joshi, L., Plastira, I., Bernhart, E. M., Reicher, H., Koshenov, Z., Graier, W. F., Vujić, N., Kratky, D., Rivera, R. R., Chun, J. J. M., et al. (2022) · Cells · doi:10.3390/cells11071071 · Cited by 11
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Li, B., He, D., Li, X., & Guo, X. (2022) · Ageing and Neurodegenerative Diseases · doi:10.20517/and.2022.14 · Cited by 11
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Xu, S.-Y., ZHANG, F., Tao, L., JIANG, Y., HUANG, T., Li, Y., Hu, Z., Yang, J., Hao, X., & Yuan, C. (2024) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(24)60601-1 · Cited by 10
Jia, Y., Tang, L., Yao, Y., Zhuo, L., Qu, D., Chen, X., Ji, Y., Tao, J., & Zhu, Y. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.993405 · Cited by 10
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Elguero, J., Liu, G., Tiemeyer, K. H., Bandyadka, S., Gandevia, H., Duro, L., Yan, Z., & McCall, K. (2023) · iScience · doi:10.1016/j.isci.2023.108052 · Cited by 10
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Wang, X., Jiang, S., Di, L., Li, S., Chen, H., Huang, P., Cao, T., Jin, W., & Huang, L. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115906 · Cited by 9
Shu, S., Jiang, M., Deng, X., Yue, W., Cao, X., Zhang, K., Wang, Z., He, H., Cui, J., Wang, Q., et al. (2023) · Aging Cell · doi:10.1111/acel.13947 · Cited by 9
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Oriá, R. B., Malva, J. O., Foley, P. L., Freitas, R. S., Bolick, D. T., & Guerrant, R. L. (2018) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2018.00358 · Cited by 9
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Li, X., Luo, L., Duan, P., Bi, Y., Meng, Y., Zhang, X., Feng, W., Jin, Z., Zuo, K., Zhao, X., et al. (2024) · Inflammation · doi:10.1007/s10753-024-02171-7 · Cited by 7
Biswas, D. D., Martin, R., Brown, L. N., Mockenhaupt, K., Gupta, A. S., Surace, M. J., Tharakan, A., Yester, J., Bhardwaj, R., Conrad, D. H., et al. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02527-6 · Cited by 7
Shen, J., Lai, W., Li, Z., Zhu, W., Bai, X., Yang, Z., Wang, Q., & Ji, J. (2024) · Inflammation Research · doi:10.1007/s00011-024-01913-5 · Cited by 7
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Zhu, X., Wang, X., Zhang, S., Li, X., Li, Z., Chen, X., Liu, X., Li, H., & Zhang, J. (2021) · Applied Sciences · doi:10.3390/app11178155 · Cited by 7
Arora, S., Critchley, G., Dekmak, A. S., Miesenböck, G., Kempf, A., & Ligoxygakis, P. (2025) · Brain Communications · doi:10.1093/braincomms/fcaf144 · Cited by 6
Bagh, M. B., Appu, A. P., Sadhukhan, T., Mondal, A., Plavelil, N., Raghavankutty, M., Supran, A. M., Sadhukhan, S., Liu, A., & Mukherjee, A. B. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.105641 · Cited by 7
Bello, E., Long, K. R., Iwama, S., Steer, J., Cooper, S., Alasoo, K., Kumasaka, N., Schwartzentruber, J., Panousis, N. I., & Bassett, A. R. (2026) · iScience · doi:10.1016/j.isci.2026.115688 · Cited by 7
Loskutova, E., Shah, K., Flitcroft, I., Setti, A., Butler, J. S., Nolan, Y. M., Paudel, N., & Loughman, J. (2019) · HRB Open Research · doi:10.12688/hrbopenres.12903.1 · Cited by 6
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Shi, Y., Hu, Y., Gan, Y., Mi, Z., Luo, S., Lei, J., Fang, Q., & Li, H. (2025) · Neuropharmacology · doi:10.1016/j.neuropharm.2025.110432 · Cited by 6
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Li, Y., Chang, J., Chen, X., Liu, J., & Zhao, L. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-230179 · Cited by 6
Yan, N., Wang, Z., Li, Z., Zheng, Y., Chang, N., Xu, K., Wang, Q., & Duan, X. (2023) · Biological Trace Element Research · doi:10.1007/s12011-023-04012-4 · Cited by 6
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Sato, T., Ishikawa, M., Izumi, Y., Shibata, N., Sato, K., Ohno‐Oishi, M., Tawarayama, H., Kunikata, H., Zorumski, C. F., & Nakazawa, T. (2025) · Biomedicines · doi:10.3390/biomedicines13071670 · Cited by 5
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Chen, Y., Wang, B., Wang, X., Wu, M., Yan, Z., Xu, X., & Yan, S. (2025) · Neuropsychology Review · doi:10.1007/s11065-025-09681-7 · Cited by 4
Asgharifar, S. F., & Heris, M. J. (2022) · Human Gene · doi:10.1016/j.humgen.2022.201057 · Cited by 4
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Anastasio, T. J. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190144 · Cited by 4
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Luz, I. S., Takaya, R., Ribeiro, D. G., Castro, M. S., & Fontes, W. (2024) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-50624-6_12 · Cited by 3
Chen, Y., Wu, G., Zhang, W., Zou, Z., Huang, L., Shi, H., Wang, Q. J., Chen, W., Luo, Z., Zhao, Z., et al. (2026) · Experimental & Molecular Medicine · doi:10.1038/s12276-026-01733-z · Cited by 3
Rejili, M., Al‐kuraishy, H. M., Shokr, M. M., & Batiha, G. E. (2026) · Biogerontology · doi:10.1007/s10522-026-10457-6 · Cited by 3
Gupta, A. K., Singh, S., & Singh, T. D. (2026) · Inflammopharmacology · doi:10.1007/s10787-026-02324-0 · Cited by 3
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Skliar, A. I., Torianyk, I., Осолодченко, Т. П., & Ponomarenko, S. V. (2020) · Pathologia · doi:10.14739/2310-1237.2020.3.221870 · Cited by 3
Manfready, R. A., Goetz, C. G., & Keshavarzian, A. (2022) · International review of neurobiology · doi:10.1016/bs.irn.2022.07.008 · Cited by 2
Borbolis, F., Ranti, D., Papadopoulou, M.-D., Dimopoulou, S., Malatras, A., Michalopoulos, I., & Syntichaki, P. (2023) · Biology · doi:10.3390/biology12020171 · Cited by 3
Halder, A. K., Moura, A. S., & Cordeiro, M. N. D. S. (2018) · Methods in pharmacology and toxicology · doi:10.1007/7653_2018_14 · Cited by 3
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Downs, B. W., Kushner, S. W., Bagchi, M., Blum, K., Badgaiyan, R. D., Chakraborty, S., & Bagchi, D. (2021) · Current Psychopharmacologye · doi:10.2174/2211556010666210122145526 · Cited by 3
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Oludipe, D. B., Du, X., Akter, S., Zhang, C., Mosley, R. L., Gendelman, H. E., & Sil, S. (2025) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a041640 · Cited by 3
Behera, P., Rangappa, N., Chandrashekar, M., Mishra, A., Chinnathambi, S., & Mishra, M. (2025) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2025.08.003 · Cited by 2
Duan, J., Zhang, S., Wang, B., Liu, Y., Liu, L., Liu, Y., Wu, J., & Cao, X. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2528269123 · Cited by 2
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Laß, J., & Trinh, J. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13550-7.00003-3 · Cited by 1
Wang, X., Bian, Y., & Chen, W.-G. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1504629 · Cited by 1
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Yang, W., & Wu, H. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-05716-z · Cited by 1
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Caspase-1 variant influencing CSF tau and FDG PET levels in non-demented elders from the ADNI cohort
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Liao, X., Zhu, W., Liao, X., Liu, W., Hou, Y., & Wan, J. (2024) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2024.1341901 · Cited by 1
Cui, Y., Ma, X., Wei, J., Chen, C., Shakir, N., Guirram, H., Dai, Z., Anderson, T. R., Ferguson, D., & Qiu, S. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-01471 · Cited by 2
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Wang, G., Yin, W., Shin, H., & Hou, X. S. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.27.012526
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Dardiotis, E., & Bogdanos, D. P. (2020) · Mediterranean Journal of Rheumatology · doi:10.31138/mjr.31.4.378
Adler, A. J. (2021) · Immunological Investigations · doi:10.1080/08820139.2021.1956723
Wang, X. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.736650668.793565579
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Nyúl‐Tóth, Á. (2018) · SZTE Repository of Dissertations (University of Szeged) · doi:10.14232/phd.9821
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Wang, J., Li, J., Wang, J., Sun, W., Fang, Q., Meng, M., Zhang, X., Jia, R., Li, X., Meng, X., et al. (2020) · Research Square · doi:10.21203/rs.3.rs-90903/v1
KUŞAT, T., & Emrah, S. U. R. (2023) · doi:10.59287/sbyc.582
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Borst, K., & Prinz, M. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-823848-6.00006-3
Charnolosome nanotheranostics in neurodegenerative diseases
Sharma, S. K. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-21752-4.00041-9
Badesso, S. (2024) · Deposito Adademico Digital Universidad De Navarra (University of Navarra) · doi:10.15581/10171/70194
Yang, Y., García-Cruzado, M., Zeng, H., Wang, X., Bachiller, S., Camprubí-Ferrer, L., Bahatyrevich-Kharitonik, B., Fernández‐Calle, R., & Deierborg, T. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.19.624204
Chang, R., Jia, H., Chen, Y., Loor, J. J., Xu, Q., Ma, L., Li, M., Shen, T., Li, X., Xu, C., et al. (2025) · Journal of Dairy Science · doi:10.3168/jds.2025-26828
Regulated cell death and inflammaging in neurodegenerative disorders
Liu, H., Wen, S., Gao, X., Wu, C., Lai, B., Zhu, J., & Kong, E. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-32852-7.00009-7
Wallach, T., Mossmann, Z. J., Szczepek, M., Wetzel, M., Machado, R. S. R., Raden, M., Miladi, M., Kleinau, G., Krüger, C., Dembny, P., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17088344
Wallach, T., Mossmann, Z. J., Szczepek, M., Wetzel, M., Machado, R. S. R., Raden, M., Miladi, M., Kleinau, G., Krüger, C., Dembny, P., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17088338
Wallach, T., Mossmann, Z. J., Szczepek, M., Wetzel, M., Machado, R. S. R., Raden, M., Miladi, M., Kleinau, G., Krüger, C., Dembny, P., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17088329
Wallach, T., Mossmann, Z. J., Szczepek, M., Wetzel, M., Machado, R. S. R., Raden, M., Miladi, M., Kleinau, G., Krüger, C., Dembny, P., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17088332
Wallach, T., Mossmann, Z. J., Szczepek, M., Wetzel, M., Machado, R. S. R., Raden, M., Miladi, M., Kleinau, G., Krüger, C., Dembny, P., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17088335
Wallach, T., Mossmann, Z. J., Szczepek, M., Wetzel, M., Machado, R. S. R., Raden, M., Miladi, M., Kleinau, G., Krüger, C., Dembny, P., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17088347
Iba, M., Kwon, S., Kim, C., Szabo, M. P., Horan-Portelance, L., Lopez-Ocasio, M. D., Dagur, P. K., Overk, C., Rissman, R. A., & Masliah, E. (2024) · Figshare · doi:10.6084/m9.figshare.25608801
Zhou, Q., Zhu, X., Li, Y., Yang, P., Wang, S., Ning, K., & Chen, S. (2022) · Figshare · doi:10.6084/m9.figshare.21192147
Wallach, T., Mossmann, Z. J., Szczepek, M., Wetzel, M., Machado, R. S. R., Raden, M., Miladi, M., Kleinau, G., Krüger, C., Dembny, P., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17088317
Metadata
- Authors
- Labzin, L. I., Heneka, M. T., & Latz, E.
- Affiliations
- MRC Laboratory of Molecular Biology (GB)
- University of Massachusetts Chan Medical School (US)
- Venue
- Annual Review of Medicine
- Publisher
- Annual Reviews
- Published
- 2018-01-29
- Volume
- 69
- Issue
- 1
- Pages
- 437-449
- ISSN
- 0066-4219 (ISSN-L)
- 1545-326X
- OpenAlex
- W2735217968
- Cited by
- 319
- References
- 80
- Citations by year
- 2026: 11 · 2025: 30 · 2024: 37 · 2023: 35 · 2022: 42 · 2021: 53 · 2020: 53 · 2019: 32 · 2018: 26
- FWCI
- 2.93
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annual Review of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Open Repository and Bibliography (University of Luxembourg) (submittedVersion, other-oa)
- DZNE Pub (submittedVersion)
- Funders
- EU Joint Programme – Neurodegenerative Disease Research
- Deutsche Forschungsgemeinschaft (SFB1089, SPP-1923)
- National Institutes of Health
- National Health and Medical Research Council
- National Heart, Lung, and Blood Institute (R01HL112661)
- Topics
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Inflammasome and immune disorders
- Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
- Keywords
- innate immunity, neurodegeneration, microglia, neuroinflammation, Alzheimer's disease, amyotrophic lateral sclerosis, Parkinson's disease, Huntington's disease, microglial activation, brain homeostasis, aging
- MeSH terms
- Alzheimer Disease, Amyotrophic Lateral Sclerosis, Humans, Huntington Disease, Immunity, Innate, Inflammation, Parkinson Disease, Microglia, Neurodegenerative Diseases
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