The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Bacterial Quorum Sensing During Infection
Open accessAbstract
Bacteria are highly interactive and possess an extraordinary repertoire of intercellular communication and social behaviors, including quorum sensing (QS). QS has been studied in detail at the molecular level, so mechanistic details are well understood in many species and are often involved in virulence. The use of different animal host models has demonstrated QS-dependent control of virulence determinants and virulence in several human pathogenic bacteria. QS also controls virulence in several plant pathogenic species. Despite the role QS plays in virulence during animal and plant laboratory-engineered infections, QS mutants are frequently isolated from natural infections, demonstrating that the function of QS during infection and its role in pathogenesis remain poorly understood and are fruitful areas for future research. We discuss the role of QS during infection in various organisms and highlight approaches to better understand QS during human infection. This is an important consideration in an era of growing antimicrobial resistance, when we are looking for new ways to target bacterial infections.
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Cites
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Contribution of Quorum Sensing to the Virulence of Pseudomonas aeruginosa in Burn Wound Infections
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Cited by
Infection microenvironment-related antibacterial nanotherapeutic strategies
Wang, Z., Liu, X., Duan, Y., & Huang, Y. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2021.121249 · Cited by 268
Pseudomonas aeruginosa: ecology, evolution, pathogenesis and antimicrobial susceptibility
Letizia, M., Diggle, S. P., & Whiteley, M. (2025) · Nature Reviews Microbiology · doi:10.1038/s41579-025-01193-8 · Cited by 231
Self-citationKin selection for cooperation in natural bacterial populations
Belcher, L. J., Dewar, A. E., Ghoul, M., & West, S. A. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2119070119 · Cited by 36
Metadata
- Authors
- Azimi, S., Klementiev, A. D., Whiteley, M., & Diggle, S. P.
- Venue
- Annual Review of Microbiology
- Publisher
- Annual Reviews
- Published
- 2020-09-08
- Volume
- 74
- Issue
- 1
- Pages
- 201-219
- ISSN
- 0066-4227 (ISSN-L)
- 1545-3251
- OpenAlex
- W3042576497
- Cited by
- 215
- References
- 5
- FWCI
- 2.02
- Type
- journal article
- Language
- en
- Open access
- green
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