The DOI matches its Crossref record; 140 of the 140 references it cites were found in a registry or an index.
Ecological Physiology of Diet and Digestive Systems
Open accessAbstract
The morphological and functional design of gastrointestinal tracts of many vertebrates and invertebrates can be explained largely by the interaction between diet chemical constituents and principles of economic design, both of which are embodied in chemical reactor models of gut function. Natural selection seems to have led to the expression of digestive features that approximately match digestive capacities with dietary loads while exhibiting relatively modest excess. Mechanisms explaining differences in hydrolase activity between populations and species include gene copy number variations and single-nucleotide polymorphisms. In many animals, both transcriptional adjustment and posttranscriptional adjustment mediate phenotypic flexibility in the expression of intestinal hydrolases and transporters in response to dietary signals. Digestive performance of animals depends also on their gastrointestinal microbiome. The microbiome seems to be characterized by large beta diversity among hosts and by a common core metagenome and seems to differ flexibly among animals with different diets.
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Cites
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Cited by
Intestinal luminal nitrogen metabolism: Role of the gut microbiota and consequences for the host
Davila, A.-M., Blachier, F., Gotteland, M., Andriamihaja, M., Benetti, P.-H., Sanz, Y., & Tomé, D. (2013) · Pharmacological Research · doi:10.1016/j.phrs.2012.11.005 · Cited by 548
Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila
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Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster
Miguel-Aliaga, I., Jasper, H., & Lemaitre, B. (2018) · Genetics · doi:10.1534/genetics.118.300224 · Cited by 491
Davila, A.-M., Blachier, F., Gotteland, M., Andriamihaja, M., Benetti, P.-H., Sanz, Y., & Tomé, D. (2013) · Pharmacological Research · doi:10.1016/j.phrs.2013.01.003 · Cited by 231
Gut microbiome modulates efficacy of immune checkpoint inhibitors
Yi, M., Yu, S., Qin, S., Liu, Q., Xu, H., Zhao, W., Chu, Q., & Wu, K. (2018) · Journal of Hematology & Oncology · doi:10.1186/s13045-018-0592-6 · Cited by 179
Metadata
- Authors
- Karasov, W. H., Martínez del Rio, C., & Caviedes-Vidal, E.
- Venue
- Annual Review of Physiology
- Publisher
- Annual Reviews
- Published
- 2011-03-17
- Volume
- 73
- Issue
- 1
- Pages
- 69-93
- ISSN
- 0066-4278 (ISSN-L)
- 1545-1585
- OpenAlex
- W2165510292
- Cited by
- 346
- References
- 140
- FWCI
- 1.99
- Type
- journal article
- Language
- en
- Open access
- green
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- Karasov, W. H., Martínez del Rio, C., & Caviedes-Vidal, E. (2011). Ecological Physiology of Diet and Digestive Systems. Annual Review of Physiology. https://doi.org/10.1146/annurev-physiol-012110-142152
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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