Lysosomal Acidification Mechanisms

Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology

Forgac, M. D. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2272 · Cited by 1,626

AN INTRODUCTION TO TRP CHANNELS

Ramsey, I. S., Delling, M., & Clapham, D. E. (2005) · Annual Review of Physiology · doi:10.1146/annurev.physiol.68.040204.100431 · Cited by 1,596

Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor

Pelegrı́n, P., & Surprenant, A. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601378 · Cited by 1,490

X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity

Dutzler, R., Campbell, E. B., Cadene, M., Chait, B. T., & MacKinnon, R. (2002) · Nature · doi:10.1038/415287a · Cited by 1,446

Loss of the ClC-7 Chloride Channel Leads to Osteopetrosis in Mice and Man

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Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms

Satyanarayana, A., & Kaldis, P. (2009) · Oncogene · doi:10.1038/onc.2009.170 · Cited by 800

NAADP mobilizes calcium from acidic organelles through two-pore channels

Calcraft, P. J., Ruas, M., Pan, Z., Cheng, X., Arredouani, A., Hao, X., Tang, J., Rietdorf, K., Teboul, L., Chuang, K.-T., et al. (2009) · Nature · doi:10.1038/nature08030 · Cited by 760

Gating the Selectivity Filter in ClC Chloride Channels

Dutzler, R., Campbell, E. B., & MacKinnon, R. (2003) · Science · doi:10.1126/science.1082708 · Cited by 727

The ABC protein turned chloride channel whose failure causes cystic fibrosis

Gadsby, D. C., Vergani, P., & Csanády, L. (2006) · Nature · doi:10.1038/nature04712 · Cited by 726

Mutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensorineural deafness

Karet, F. E., Finberg, K. E., Nelson, R. D., Nayır, A., Mocan, H. N., Sanjad, S. A., Rodríguez‐Soriano, J., Santos, F., Cremers, C. W. R. J., Pietro, A. D., et al. (1999) · Nature Genetics · doi:10.1038/5022 · Cited by 687

The chloride antiporter CLCN7 is a modifier of lysosome dysfunction in FIG4 and VAC14 mutants

Cao, X., Lenk, G. M., Mikušević, V., Mindell, J. A., & Meisler, M. H. (2023) · PLoS Genetics · doi:10.1371/journal.pgen.1010800 · Cited by 20

Proton-Coupled Photochromic Hemithioindigo: Toward Photoactivated Chemical Sensing and Imaging

Li, J., Ma, X., Wang, Y., Cheng, Y., Qin, Y., Zhai, J., & Xie, X. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.3c01504 · Cited by 19

Plk1 promotes renal tubulointerstitial fibrosis by targeting autophagy/lysosome axis

Du, Y., Shang, Y., Qian, Y., Guo, Y., Chen, S., Lin, X., Cao, W., Tang, X., Zhou, A., Huang, S., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-06093-4 · Cited by 19

Lysosome-oriented, dual-stage pH-responsive polymeric micelles for β-lapachone delivery

Zhou, Y., Dong, Y., Huang, G., Wang, Y., Huang, X., Zhang, F., Boothman, D. A., Gao, J., & Liang, W. P. (2016) · Journal of Materials Chemistry B · doi:10.1039/c6tb02049f · Cited by 19

Remission of lymphoblastic leukaemia in an intravascular fluidic environment by pliable drug carrier with a sliding target ligand

Jang, D., Lee, Y. M., Lee, J., Doh, J., & Kim, W. J. (2017) · Scientific Reports · doi:10.1038/srep40739 · Cited by 19

Monitoring ATPase induced pH changes in single proteoliposomes with the lipid-coupled fluorophore Oregon Green 488

Schwamborn, M., Schumacher, J., Sibold, J., Teiwes, N. K., & Steinem, C. (2017) · The Analyst · doi:10.1039/c7an00215g · Cited by 19

Endoplasmic Reticulum Stress and Autophagy

Kabir, M. F., Kim, H., & Chae, H. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.81381 · Cited by 21

BK channel inhibition by strong extracellular acidification

Zhou, Y., Xia, X., & Lingle, C. J. (2018) · eLife · doi:10.7554/elife.38060 · Cited by 18

Enhanced lysosome escape mediated by 1,2-dicarboxylic-cyclohexene anhydride-modified poly-l-lysine dendrimer as a gene delivery system

Shen, J., Chen, J., Ma, J., Fan, L.-L., Zhang, X., Yue, T., Yan, Y., & Zhang, Y. (2020) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2019.12.001 · Cited by 19

How do cells optimize luminal environments of endosomes/lysosomes for efficient inflammatory responses?

Kobayashi, T., Tanaka, T., & Toyama‐Sorimachi, N. (2013) · The Journal of Biochemistry · doi:10.1093/jb/mvt099 · Cited by 21

Methotrexate-coupled nanoparticles and magnetic nanochemothermia for the relapse-free treatment of T24 bladder tumors

Stapf, M., Teichgräber, U. K.-M., & Hilger, I. (2017) · International Journal of Nanomedicine · doi:10.2147/ijn.s120969 · Cited by 18

Swainsonine promotes apoptosis by impairing lysosomal function and inhibiting autophagic degradation in rat primary renal tubular epithelial cells

Wang, S., Guo, R., Su, Y., Yang, C., Guo, Y., Tan, C., & Zhao, B. (2020) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2020.109319 · Cited by 18

Porcine Deltacoronavirus (PDCoV) Entry into PK-15 Cells by Caveolae-Mediated Endocytosis

Li, S., Xiao, D., Zhao, Y., Zhang, L., Chen, R., Liu, W., Wen, Y., Liao, Y., Wen, Y., Wu, R. J., et al. (2022) · Viruses · doi:10.3390/v14030496 · Cited by 18

Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model

Chin, M. Y., Ang, K.-H., Davies, J. L., Alquézar, C., Garda, V. G., Rooney, B., Leng, K., Kampmann, M., Arkin, M. R., & Kao, A. W. (2022) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.1c00804 · Cited by 17

Physiological Overview of the Potential Link between the UPS and Ca2+ Signaling

Lee, D., & Hong, J. H. (2022) · Antioxidants · doi:10.3390/antiox11050997 · Cited by 19

A pyrene-derived ratiometric fluorescent probe for pH monitoring in cells and zebrafish based on monomer-excimer emission

Cui, J. W., Nie, H., Liang, X., Bai, J., & Zhang, X. (2022) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2022.120325 · Cited by 18

Kaposi’s sarcoma-associated herpesvirus (KSHV) LANA prevents KSHV episomes from degradation

Nakajima, K.-I., Inagaki, T., Espera, J. M., & Izumiya, Y. (2024) · Journal of Virology · doi:10.1128/jvi.01268-23 · Cited by 18

High glucose disrupts autophagy lysosomal pathway in gingival epithelial cells via ATP6V0C

Huang, X., Kuang, S., Shen, Z., Liang, M., & Lin, Z. (2019) · Journal of Periodontology · doi:10.1002/jper.19-0262 · Cited by 18

Oxygen Tension Regulates Lysosomal Activation and Receptor Tyrosine Kinase Degradation

Hong, J., Wuest, T. R., Min, Y., & Lin, P. C. (2019) · Cancers · doi:10.3390/cancers11111653 · Cited by 18

Protein-aggregating ability of different protoporphyrin-IX nanostructures is dependent on their oxidation and protein-binding capacity

Maitra, D., Pinsky, B. M., Soherawardy, A., Zheng, H., Banerjee, R. V., & Omary, M. B. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100778 · Cited by 19

Strategies and challenges for non-viral delivery of non-coding RNAs to the heart

Vilaça, A., Windt, L. J. D., Fernandes, H., & Ferreira, L. (2022) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2022.10.002 · Cited by 20

A Mathematical Model of Lysosomal Ion Homeostasis Points to Differential Effects of Cl− Transport in Ca2+ Dynamics

Astaburuaga-García, R., Quintanar-Haro, O. D., Stauber, T., & Relógio, A. (2019) · Cells · doi:10.3390/cells8101263 · Cited by 20

A “ CPApoptosis ” nano-actuator switches immune-off solid tumors to immune-on for fueling T-cell- based immunotherapy

Luo, Y., Wang, Y., Liu, B., Liu, Y., Zhang, W., Chen, S., Rong, X., Xu, L., Du, Q., Liu, J., et al. (2025) · Theranostics · doi:10.7150/thno.105867 · Cited by 17

Photoluminescent nanosensors for intracellular detection

Kerr, C. A., & de la Rica, R. (2015) · Analytical Methods · doi:10.1039/c5ay00489f · Cited by 17

The impact of assay recovery on the apparent permeability, a function of lysosomal trapping

Bednarczyk, D., & Sanghvi, M. V. (2019) · Xenobiotica · doi:10.1080/00498254.2019.1691284 · Cited by 17

Stochastics of degradation: the autophagic-lysosomal system of the cell

Kudriaeva, A. A., Av, S., & Belogurov, A. A. (2020) · Acta Naturae · doi:10.32607/actanaturae.10936 · Cited by 20

Visible light responsive photoacids for subcellular pH and temperature correlated fluorescence sensing

Cheng, Y., Ma, X., Zhai, J., & Xie, X. (2023) · Chemical Communications · doi:10.1039/d2cc06816h · Cited by 17

Chitosan particle-emulsion complex adjuvants: The effect of particle distribution on the immune intensity and response type

Wu, N., Chen, Q., Zou, Y., Miao, C., Ma, G., & Wu, J. (2023) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2023.120673 · Cited by 17

Organic Acid Accumulation and Associated Dynamic Changes in Enzyme Activity and Gene Expression during Fruit Development and Ripening of Common Loquat and Its Interspecific Hybrid

Deng, H., Li, X., Wang, Y., Ma, Q., Zeng, Y., Xiang, Y., Chen, M., Zhang, H., Xia, H., Liang, D., et al. (2023) · Foods · doi:10.3390/foods12050911 · Cited by 17

Critical role of ROCK1 in AD pathogenesis via controlling lysosomal biogenesis and acidification

Song, C., Huang, W., Zhang, P., Shi, J., Yu, T. Y., Wang, J., Hu, Y., Zhao, L., Zhang, R., Wang, G., et al. (2024) · Translational Neurodegeneration · doi:10.1186/s40035-024-00442-9 · Cited by 19

A novel derivative of riccardin D induces cell death through lysosomal rupture in vitro and inhibits tumor growth in vivo

Wang, Y., Wang, L., Hu, Z., Ji, Y., Lin, Z., Yuan, H., Ji, M., & Lou, H. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.10.042 · Cited by 17

Formation of Tubulovesicular Carriers from Endosomes and Their Fusion to the trans-Golgi Network

Hierro, A., Gershlick, D. C., Rojas, A. L., & Bonifacino, J. S. (2015) · International review of cytology · doi:10.1016/bs.ircmb.2015.05.005 · Cited by 19

Intermolecular G-Quadruplex Induces Hyaluronic Acid–DNA Superpolymers Causing Cancer Cell Swelling, Blebbing, and Death

Beals, N., Model, M. A., Worden, M., Hegmann, T., & Basu, S. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b16983 · Cited by 17

Thermosensitive Biodegradable Copper Sulfide Nanoparticles for Real-Time Multispectral Optoacoustic Tomography

Shi, S., Wen, X., Li, T., Wen, X., Cao, Q., Liu, X., Liu, Y., Pagel, M. D., & Li, C. (2019) · ACS Applied Bio Materials · doi:10.1021/acsabm.9b00133 · Cited by 17

Downregulation of Lysosomal Acid Ceramidase Mediates HMGB1-Induced Migration and Proliferation of Mouse Coronary Arterial Myocytes

Yuan, X., Bhat, O. M., Lohner, H., Zhang, Y., & Li, P. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00111 · Cited by 17

Serum lipoprotein–derived fatty acids regulate hypoxia-inducible factor

Shao, W., Hwang, J., Liu, C., Mukhopadhyay, D., Zhao, S., Shen, M., Alpergin, E. S. S., Wolfgang, M. J., Farber, S. A., & Espenshade, P. J. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra120.015238 · Cited by 17

Near-infrared ratiometric fluorescence imaging of lysosomal polarity in live cells and in vivo

Chao, X., Hu, Y., Liu, R., Huang, D., & Zhang, Y. (2021) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2021.130397 · Cited by 17

Lighting up Individual Organelles With Fluorescent Carbon Dots

Liu, H., Guo, J., Aryee, A. A., Hua, L., Sun, Y., Li, Z., Liu, J., & Tang, W. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.784851 · Cited by 17

Reduced mitochondria membrane potential and lysosomal acidification are associated with decreased oligomeric Aβ degradation induced by hyperglycemia: A study of mixed glia cultures

Huang, Y., Hsu, S.-M., Shie, F., Shiao, Y., Chao, L.-J., Chen, H., Yao, H.-H., Chien, M. A., Lin, C., & Tsay, H.-J. (2022) · PLoS ONE · doi:10.1371/journal.pone.0260966 · Cited by 17

Development of Thermo- and pH-Sensitive Liposomal Magnetic Carriers for New Potential Antitumor Thienopyridine Derivatives

Ribeiro, B. C., Alvarez, C. A. R., Alves, B. C., Rodrigues, J. D. S., Queiroz, M. J. R. P., Almeida, B. G., Pires, A. L., Pereira, A. M., Araújo, J. P., Coutinho, P. J. G., et al. (2022) · Materials · doi:10.3390/ma15051737 · Cited by 17

Intelligent Nano‐Cage for Precision Delivery of CRISPR‐Cas9 and ACC Inhibitors to Enhance Antitumor Cascade Therapy Through Lipid Metabolism Disruption

Zhao, W., La, Z., Guo, J., Xu, Q., Zhang, M., Liu, H., Ren, C., Zhao, Y., Wang, J., Peng, Q., et al. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202418090 · Cited by 17

Two‐Color Single‐Molecule Blinking Ratiometricity: A Functional Super‐Resolution Imaging Approach for Resolving Lysosomal pH and Dynamics

Qiao, Q., Yin, W., Wu, X., Wu, S., Ruan, Y., Xu, N., Li, J., Wu, Z., Liu, X., & Xu, Z. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202503916 · Cited by 16

Two-pore channels: going with the flows

Morgan, A. J., Martucci, L. L., Davis, L. C., & Galione, A. (2022) · Biochemical Society Transactions · doi:10.1042/bst20220229 · Cited by 16

The presence of blastocyst within the uteri facilitates lumenal epithelium transformation for implantation via upregulating lysosome proteostasis activity

Wang, P., Du, S., Guo, C., Ni, Z., Huang, Z., Deng, N., Bao, H., Deng, W., Lu, J., Kong, S., et al. (2023) · Autophagy · doi:10.1080/15548627.2023.2247747 · Cited by 16

Clinical biomarkers for Lewy body diseases

Abdelmoaty, M. M., Lu, E., Kadry, R., Foster, E. G., Bhattarai, S., Mosley, R. L., & Gendelman, H. E. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01152-x · Cited by 17

Gain-of-function variants in CLCN7 cause hypopigmentation and lysosomal storage disease

Polovitskaya, M. M., Rana, T., Ullrich, K., Murko, S., Bierhals, T., Vogt, G., Stauber, T., Kubisch, C., Santer, R., & Jentsch, T. J. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.107437 · Cited by 16

Methods for monitoring lysosomal morphology

Kilpatrick, B. S., Eden, E. R., Hockey, L. N., Futter, C. E., & Patel, S. (2015) · Methods in cell biology · doi:10.1016/bs.mcb.2014.10.018 · Cited by 17

Camptothecin delivery into hepatoma cell line by galactose-appended fluorescent drug delivery system

Dongbang, S., Jeon, H. M., Lee, M. H., Shin, W. S., Kwon, J. K., Kang, C., & Kim, J. S. (2014) · RSC Advances · doi:10.1039/c4ra02588a · Cited by 16

High perfluorooctanoic acid exposure induces autophagy blockage and disturbs intracellular vesicle fusion in the liver

Yan, S., Zhang, H., Guo, X., Wang, J., & Dai, J. (2016) · Archives of Toxicology · doi:10.1007/s00204-016-1675-1 · Cited by 16

Acrosomal alkalinization occurs during human sperm capacitation

Carrasquel‐Martínez, G., Aldana, A., Carneiro, J., Treviño, C. L., & Darszon, A. (2022) · Molecular Human Reproduction · doi:10.1093/molehr/gaac005 · Cited by 17

Not just protons: Chloride also activates lysosomal acidic hydrolases

Feng, X., Liu, S., & Xu, H. (2023) · The Journal of Cell Biology · doi:10.1083/jcb.202305007 · Cited by 16

A tale of two CLCs: biophysical insights toward understanding ClC‐5 and ClC‐7 function in endosomes and lysosomes

Zifarelli, G. (2015) · The Journal of Physiology · doi:10.1113/jp270604 · Cited by 16

Identification of Sidt2 as a lysosomal cation‐conducting protein

Beck, A., Fecher‐Trost, C., Wolske, K., Philipp, S. E., Flockerzi, V., & Wissenbach, U. (2016) · FEBS Letters · doi:10.1002/1873-3468.12528 · Cited by 17

Studies on the stability of the anticancer-active [N,N′-bis(salicylidene)-1,2-phenylenediamine]chloridoiron(III) complex under pharmacological-like conditions

Deeb, S. E., Ma, B. N., Baecker, D., & Gust, R. (2018) · Inorganica Chimica Acta · doi:10.1016/j.ica.2018.12.002 · Cited by 16

Fate of Carbon Nanotubes Locally Implanted in Mice Evaluated by Near-Infrared Fluorescence Imaging: Implications for Tissue Regeneration

Hirata, E., Yudasaka, M., Ushijima, N., Sakaguchi, N., Maeda, Y., Tanaka, T., Kataura, H., & Yokoyama, A. (2019) · ACS Applied Nano Materials · doi:10.1021/acsanm.8b02267 · Cited by 17

High-fidelity imaging of lysosomal enzyme through in situ ordered assembly of small molecular fluorescent probes

Lou, X., Ren, T., Chen, H., Huan, S., Yuan, L., & Zhang, X. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121657 · Cited by 15

Endogenous formaldehyde responsive fluorescent probe for bioimaging

Yi, N.-B., Hu, X., Wang, F., Chen, S.-Y., Xu, X., Li, X., Wang, H., Sun, T., Qiao, Z., & Cheng, D. (2023) · Nano Research · doi:10.1007/s12274-023-5766-z · Cited by 15

SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification

Zhu, L., Xia, X., Li, G., Zhu, C., Li, Q., Wang, B., Shi, N.-X., Lei, Z., Yang, S., Zhang, Z., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112910 · Cited by 15

Impaired lysosomal acidity maintenance in acid lipase-deficient cells leads to defective autophagy

Moriwaki, T., Terawaki, S., & Otomo, T. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.105743 · Cited by 15

MYO18B promotes lysosomal exocytosis by facilitating focal adhesion maturation

Ren, W., Kawahara, R., Suzuki, K. G. N., Dipta, P., Yang, G., Thaysen‐Andersen, M., & Fujita, M. (2024) · The Journal of Cell Biology · doi:10.1083/jcb.202407068 · Cited by 15

Immunostimulatory Hydrogel with Synergistic Blockage of Glutamine Metabolism and Chemodynamic Therapy for Postoperative Management of Glioblastoma

Guo, Y., Jiang, T., Liang, S., Wang, A., Li, J., Jia, Y., Li, Q., Yin, J., Bai, S., & Li, J. (2025) · Advanced Science · doi:10.1002/advs.202412507 · Cited by 15

pH-Sensitive fluorophores from locked GFP chromophores by a non-alternant analogue of the photochemical meta effect

Olsen, S., Baranov, M. S., Baleeva, N. S., Antonova, M. M., Johnson, K. A., & Solntsev, K. M. (2016) · Physical Chemistry Chemical Physics · doi:10.1039/c6cp02423h · Cited by 15

Lysosomes in nutrient signalling: A focus on pancreatic β‐cells

Mészáros, G., Pasquier, A., Vivot, K., Goginashvili, A., & Ricci, R. (2018) · Diabetes Obesity and Metabolism · doi:10.1111/dom.13389 · Cited by 18

An mTORC1/2 kinase inhibitor enhances the cytotoxicity of gemtuzumab ozogamicin by activation of lysosomal function

Maimaitili, Y., Inase, A., Miyata, Y., Kitao, A., Mizutani, Y., Kakiuchi, S., Shimono, Y., Saito, Y., Sonoki, T., Minami, H., et al. (2018) · Leukemia Research · doi:10.1016/j.leukres.2018.09.017 · Cited by 15

Aptamers with Self-Loading Drug Payload and pH-Controlled Drug Release for Targeted Chemotherapy

Zeng, Z., Qi, J., Wan, Q., & Zu, Y. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13081221 · Cited by 15

A Review of APOE Genotype-Dependent Autophagic Flux Regulation in Alzheimer’s Disease

Chen, H., Chen, F., Zhang, M., Chen, Y., Cui, L., & Liang, C. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210602 · Cited by 15

Combination of mitochondria impairment and inflammation blockade to combat metastasis

Yi, X., Yan, Y., Li, L., Zhou, R., Shen, X., & Huang, Y. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.12.015 · Cited by 15

Fully Automated Computational Approach for Precisely Measuring Organelle Acidification with Optical pH Sensors

Chandra, A., Prasad, S., Alemanno, F., Luca, M. D., Rizzo, R., Romanò, R., Gigli, G., Bucci, C., Adriano Barra, A., & del Mercato, L. L. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c00389 · Cited by 14

Ligand Accessibility and Bioactivity of a Hormone–Dendrimer Conjugate Depend on pH and pH History

Kim, S. H., Madak‐Erdogan, Z., Bae, S. C., Carlson, K. E., Mayne, C. G., Granick, S., Katzenellenbogen, B. S., & Katzenellenbogen, J. A. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b05952 · Cited by 15

Targeting the sAC-Dependent cAMP Pool to Prevent SARS-Cov-2 Infection

Aslam, M., & Ladilov, Y. V. (2020) · Cells · doi:10.3390/cells9091962 · Cited by 15

Nonreceptor tyrosine kinase ABL1 regulates lysosomal acidification by phosphorylating the ATP6V1B2 subunit of the vacuolar-type H + -ATPase

Song, C., Dong, Q., Yao, Y., Cui, Y. R., Zhang, C., Lin, L., Zhu, L., Hu, Y., Liu, H., Jin, Y., et al. (2025) · Autophagy · doi:10.1080/15548627.2024.2448913 · Cited by 14

TMEM175 does not function as a proton-selective ion channel to prevent lysosomal over-acidification

Riederer, E. A., Mikušević, V., Tang, T., Martin, L., Mindell, J. A., & Ren, D. (2025) · The Journal of Cell Biology · doi:10.1083/jcb.202501145 · Cited by 16

A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body

Murakawa, T., Nakamura, T., Kawaguchi, K., Murayama, F., Zhao, N., Stasevich, T. J., Kimurâ, H., & Fujita, N. (2022) · Development · doi:10.1242/dev.200243 · Cited by 20

Parkin-dependent mitophagy occurs via proteasome-dependent steps sequentially targeting separate mitochondrial sub-compartments for autophagy

Lechado‐Terradas, A., Schepers, S., Zittlau, K. I., Sharma, K., Ok, O., Fitzgerald, J. C., Geimer, S., Westermann, B., Maček, B., & Kahle, P. J. (2022) · Autophagy Reports · doi:10.1080/27694127.2022.2143214 · Cited by 17

Bone regeneration strategies based on organelle homeostasis of mesenchymal stem cells

Xin, L., Wen, Y., Song, J., Chen, T., & Zhai, Q. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1151691 · Cited by 14

Human cytomegalovirus degrades DMXL1 to inhibit autophagy, lysosomal acidification, and viral assembly

Li, H., Fletcher-Etherington, A., Hunter, L. M., Keshri, S., Fielding, C. A., Nightingale, K., Ravenhill, B. J., Nobre, L., Potts, M., Antrobus, R., et al. (2024) · Cell Host & Microbe · doi:10.1016/j.chom.2024.02.013 · Cited by 16

Plasma exosomes impair microglial degradation of α‐synuclein through V‐ATPase subunit V1G1

Li, Y., Wang, Y., Kou, L., Yin, S., Chi, X., Sun, Y., Wu, J., Jin, Z., Zhou, Q., Zou, W., et al. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14738 · Cited by 14

Cell biology in China: Focusing on the lysosome

Yang, C., & Wang, X. (2017) · Traffic · doi:10.1111/tra.12483 · Cited by 14

An Expandable Mechanopharmaceutical Device (1): Measuring the Cargo Capacity of Macrophages in a Living Organism

Rzeczycki, P., Woldemichael, T., Willmer, A. R., Murashov, M. D., Baik, J., Keswani, R. K., Yoon, G. S., Stringer, K. A., Rodríguez‐Hornedo, N., & Rosania, G. R. (2018) · Pharmaceutical Research · doi:10.1007/s11095-018-2539-6 · Cited by 14

Degradation Products of Amyloid Protein: Are They The Culprits?

Zaretsky, D. V., & Zaretskaia, M. V. (2020) · Current Alzheimer Research · doi:10.2174/1567205017666201203142103 · Cited by 14

ClCd and ClCf act redundantly at the trans -Golgi network/early endosome and prevent acidification of the Golgi stack

Scholl, S., Hillmer, S., Krebs, M., & Schumacher, K. (2021) · Journal of Cell Science · doi:10.1242/jcs.258807 · Cited by 14

Recent advance in dual-functional luminescent probes for reactive species and common biological ions

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