Lysosomal Acidification Mechanisms

Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology

Forgac, M. D. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2272 · Cited by 1,626

AN INTRODUCTION TO TRP CHANNELS

Ramsey, I. S., Delling, M., & Clapham, D. E. (2005) · Annual Review of Physiology · doi:10.1146/annurev.physiol.68.040204.100431 · Cited by 1,596

Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor

Pelegrı́n, P., & Surprenant, A. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601378 · Cited by 1,490

X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity

Dutzler, R., Campbell, E. B., Cadene, M., Chait, B. T., & MacKinnon, R. (2002) · Nature · doi:10.1038/415287a · Cited by 1,446

Loss of the ClC-7 Chloride Channel Leads to Osteopetrosis in Mice and Man

Kornak, U., Kasper, D., Bösl, M. R., Kaiser, E., Schweizer, M., Schulz, A., Friedrich, W., Delling, G., & Jentsch, T. J. (2001) · Cell · doi:10.1016/s0092-8674(01)00206-9 · Cited by 995

Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms

Satyanarayana, A., & Kaldis, P. (2009) · Oncogene · doi:10.1038/onc.2009.170 · Cited by 800

NAADP mobilizes calcium from acidic organelles through two-pore channels

Calcraft, P. J., Ruas, M., Pan, Z., Cheng, X., Arredouani, A., Hao, X., Tang, J., Rietdorf, K., Teboul, L., Chuang, K.-T., et al. (2009) · Nature · doi:10.1038/nature08030 · Cited by 760

Gating the Selectivity Filter in ClC Chloride Channels

Dutzler, R., Campbell, E. B., & MacKinnon, R. (2003) · Science · doi:10.1126/science.1082708 · Cited by 727

The ABC protein turned chloride channel whose failure causes cystic fibrosis

Gadsby, D. C., Vergani, P., & Csanády, L. (2006) · Nature · doi:10.1038/nature04712 · Cited by 726

Mutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensorineural deafness

Karet, F. E., Finberg, K. E., Nelson, R. D., Nayır, A., Mocan, H. N., Sanjad, S. A., Rodríguez‐Soriano, J., Santos, F., Cremers, C. W. R. J., Pietro, A. D., et al. (1999) · Nature Genetics · doi:10.1038/5022 · Cited by 687

The interdependent transport of yeast vacuole Ca2+ and H+ and the role of phosphatidylinositol 3,5-bisphosphate

Zhang, C., Feng, Y., Balutowski, A., Miner, G. E., Rivera‐Kohr, D. A., Hrabak, M. R., Sullivan, K. D., Guo, A., Calderin, J. D., & Fratti, R. A. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102672 · Cited by 11

Synthetic Ionizable Colloidal Drug Aggregates Enable Endosomal Disruption

Donders, E. N., Slaughter, K. V., Dank, C., Ganesh, A. N., Shoichet, B. K., Lautens, M., & Shoichet, M. S. (2023) · Advanced Science · doi:10.1002/advs.202300311 · Cited by 12

A Lysosome-Targeted Near-Infrared Fluorescent Probe with Excellent Water Solubility for Surgery Navigation in Breast Cancer

Wu, Y., Chen, Z., Shen, D., He, Z., Lv, J., Li, H., Yang, M., Tan, J., Yuan, J., Gao, J., et al. (2023) · ACS Omega · doi:10.1021/acsomega.3c00601 · Cited by 13

Loss of Prom1 impairs autophagy and promotes epithelial‐mesenchymal transition in mouse retinal pigment epithelial cells

Bhattacharya, S., Yin, J., Huo, W., & Chaum, E. (2023) · Journal of Cellular Physiology · doi:10.1002/jcp.31094 · Cited by 13

Lysosome electrophysiology

Zhong, X. Z., & Dong, X. (2015) · Methods in cell biology · doi:10.1016/bs.mcb.2014.10.022 · Cited by 12

P2X4 receptor re‐sensitization depends on a protonation/deprotonation cycle mediated by receptor internalization and recycling

Fois, G., Föhr, K. J., Kling, C., Fauler, M., Wittekindt, O. H., Dietl, P., & Frick, M. (2018) · The Journal of Physiology · doi:10.1113/jp275448 · Cited by 13

Age-related dysfunction of the autophago-lysosomal pathway in human endothelial cells

Mai, S., Brehm, N., Auburger, G. W. J., Bereiter‐Hahn, J., & Jendrach, M. (2019) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-019-02288-x · Cited by 13

A Doxorubicin-Glucuronide Prodrug Released from Nanogels Activated by High-Intensity Focused Ultrasound Liberated β-Glucuronidase

Besse, H. C., Chen, Y., Scheeren, H. W., Metselaar, J. M., Lammers, T., MOONEN, C. T. W., Hennink, W. E., & Deckers, R. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12060536 · Cited by 13

The physiological role of the unfolded protein response in the nervous system

Wu, S., & Lin, W. (2024) · Neural Regeneration Research · doi:10.4103/1673-5374.393105 · Cited by 16

NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA

Zhan, Y., Deng, C., Tang, L., Li, S., Xu, T., Wei, X., Zhang, X., Zheng, C., Deng, L., Shao, C., et al. (2025) · Advanced Science · doi:10.1002/advs.202502931 · Cited by 12

Bioinformatics analysis of differentially expressed genes and identification of an miRNA–mRNA network associated with entorhinal cortex and hippocampus in Alzheimer’s disease

Li, H., Zou, L., Shi, J., & Han, X. (2021) · Hereditas · doi:10.1186/s41065-021-00190-0 · Cited by 12

Syndromic Deafness Gene ATP6V1B2 Controls Degeneration of Spiral Ganglion Neurons Through Modulating Proton Flux

Qiu, S., Zhao, W., Gao, X., Li, D., Wang, W., Gao, B., Han, W., Yang, S., Dai, P., Cao, P., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.742714 · Cited by 12

Microenvironmental Impact on InP/ZnS-Based Quantum Dots in In Vitro Models and in Living Cells: Spectrally- and Time-Resolved Luminescence Analysis

Litvinov, I. K., Salova, A. V., Aksenov, N., Корнилова, Е. С., & Belyaeva, T. N. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032699 · Cited by 12

Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe Podocytopathy

Vöing, K., Michgehl, U., Mertens, N. D., Picciotto, C., Maywald, M.-L., Goretzko, J., Waimann, S., Gilhaus, K., Rogg, M., Schell, C., et al. (2023) · Journal of the American Society of Nephrology · doi:10.1681/asn.0000000000000126 · Cited by 11

Characterization of the role of TMEM175 in an in vitro lysosomal H+ fluxes model

Yang, C., Tian, F., Hu, M. Y., Kang, C., Ping, M., Liu, Y., Hu, M., Xu, H., Ye, Y., Gao, Z., et al. (2023) · FEBS Journal · doi:10.1111/febs.16814 · Cited by 13

TAZ deficiency impairs the autophagy-lysosomal pathway through NRF2 dysregulation and lysosomal dysfunction

Kim, H. K., Jeong, H., Jeong, M. G., Won, H. Y., Lee, G., Bae, S. H., Nam, M., Lee, S. H., Hwang, G., & Hwang, E. S. (2024) · International Journal of Biological Sciences · doi:10.7150/ijbs.88897 · Cited by 12

Inhibition of cathepsin L ameliorates inflammation through the A20/NF-κB pathway in endotoxin-induced acute lung injury

Yang, S., Chen, K., Yu, J., Jin, Z., Zhang, M., Li, Z., Yu, Y., Xuan, N., Tian, B., Li, N., et al. (2024) · iScience · doi:10.1016/j.isci.2024.111024 · Cited by 13

RpH-ILV: Probe for lysosomal pH and acute LLOMe-induced membrane permeabilization in cell lines and Drosophila

Cheetham‐Wilkinson, I. J., Sivalingam, B., Flitton, C., Flottmann, F., Vehling, L., Drechsler, M., Stojchevska, M., Raimondi, A., Paululat, A., Fröhlich, F., et al. (2025) · Science Advances · doi:10.1126/sciadv.adr7325 · Cited by 13

Autophagy flux inhibition mediated by lysosomal dysfunction participates in the cadmium exposure‐induced cardiotoxicity in swine

Zhao, X., Xu, S., Yao, Y., Li, X., & Xu, S. (2022) · BioFactors · doi:10.1002/biof.1834 · Cited by 12

Impaired Autophagic Clearance with a Gain-of-Function Variant of the Lysosomal Cl−/H+ Exchanger ClC-7

Bose, S., de Heus, C., Kennedy, M. E., Wang, F., Jentsch, T. J., Klumperman, J., & Stauber, T. (2023) · Biomolecules · doi:10.3390/biom13121799 · Cited by 13

Thoughts on a very acidic symbiosome

Tang, B. L. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00816 · Cited by 12

Evaluation of Drosophila Metabolic Labeling Strategies for in Vivo Quantitative Proteomic Analyses with Applications to Early Pupa Formation and Amino Acid Starvation

Chang, Y.-C., Tang, H.-W., Liang, S., Pu, T.-H., Meng, T., Khoo, K., & Chen, G. (2013) · Journal of Proteome Research · doi:10.1021/pr301168x · Cited by 12

Dual Detection of Nucleolytic and Proteolytic Markers of Lysosomal Cell Death: DNase II-Type Breaks and Cathepsin D

Minchew, C. L., & Didenko, V. V. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6759-9_16 · Cited by 12

Can endolysosomal deacidification and inhibition of autophagy prevent severe COVID-19?

Morris, G., Athan, E., Walder, K. R., Bortolasci, C. C., O'Neil, A. E., Marx, W., Berk, M., Carvalho, A. F., Maes, M. H. J., & Puri, B. K. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118541 · Cited by 12

Potential Antiviral Strategy Exploiting Dependence of SARS-CoV-2 Replication on Lysosome-Based Pathway

Lan, Y., He, W., Wang, G., Wang, Z., Chen, Y., Gao, F., & Song, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23116188 · Cited by 12

Triggered Release Enhances the Cytotoxicity of Stable Colloidal Drug Aggregates

Donders, E. N., Ganesh, A. N., Torosyan, H., Lak, P., Shoichet, B. K., & Shoichet, M. S. (2019) · ACS Chemical Biology · doi:10.1021/acschembio.9b00247 · Cited by 12

Modulation of lysosomal function as a therapeutic approach for coronaviral infectionsPreprint

Liu, Y., Lear, T., Larsen, M. B., Lin, B., Cao, Q. N., Alfaras, I., Kennerdell, J. R., Salminen, L., Camarco, D. P., Lockwood, K. C., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-419305/v1 · Cited by 12

DNA nanodevices detect an acidic nanolayer on the lysosomal surface

Zhang, Y., Meiqin, H., Meng, Y., Wang, X., Huang, F., Li, P., Zhuo, Y., Chen, D., Wang, Z., Zhang, Q., et al. (2026) · Nature Cell Biology · doi:10.1038/s41556-025-01855-y · Cited by 12

Exploring lysosomal biology: current approaches and methods

Yin, Q., & Yang, C. (2024) · Biophysics Reports · doi:10.52601/bpr.2023.230028 · Cited by 11

Advancements on the impact of hydroxychloroquine in systemic lupus erythematosus

Peng-Cheng, L., Meng-Na, L., Li, J., Shu-Jiao, Y., & Wu, R. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e30393 · Cited by 14

Toward understanding the cellular control of vertebrate mineralization: The potential role of mitochondria

Shapiro, I. M., Risbud, M. V., & Landis, W. J. (2024) · Bone · doi:10.1016/j.bone.2024.117112 · Cited by 12

Autophagy Dysfunction and Neurodegeneration: Where Does It Go Wrong?

Oettinger, D., & Yamamoto, A. (2025) · Journal of Molecular Biology · doi:10.1016/j.jmb.2025.169219 · Cited by 10

WO 3 /Pt nanoparticles promote light-induced lipid peroxidation and lysosomal instability within tumor cells

Clark, A. J., & Petty, H. R. (2016) · Nanotechnology · doi:10.1088/0957-4484/27/7/075103 · Cited by 11

Riccardin D-N induces lysosomal membrane permeabilization by inhibiting acid sphingomyelinase and interfering with sphingomyelin metabolism in vivo

Li, L., Niu, H., Sun, B., Xiao, Y., Li, W., Yuan, H., & Lou, H. (2016) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2016.09.014 · Cited by 11

Synergy of 2-deoxy-d-glucose combined with berberine in inducing the lysosome/autophagy and transglutaminase activation-facilitated apoptosis

Halicka, H. D., Garcia, J., Li, J., Zhao, H., & Darżynkiewicz, Z. (2016) · APOPTOSIS · doi:10.1007/s10495-016-1315-5 · Cited by 11

Identification of RNA aptamer which specifically interacts with PtdIns(3)P

Donia, T., Bala, J., Suizu, F., Hirata, N., Tanaka, T., Ishigaki, S., Pranzatelli, T. J. F., Nio‐Kobayashi, J., Iwanaga, T., Chiorini, J. A., et al. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.07.034 · Cited by 11

Ligand-receptor interaction in the specific targeting of biomimetic peptide nanoparticles to lysophosphatidylcholine

Wang, A., Yue, K., Zhong, W., Zhang, G., Wang, L., Wang, H., Zhang, H., & Zhang, X. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.12.162 · Cited by 11

Molecular mechanism underlying desensitization of the proton-activated chloride channel PAC

Osei‐Owusu, J., Ruan, Z., Mihaljević, L., Matasic, D. S., Chen, K. H., Lü, W., & Qiu, Z. (2022) · eLife · doi:10.7554/elife.82955 · Cited by 11

Review of Retinal Imaging Modalities for Hydroxychloroquine Retinopathy

Cheong, K. X., Ong, C., Chandrasekaran, P. R., Zhao, J., Teo, K. Y. C., & Mathur, R. (2023) · Diagnostics · doi:10.3390/diagnostics13101752 · Cited by 11

Oculocutaneous albinism: Developing novel antibodies targeting the proteins associated with OCA2 and OCA4

Kondo, T., Namiki, T., Coelho, S. G., Valencia, J. C., & Hearing, V. J. (2014) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2014.11.006 · Cited by 11

The vacuolar-type ATPase inhibitor archazolid increases tumor cell adhesion to endothelial cells by accumulating extracellular collagen

Luong, B., Schwenk, R., Bräutigam, J., Müller, R., Menche, D., Bischoff, I., & Fürst, R. (2018) · PLoS ONE · doi:10.1371/journal.pone.0203053 · Cited by 11

Photostable lysosomal imaging of living cell with hyperspectral stimulated Raman scattering microscopy using a probe based on bisarylbutadiyne

Ding, C., Chen, Y., Li, H., Wang, B., Wei, Q., Tang, H., Jia, S., He, Z., Wang, P., & Zhou, X. (2019) · Chinese Chemical Letters · doi:10.1016/j.cclet.2019.03.046 · Cited by 11

Dopamine D2 receptor activator quinpirole protects against trypsinogen activation during acute pancreatitis via upregulating HSP70

Ye, X., Han, X., Li, B., Dai, J., Wu, Z., He, Y., Wen, L., & Hu, G. (2020) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00354.2019 · Cited by 11

Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma

Wang, S., Xu, X., Che, D., Fan, R., Gao, M., Cao, Y., Ge, C., Feng, Y., Li, J., Xie, S., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222010987 · Cited by 11

Modulation of CD36 ‐mediated lipid accumulation and senescence by vitamin E analogs in monocytes and macrophages

Zingg, J.-M. A., Stamatiou, C., Montalto, G., & Daunert, S. (2022) · BioFactors · doi:10.1002/biof.1821 · Cited by 11

Local detection of pH-induced disaggregation of biocompatible micelles by fluorescence switch ON

Battistelli, G., Proetto, M. T., Mavridi‐Printezi, A., Calvaresi, M., Danielli, A., Costantini, P. E., Battistella, C., Gianneschi, N. C., & Montalti, M. (2022) · Chemical Science · doi:10.1039/d2sc00304j · Cited by 11

ICAM-1 Binding Rhinoviruses A89 and B14 Uncoat in Different Endosomal Compartments

Conzemius, R., Ganjian, H., Blaas, D., & Fuchs, R. (2016) · Journal of Virology · doi:10.1128/jvi.00712-16 · Cited by 11

TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvation

Ren, W., Jiang, H., Song, Q., Chen, Y., Tang, C., Wang, F., Zhu, J., Ren, J., Zhao, Y., He, Y., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116186 · Cited by 10

Organelle dysfunction and its contribution to metabolic impairments in aging and age-related diseases

Heiby, J. C., & Ori‬‬, A. (2022) · Current Opinion in Systems Biology · doi:10.1016/j.coisb.2022.100416 · Cited by 11

Pathological Functions of Lysosomal Ion Channels in the Central Nervous System

Cen, J.-K., Hu, N., Shen, J., Gao, Y., & Lu, H.-J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126565 · Cited by 10

Microenvironmental alkalization promotes the therapeutic effects of MSLN-CAR-T cells

Wu, M., Mao, L., Zhai, X., Liu, J., Wang, J., Li, L., Duan, J., Wang, J., Lin, S. J., Li, J., et al. (2024) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2024-009510 · Cited by 11

A gain-of-function mutation in ATP6V0A4 drives primary distal renal tubular alkalosis with enhanced V-ATPase activity

Peng, S.-Q., Wu, Q., Wang, W., Zhang, Y., Zhou, R.-N., Liao, J., Wei, J.-X., Yang, Y., Shi, W., Yang, J., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci188807 · Cited by 10

Inhibition of virally induced TFEB proteasomal degradation as a host-centric therapeutic approach for coronaviral infection

Lear, T., Larsen, M. B., Lin, B., Treat, B. R., Cao, Q. N., Boudreau, Á. N., Lockwood, K. C., Alfaras, I., Kennerdell, J. R., Salminen, L., et al. (2025) · Science Advances · doi:10.1126/sciadv.adv4033 · Cited by 11

Numb positively regulates autophagic flux via regulating lysosomal function

Sun, H., Liu, Y., Zhang, L., Shao, X., Liu, K., Ding, Z., Liu, X., Jiang, C., Li, H., & Li, H. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.07.084 · Cited by 10

Bifunctional reactive pentamethine cyanine dyes for biomedical applications

Rozovsky, A., Patsenker, L. D., & Gellerman, G. (2018) · Dyes and Pigments · doi:10.1016/j.dyepig.2018.09.064 · Cited by 10

The potential effectiveness of acetazolamide in the prevention of acute kidney injury in COVID-19: A hypothesis

Habibzadeh, P., Mofatteh, M., Ghavami, S., & Roozbeh, J. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173487 · Cited by 10

Optimal Use of 2′,7′-Dichlorofluorescein Diacetate in Cultured Hepatocytes

Reiniers, M. J., de Haan, L. R., Reeskamp, L. F., Broekgaarden, M., Hoekstra, R., van Golen, R. F., & Heger, M. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2099-1_39 · Cited by 10

Cerebrospinal fluid pH regulation

Damkier, H. H., & Prætorius, J. (2024) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-024-02917-0 · Cited by 11

Modulation of V-ATPase by βA3/A1-Crystallin in Retinal Pigment Epithelial Cells

Valapala, M., Sergeev, Y. V., Wawrousek, E. F., Hose, S., Zigler, J. S., & Sinha, D. (2015) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-17121-0_104 · Cited by 10

Disruption of artificial lipid bilayers in the presence of transition metal oxide and rare earth metal oxide nanoparticles

Acharya, S. J., Lu, B., Edwards, S., Toh, C., Petersen, A., Yong, C., Lyu, P., Huang, A., & Schmidt, J. J. (2018) · Journal of Physics D Applied Physics · doi:10.1088/1361-6463/aaeb6e · Cited by 10

Effect of increasing liver blood flow on nanodrug clearance by the liver for enhanced antitumor therapy

Li, Y., Wan, J., Wang, F., Guo, J., & Wang, C. (2019) · Biomaterials Science · doi:10.1039/c8bm01371c · Cited by 10

Autophagy: ‘Self-Eating’ Your Way to Longevity

Pattison, C. J., & Korolchuk, V. I. (2018) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-981-13-2835-0_2 · Cited by 10

Defective Cystinosin, Aberrant Autophagy−Endolysosome Pathways, and Storage Disease: Towards Assembling the Puzzle

Rega, L. R., Leo, E. D., Nieri, D., & Luciani, A. (2022) · Cells · doi:10.3390/cells11030326 · Cited by 10

Sulfatide with ceramide composed of phytosphingosine (t18:0) and 2-hydroxy FAs in renal intercalated cells

Nakashima, K., Hirahara, Y., Koike, T., Tanaka, S., Gamo, K., Oe, S., Hayashi, S., Seki, R., Nakano, Y., Ohe, C., et al. (2022) · Journal of Lipid Research · doi:10.1016/j.jlr.2022.100210 · Cited by 10

Recent advances in the intracellular delivery of macromolecule therapeutics

Chen, S., Xu, X., Li, X., Yi, N.-B., Li, S., Xiang, X.-C., Cheng, D., & Sun, T. (2022) · Biomaterials Science · doi:10.1039/d2bm01348g · Cited by 10

Genetic Diseases Associated with Protein Glycosylation Disorders in Mammals

Nakayama, Y., Nakamura, N., Tsuji, D., Ito, K., & Kurosak, A. (2013) · InTech eBooks · doi:10.5772/54097 · Cited by 10

The relationship between Cd‐induced autophagy and lysosomal activation in WRL‐68 cells

Meng, S., Mao, W., Wang, F., Liu, X., & Shao, L. (2015) · Journal of Applied Toxicology · doi:10.1002/jat.3114 · Cited by 10

Kinetic and spectroscopic responses of pH-sensitive nanoparticles: influence of the silica matrix

Clasen, A., Wenderoth, S., Tavernaro, I., Fleddermann, J., Kraegeloh, A., & Jung, G. (2019) · RSC Advances · doi:10.1039/c9ra06047b · Cited by 10

Caveolin‐3 loss linked with the P104L LGMD‐1C mutation modulates skeletal muscle mTORC1 signalling and cholesterol homeostasis

Shah, D. S., Nisr, R. B., Krasteva‐Christ, G., & Hundal, H. S. (2023) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13317 · Cited by 8

Weak base drug-induced endolysosome iron dyshomeostasis controls the generation of reactive oxygen species, mitochondrial depolarization, and cytotoxicity

Halcrow, P. W., Quansah, D. N. K., Kumar, N., Solloway, R. L., Teigen, K. M., Lee, K. A., Liang, B., & Geiger, J. D. (2024) · NeuroImmune Pharmacology and Therapeutics · doi:10.1515/nipt-2023-0021 · Cited by 8

Two-Step Enrichment Facilitates Background Reduction for Proteomic Analysis of Lysosomes

Bonini, S., & Winter, D. (2024) · Journal of Proteome Research · doi:10.1021/acs.jproteome.4c00053 · Cited by 10

Therapeutic effects of exendin‐4 on spinal cord injury via restoring autophagy function and decreasing necroptosis in neuron

Gao, X., Li, Q., Hao, J., Sun, K., Hu, F., Guo, K., & Gao, C. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14835 · Cited by 9

Organelle Communication with the Nucleus

Sengupta, S., & Levy, D. L. (2024) · Results and problems in cell differentiation · doi:10.1007/978-3-031-62036-2_1 · Cited by 10

Potential application of natural compounds in ischaemic stroke: Focusing on the mechanisms underlying “lysosomocentric” dysfunction of the autophagy-lysosomal pathway

Liu, Y., Liu, Q., Shang, H., Li, J., Chai, H., Wang, K., Guo, Z., Luo, T., Liu, S., Liu, Y., et al. (2024) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2024.108721 · Cited by 9

Lysosome-localization and tumor-targeting of novel photosensitizers enhance the ablation of cancer

Li, J., Wang, G., Mai, Y., Zhang, W., Zhao, H., Zhou, Y., Chen, L., Lin, Y., Jiang, L., Xu, P., et al. (2024) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2024.113045 · Cited by 9

Inhibition of the HV1 voltage-gated proton channel compromises the viability of human polarized macrophages in a polarization- and ceramide-dependent manner

Kovács, T., Szabo, B. C., Chandrakanthi, K. R., Szekelyhidi, V., Nagy, P., Varga, Z., Panyi, G., & Zákány, F. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1487578 · Cited by 9

Monitoring Autophagy in Human Aging: Key Cell Models and Insights

Moreno, T. M., Nieto-Torres, J. L., & Kumsta, C. (2025) · Frontiers in Bioscience-Landmark · doi:10.31083/fbl27091 · Cited by 8

The Rab3 family proteins in age-related neurodegeneration: unraveling molecular pathways and potential therapeutic targets

He, H., Ai, R., Fang, E. F., & Palikaras, K. (2025) · npj Aging · doi:10.1038/s41514-025-00257-6 · Cited by 10

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

Jiang, S., Fu, J., Li, S., Li, Z., Zhao, Q., Yin, Y., Yang, M., & Wang, Y. (2025) · Traffic · doi:10.1111/tra.70026 · Cited by 10

Lysosome pH Dynamics in Physiology and Disease: Molecular Mechanisms and Therapeutic Insights

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