The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
(T RANS)G ENE S ILENCING IN P LANTS: How Many Mechanisms?
Abstract
▪ Abstract Epigenetic silencing of transgenes and endogenous genes can occur at the transcriptional level (TGS) or at the posttranscriptional level (PTGS). Because they can be induced by transgenes and viruses, TGS and PTGS probably reflect alternative (although not exclusive) responses to two important stress factors that the plant's genome has to face: the stable integration of additional DNA into chromosomes and the extrachromosomal replication of a viral genome. TGS, which results from the impairment of transcription initiation through methylation and/or chromatin condensation, could derive from the mechanisms by which transposed copies of mobile elements and T-DNA insertions are tamed. PTGS, which results from the degradation of mRNA when aberrant sense, antisense, or double-stranded forms of RNA are produced, could derive from the process of recovery by which cells eliminate pathogens (RNA viruses) or their undesirable products (RNA encoded by DNA viruses). Mechanisms involving DNA-DNA, DNA-RNA, or RNA-RNA interactions are discussed to explain the various pathways for triggering (trans)gene silencing in plants.
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Citations
Cites
1 retracted
Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana
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RetractedA Species of Small Antisense RNA in Posttranscriptional Gene Silencing in Plants
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Cited by
RNA Interference: Biology, Mechanism, and Applications
Agrawal, N., Dasaradhi, P. V. N., Mohmmed, A., Malhotra, P., Bhatnagar, R. K., & Mukherjee, S. K. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.4.657-685.2003 · Cited by 1,305
A Systemic Small RNA Signaling System in Plants
Yoo, B.-C., Kragler, F., Varkonyi-Gasic, E., Haywood, V., Archer-Evans, S., Lee, Y. M., Lough, T. J., & Lucas, W. J. (2004) · The Plant Cell · doi:10.1105/tpc.104.023614 · Cited by 528
Erdmann, R. M., & Picard, C. L. (2020) · PLOS Genetics · doi:10.1371/journal.pgen.1009034 · Cited by 389
Expression of the Nicotiana protein kinase (NPK1) enhanced drought tolerance in transgenic maize.
Shou, H. (2004) · Journal of Experimental Botany · doi:10.1093/jxb/erh129 · Cited by 250
Insights into the conservation and diversification of the molecular functions of YTHDF proteins
(2023) · doi:10.1371/journal.pgen.1010980 · Cited by 29
Metadata
- Authors
- Fagard, M., & Vaucheret, H.
- Venue
- Annual Review of Plant Physiology and Plant Molecular Biology
- Publisher
- Annual Reviews
- Published
- 2000-06
- Volume
- 51
- Issue
- 1
- Pages
- 167-194
- ISSN
- 1040-2519 (ISSN-L)
- OpenAlex
- W1925002711
- Cited by
- 297
- References
- 82
- FWCI
- 45.76
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: (T RANS)G ENE S ILENCING IN P LANTS: How Many Mechanisms? https://app.cochat.ai/papers/10.1146/annurev.arplant.51.1.167
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- Fagard, M., & Vaucheret, H. (2000). (T RANS)G ENE S ILENCING IN P LANTS: How Many Mechanisms? Annual Review of Plant Physiology and Plant Molecular Biology. https://doi.org/10.1146/annurev.arplant.51.1.167
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
