The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
TRANSCRIPTIONAL REGULATION BY CYCLIC AMP
Abstract
A number of hormones and growth factors have been shown to stimulate target cells via second messenger pathways that in turn regulate the phosphorylation of specific nuclear factors. The second messenger cyclic AMP, for example, regulates a striking number of physiologic processes, including intermediary metabolism, cellular proliferation, and neuronal signaling, by altering basic patterns of gene expression. Our understanding of cyclic AMP signaling in the nucleus has expanded considerably over the past decade, owing in large part to the characterization of cyclic AMP–responsive promoter elements, transcription factors that bind them, and signal-dependent coactivators that mediate target gene induction. More importantly, these studies have revealed new insights into biological problems as diverse as biological clocks and long-term memory. The purpose of this review is to describe the components of the cyclic AMP response unit and to analyze how these components cooperate to induce target gene expression in response to hormonal stimulation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins
Landschulz, W. H., Johnson, P. F., & McKnight, S. L. (1988) · Science · doi:10.1126/science.3289117 · Cited by 3,443
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
Gonzalez, G. A., & Montminy, M. R. (1989) · Cell · doi:10.1016/0092-8674(89)90013-5 · Cited by 2,464
Self-citationPhosphorylated CREB binds specifically to the nuclear protein CBP
Chrivia, J. C., Kwok, R. P. S., Lamb, N., Hagiwara, M., Montminy, M. R., & Goodman, R. H. (1993) · Nature · doi:10.1038/365855a0 · Cited by 2,052
Self-citationCREB: a Ca 2+ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases
Sheng, M., Thompson, M. A., & Greenberg, M. E. (1991) · Science · doi:10.1126/science.1646483 · Cited by 1,488
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
Yang, X.-J., Ogryzko, V. V., Nishikawa, J.-I., Howard, B. H., & Nakatani, Y. (1996) · Nature · doi:10.1038/382319a0 · Cited by 1,479
Nuclear protein CBP is a coactivator for the transcription factor CREB
Kwok, R. P. S., Lundblad, J. R., Chrivia, J. C., Richards, J. P., Bächinger, H. P., Brennan, R. G., Roberts, S. G. E., Green, M. R., & Goodman, R. H. (1994) · Nature · doi:10.1038/370223a0 · Cited by 1,443
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.
Montminy, M. R., Sevarino, K. A., Wagner, J. A., Mandel, G., & Goodman, R. H. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.18.6682 · Cited by 1,385
Self-citationBinding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene
Montminy, M. R., & Bilezikjian, L. M. (1987) · Nature · doi:10.1038/328175a0 · Cited by 1,357
Self-citationPhosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB
Yamamoto, K. K., Gonzalez, G. A., Biggs, W. H., & Montminy, M. R. (1988) · Nature · doi:10.1038/334494a0 · Cited by 1,283
Self-citationThe regulation of transcription by phosphorylation
Hunter, T., & Karin, M. (1992) · Cell · doi:10.1016/0092-8674(92)90162-6 · Cited by 1,281
Cited by
Transcription Factors in Long-Term Memory and Synaptic Plasticity
Alberini, C. M. (2009) · Physiological Reviews · doi:10.1152/physrev.00017.2008 · Cited by 991
Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome
Guo, C., Xie, S., Chi, Z., Zhang, J., Liu, Y., Zhang, L., Zheng, M., Zhang, X., Xia, D., Ke, Y., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.09.008 · Cited by 838
Synnestvedt, K., Furuta, G. T., Comerford, K. M., Louis, N., Karhausen, J., Eltzschig, H. K., Hansen, K. R., Thompson, L. F., & Colgan, S. P. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215337 · Cited by 660
Activation of ATF6 and an ATF6 DNA Binding Site by the Endoplasmic Reticulum Stress Response
Wang, Y., Shen, J., Arenzana, N., Tirasophon, W., Kaufman, R. J., & Prywes, R. (2000) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)61473-0 · Cited by 616
The enhanceosome and transcriptional synergy.
Carey, M. (1998) · Cell · doi:10.1016/s0092-8674(00)80893-4 · Cited by 553
Metadata
- Authors
- Montminy, M.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 1997-06
- Volume
- 66
- Issue
- 1
- Pages
- 807-822
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2022713347
- Cited by
- 962
- References
- 74
- FWCI
- 3.85
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: TRANSCRIPTIONAL REGULATION BY CYCLIC AMP. https://app.cochat.ai/papers/10.1146/annurev.biochem.66.1.807
- The paper
- Montminy, M. (1997). TRANSCRIPTIONAL REGULATION BY CYCLIC AMP. Annual Review of Biochemistry. https://doi.org/10.1146/annurev.biochem.66.1.807
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
