The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
CELLULAR DNA REPLICASES: Components and Dynamics at the Replication Fork
Abstract
▪ Abstract Chromosomal DNA replicases are multicomponent machines that have evolved clever strategies to perform their function. Although the structure of DNA is elegant in its simplicity, the job of duplicating it is far from simple. At the heart of the replicase machinery is a heteropentameric AAA+ clamp-loading machine that couples ATP hydrolysis to load circular clamp proteins onto DNA. The clamps encircle DNA and hold polymerases to the template for processive action. Clamp-loader and sliding clamp structures have been solved in both prokaryotic and eukaryotic systems. The heteropentameric clamp loaders are circular oligomers, reflecting the circular shape of their respective clamp substrates. Clamps and clamp loaders also function in other DNA metabolic processes, including repair, checkpoint mechanisms, and cell cycle progression. Twin polymerases and clamps coordinate their actions with a clamp loader and yet other proteins to form a replisome machine that advances the replication fork.
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Cites
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
Sancar, A., Lindsey-Boltz, L. A., Ünsal-Kaçmaz, K., & Linn, S. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073723 · Cited by 3,317
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DNA Polymerase γ, The Mitochondrial Replicase
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Cited by
PCNA, the Maestro of the Replication Fork
Moldovan, G.-L., Pfander, B., & Jentsch, S. (2007) · Cell · doi:10.1016/j.cell.2007.05.003 · Cited by 1,796
Oxidative Stress Resistance in Deinococcus radiodurans
Slade, D., & Radman, M. (2011) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00015-10 · Cited by 761
Ogi, T., Limsirichaikul, S., Overmeer, R. M., Volker, M., Takenaka, K., Cloney, R., Nakazawa, Y., Niimi, A., Miki, Y., Jaspers, N. G., et al. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.02.009 · Cited by 392
Metabolism, cell growth and the bacterial cell cycle
Wang, J. D., & Levin, P. A. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2202 · Cited by 351
Goodman, M. F., & Woodgate, R. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a010363 · Cited by 317
“Whereas a Pol III replisome performs rapid and processive “error-free” genome replication on undamaged DNA (Johnson and O’Donnell 2005; McHenry 2011), a mutasome would perform slow, poorly processive, “error-prone” TLS. Biochemical Characterization of the E. coli Umu Proteins and Evolution of TLS…”
BackgroundInfluential
Metadata
- Authors
- Johnson, A., & O'Donnell, M.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 2005-06-01
- Volume
- 74
- Issue
- 1
- Pages
- 283-315
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2119344497
- Cited by
- 562
- References
- 7
- FWCI
- 2.66
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
