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Cited by 1,909

The DOI matches its Crossref record; 230 of the 230 references it cites were found in a registry or an index.

TRP Channels

Open access
Venkatachalam, Kartik, Montell, Craig·2007·Annual Review of Biochemistry

Abstract

The TRP (Transient Receptor Potential) superfamily of cation channels is remarkable in that it displays greater diversity in activation mechanisms and selectivities than any other group of ion channels. The domain organizations of some TRP proteins are also unusual, as they consist of linked channel and enzyme domains. A unifying theme in this group is that TRP proteins play critical roles in sensory physiology, which include contributions to vision, taste, olfaction, hearing, touch, and thermo- and osmosensation. In addition, TRP channels enable individual cells to sense changes in their local environment. Many TRP channels are activated by a variety of different stimuli and function as signal integrators. The TRP superfamily is divided into seven subfamilies: the five group 1 TRPs (TRPC, TRPV, TRPM, TRPN, and TRPA) and two group 2 subfamilies (TRPP and TRPML). TRP channels are important for human health as mutations in at least four TRP channels underlie disease.

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Crossref · 10.1146/annurev.biochem.75.103004.142819

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Metadata

Authors
Venkatachalam, K., & Montell, C.
Venue
Annual Review of Biochemistry
Published
2007-06-07
Volume
76
Issue
1
Pages
387-417
ISSN
  • 0066-4154 (ISSN-L)
  • 1545-4509
OpenAlex
W4233595534
Cited by
1,909
References
230
FWCI
4.20
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: TRP Channels. https://app.cochat.ai/papers/10.1146/annurev.biochem.75.103004.142819
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Venkatachalam, K., & Montell, C. (2007). TRP Channels. Annual Review of Biochemistry. https://doi.org/10.1146/annurev.biochem.75.103004.142819

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.