The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Structure and Mechanism of Helicases and Nucleic Acid Translocases
Abstract
Helicases and translocases are a ubiquitous, highly diverse group of proteins that perform an extraordinary variety of functions in cells. Consequently, this review sets out to define a nomenclature for these enzymes based on current knowledge of sequence, structure, and mechanism. Using previous definitions of helicase families as a basis, we delineate six superfamilies of enzymes, with examples of crystal structures where available, and discuss these structures in the context of biochemical data to outline our present understanding of helicase and translocase activity. As a result, each superfamily is subdivided, where appropriate, on the basis of mechanistic understanding, which we hope will provide a framework for classification of new superfamily members as they are discovered and characterized.
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Cites
The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants
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Crystal structure of a DExx box DNA helicase
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The cerebellum ages slowly according to the epigenetic clock
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Short-range translocation by a restriction enzyme motor triggers diffusion along DNA
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The SSU Processome Component Utp25p is a Pseudohelicase
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Metadata
- Authors
- Singleton, M. R., Dillingham, M. S., & Wigley, D. B.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 2007-06-07
- Volume
- 76
- Issue
- 1
- Pages
- 23-50
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2105439835
- Cited by
- 1,274
- References
- 3
- FWCI
- 3.26
- Type
- journal article
- Language
- en
- Open access
- closed
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