The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
The State of Lipid Rafts: From Model Membranes to Cells
Abstract
▪ Abstract Lipid raft microdomains were conceived as part of a mechanism for the intracellular trafficking of lipids and lipid-anchored proteins. The raft hypothesis is based on the behavior of defined lipid mixtures in liposomes and other model membranes. Experiments in these well-characterized systems led to operational definitions for lipid rafts in cell membranes. These definitions, detergent solubility to define components of rafts, and sensitivity to cholesterol deprivation to define raft functions implicated sphingolipid- and cholesterol-rich lipid rafts in many cell functions. Despite extensive work, the basis for raft formation in cell membranes and the size of rafts and their stability are all uncertain. Recent work converges on very small rafts <10 nm in diameter that may enlarge and stabilize when their constituents are cross-linked.
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Cites
Functional rafts in cell membranes
Simons, K., & Ikonen, E. (1997) · Nature · doi:10.1038/42408 · Cited by 9,757
PIP2and Proteins: Interactions, Organization, and Information Flow
McLaughlin, S., Wang, J., Gambhir, A., & Murray, D. (2002) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.31.082901.134259 · Cited by 837
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Localized Biphasic Changes in Phosphatidylinositol-4,5-Bisphosphate at Sites of Phagocytosis
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Molecular organization of cholesterol in polyunsaturated membranes: microdomain formation
Brzustowicz, M. R., Cherezov, V., Caffrey, M., Stillwell, W., & Wassall, S. R. (2002) · Biophysical Journal · doi:10.1016/s0006-3495(02)75394-0 · Cited by 161
Cited by
Pathways of clathrin-independent endocytosis
Mayor, S., & Pagano, R. E. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2216 · Cited by 1,556
Exosomes: endosomal-derived vesicles shipping extracellular messages
Février, B., & Raposo, G. (2004) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2004.06.003 · Cited by 881
Lipid rafts: contentious only from simplistic standpoints
Hancock, J. F. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1925 · Cited by 788
Lipid rafts and membrane dynamics
Rajendran, L., & Simons, K. (2005) · Journal of Cell Science · doi:10.1242/jcs.01681 · Cited by 593
Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane
Booth, A. M., Fang, Y., Fallon, J. K., Yang, J.-M., Hildreth, J. E. K., & Gould, S. J. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200508014 · Cited by 561
Metadata
- Authors
- Edidin, M.
- Venue
- Annual Review of Biophysics and Biomolecular Structure
- Publisher
- Annual Reviews
- Published
- 2003-06
- Volume
- 32
- Issue
- 1
- Pages
- 257-283
- ISSN
- 1056-8700 (ISSN-L)
- 1545-4266
- OpenAlex
- W2122882997
- Cited by
- 1,341
- References
- 6
- FWCI
- 40.75
- Type
- journal article
- Language
- en
- Open access
- closed
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